GRAIL
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured.
Menlo Park, CA
Hybrid

Process Engineer 2 - NGS

Sorry, this job was removed at 3:06 a.m. (PST) on Friday, December 4, 2020
Find out who's hiring in Peninsula.
See all Developer + Engineer jobs in Peninsula
Apply
By clicking Apply Now you agree to share your profile information with the hiring company.

GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is headquartered in Menlo Park, CA with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies. For more information, please visit www.grail.com.

As a Process Engineer 2 at GRAIL, you will support development projects by contributing to a dynamic Product Development team. The ideal candidate will possess experience developing manufacturing processes applicable to a high-throughput production or molecular testing environment, including evaluating and characterizing equipment and reagents, designing and testing manufacturing processes, and drafting documentation including protocols, reports and operating instructions. Candidates should possess strong troubleshooting skills and be a team player.

You Will:

  • Develop and validate test methods for new reagents and instruments, including NGS oligos and molecular diagnostics equipment. 
  • Design, characterize, and execute new laboratory equipment qualification processes within an NGS setting. 
  • Participate in the development of product plans, evaluation of processes and process risk, and development of project timelines.
  • Manage projects and relationships with critical material suppliers.
  • Contribute to the planning, preparation, and execution of experiments to support development of the next generation of GRAIL technology.
  • Develop strategies for characterization of automated processes, including determination of critical process parameters, control limits, and SPC rulesets.
  • Sustain existing platforms through continuous improvement efforts, failure analysis, and maintenance of supporting documentation.
  • Support the transfer and execution of equipment qualification protocols at CMOs.
  • Troubleshoot procedures and recommend improvements or alternative procedures if needed.
  • Responsible for accurately recording work performed per GLP, including results and methodology.
  • Calculate, compile and analyze experimental data.
  • Ensure laboratory activities are performed in compliance with procedures and safety guidelines when handling, storing, and disposing of hazardous or biohazardous materials.
  • Write reports, work instructions, and SOPs for development and transfer activities.
  • Present data at technical meetings.

Your Background Will Include:

  • B.S. in biochemistry, molecular biology, bioengineering, or related fields preferred. M.S. is a plus.
  •  4+ years of experience in the medical device or pharmaceutical industry working in process engineering, R&D, or systems engineering. 
  • Experience with product development including process validation, equipment qualification (IQ/OQ/PQ), tech transfer, and process characterization required.
  • Demonstrated success in technical proficiency, creativity and collaboration with others. Experience in design of studies for the evaluation and qualification of NGS-related equipment in a regulated environment is desired.
  • Must have excellent personal task management skills and a high level of self-motivation.
  • Expertise in molecular biology.
  • Experience with nucleic acid extraction technologies.
  • Experience with Design of Experiment methodology.
  • Experience with Six Sigma, CIP, Root Cause Analysis techniques.
  • Experience with medical device regulatory requirements and ISO quality standards.
  • Experience with automated laboratory equipment such as robotic liquid handlers and qPCR instruments.
  • Theoretical and practical knowledge of Next Generation Sequencing sample preparation workflows and applications preferred.
  • Excellent verbal and written communication skills and willingness to collaborate cross-functionally.

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

See More
Apply Now
By clicking Apply Now you agree to share your profile information with the hiring company.

What are GRAIL Perks + Benefits

GRAIL Benefits Overview

We’re committed to creating the best experience for everyone at GRAIL, ensuring that each member of our team has comprehensive benefits and resources to thrive at all stages of life, both at work and at home.

Culture
Volunteer in local community
We parter with Bay Area local partners such as Life Science Cares to help meet basic needs in the community.
Partners with nonprofits
GRAIL partners with The Honor Foundation to facilitate mock interviews to help military professionals transition to civilian life. Also oSTEM and The National Sales Network to identify diverse talent.
Open door policy
OKR operational model
Team based strategic planning
Open office floor plan
Employee resource groups
Employee-led culture committees
Hybrid work model
In-person all-hands meetings
Employee awards
Flexible work schedule
Remote work program
Diversity
Dedicated diversity and inclusion staff
Mandated unconscious bias training
Unconscious bias training is included as part of our standard interview training. We also have a formal training on the topic of unconscious bias that is facilitated by the People Team.
Diversity manifesto
Mean gender pay gap below 10%
Diversity employee resource groups
GRAIL proudly offers 4 employee resources groups led by team members in tandem with an executive sponsor. They include: ASERG, WERG, PRIDE, and BIPOCC.
Hiring practices that promote diversity
GRAIL's Talent team has partnered with a variety of non-profits, associations and job boards including WITI, oSTEM, THF, DiversityJobs and The National Sales Network to identify diverse talent.
Health Insurance & Wellness Benefits
Flexible Spending Account (FSA)
Disability insurance
Dental insurance
Vision insurance
Health insurance
Life insurance
Wellness programs
Team workouts
Mental health benefits
Abortion travel benefits
Financial & Retirement
401(K)
401(K) matching
Company equity
Performance bonus
Pay transparency
Child Care & Parental Leave Benefits
Childcare benefits
Generous parental leave
Family medical leave
Company sponsored family events
Fertility benefits
Vacation & Time Off Benefits
Unlimited vacation policy
Paid holidays
Paid sick days
Flexible time off
Bereavement leave benefits
Company-wide vacation
Office Perks
Commuter benefits
Company-sponsored outings
Free daily meals
Free snacks and drinks
Some meals provided
Company-sponsored happy hours
Onsite office parking
Recreational clubs
Relocation assistance
Onsite gym
Professional Development Benefits
Job training & conferences
Promote from within
Mentorship program
Online course subscriptions available
Paid industry certifications

More Jobs at GRAIL

Apply Now
By clicking Apply Now you agree to share your profile information with the hiring company.
Learn more about GRAILFind similar jobs like this