GRAIL
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured.
Menlo Park, CA
Hybrid

Manager, Technical Operations - Menlo Park, CA

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GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is headquartered in Menlo Park, CA with locations in Washington, D.C., North Carolina, and the United Kingdom. GRAIL, LLC is a wholly-owned subsidiary of Illumina, Inc. (NASDAQ:ILMN). For more information, please visit www.grail.com.


GRAIL is seeking a Manager to lead Technical Operations in Menlo Park, CA, who will be primarily responsible for supporting troubleshooting of Lab Operations activities and ensuring the efficient execution of GRAIL assays, and supporting Pharma partnerships. The candidate will be leading the development and growth of the Technical Operations team in Menlo Park, including staffing and training on various evolving GRAIL assays and workflows. The ideal candidate is a detail-oriented, dynamic team player with deep experience in executing and troubleshooting automated and manual NGS assay execution. The candidate is expected to partner with many functions of our organization, including Automation, Product Management, Product Development, LIMS, Quality, Supply Chain, Biosample Operations, and the Clinical Lab, to track tasks and investigations, delegate work to direct reports. This candidate will play an instrumental role in the implementation of the Technical Operations team. 

Duties & Responsibilities:

  • Develop and Manage day-to-day Technical Operations team in Menlo ParkAccountable for triage, investigation, management, and resolution of issues arising in MPK operations
  • Coordinate development of new workflows, incorporating input from various stakeholders including R&D, Biosample Operations, and Supply Chain
  • Become an expert on current production assays, late-stage development projectsContribute to and troubleshoot and optimization of manufacturing processes, automated assays, and test methodsLed cross-functional teams in planning, execution, and documentation of experiments for troubleshooting commercial NGS workflows
  • Identify opportunities for operational improvements, optimization, and cost reductionLead implementation of changes in material, process, or specifications in coordination with Quality and departmental owners
  • Provide technical leadership to project teams and ensure proper record keeping 
  • Actively participate and engage in the development, transfer, and implementation of new assays and technologies in collaboration with R&D
  • Coordinate cross-site functional reviews

Minimum Qualifications:

  • Demonstrated success in technical leadership, problem-solving, and collaboration with others. Experience in IVD or assay development in a regulated environment is preferred.
  • B.Sc in Biology, Chemistry, Molecular Biology or related field, an advanced degree strongly preferred with 6 years of relevant experience
  • 4+ years of experience in Next Generation Sequencing assays and workflows
  • 2+ years of direct management experience having hired, trained, and led high performing teams in a fast-paced production-like environment
  • Experience with automated and manual sample preparation workflowsFamiliarity with nucleic acids extraction techniques and quantification devices (e.g., Nanodrop, Bioanalyzer, Fragment Analyzer, ddPCR)
  • Experience product transfer and verification in an ISO or FDA-regulated environment desired.
  • Practical knowledge of Next Generation Sequencing sample preparation workflows and applications preferred.
  • Excellent verbal and written communication skills and willingness to collaborate cross-functionally across Quality, Regulatory, Operations, and Development teams
  • Strong interpersonal, negotiation, and influencing skills
  • Supervisory/mentoring experience and working in project teams
  • Technical leadership, self-direction, and willingness to both teach others and learn new techniques is highly desirable
  • General computer skills and proficiency in GSuite

GRAIL is an Equal Employment Office and Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status. We will reasonably accommodate all individuals with disabilities so that they can participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.


Following extensive monitoring, research, consideration of business implications, and advice from internal and external experts, GRAIL has made the decision to require all U.S. employees receive the COVID-19 vaccines as a condition of employment. “Full vaccination” is defined as two weeks after both doses of a two-dose vaccine or two weeks since a single-dose vaccine has been administered. Anyone unable to be vaccinated, either because of a sincerely held religious belief or a medical condition or disability that prevents them from being vaccinated, can request a reasonable accommodation.

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What are GRAIL Perks + Benefits

GRAIL Benefits Overview

We’re committed to creating the best experience for everyone at GRAIL, ensuring that each member of our team has comprehensive benefits and resources to thrive at all stages of life, both at work and at home.

Culture
Volunteer in local community
We parter with Bay Area local partners such as Life Science Cares to help meet basic needs in the community.
Partners with nonprofits
GRAIL partners with The Honor Foundation to facilitate mock interviews to help military professionals transition to civilian life. Also oSTEM and The National Sales Network to identify diverse talent.
Open door policy
OKR operational model
Team based strategic planning
Open office floor plan
Employee resource groups
Employee-led culture committees
Hybrid work model
In-person all-hands meetings
Employee awards
Flexible work schedule
Remote work program
Diversity
Dedicated diversity and inclusion staff
Mandated unconscious bias training
Unconscious bias training is included as part of our standard interview training. We also have a formal training on the topic of unconscious bias that is facilitated by the People Team.
Diversity manifesto
Mean gender pay gap below 10%
Diversity employee resource groups
GRAIL proudly offers 4 employee resources groups led by team members in tandem with an executive sponsor. They include: ASERG, WERG, PRIDE, and BIPOCC.
Hiring practices that promote diversity
GRAIL's Talent team has partnered with a variety of non-profits, associations and job boards including WITI, oSTEM, THF, DiversityJobs and The National Sales Network to identify diverse talent.
Health Insurance & Wellness Benefits
Flexible Spending Account (FSA)
Disability insurance
Dental insurance
Vision insurance
Health insurance
Life insurance
Wellness programs
Team workouts
Mental health benefits
Abortion travel benefits
Financial & Retirement
401(K)
401(K) matching
Company equity
Performance bonus
Pay transparency
Child Care & Parental Leave Benefits
Childcare benefits
Generous parental leave
Family medical leave
Company sponsored family events
Fertility benefits
Vacation & Time Off Benefits
Unlimited vacation policy
Paid holidays
Paid sick days
Flexible time off
Bereavement leave benefits
Company-wide vacation
Office Perks
Commuter benefits
Company-sponsored outings
Free daily meals
Free snacks and drinks
Some meals provided
Company-sponsored happy hours
Onsite office parking
Recreational clubs
Relocation assistance
Onsite gym
Professional Development Benefits
Job training & conferences
Promote from within
Mentorship program
Online course subscriptions available
Paid industry certifications

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