Jobs at Summit Therapeutics, Inc.

Lead strategic and operational study start‑up activities for global Phase 3 oncology trials, driving site selection, regulatory/ethics submissions, contract and budget execution, vendor oversight, timelines/metrics, risk mitigation, inspection readiness, and team development to ensure timely site activation and compliance with GCP and internal SOPs.

Lead portfolio and new-indication strategy for oncology, delivering market and competitive intelligence, forecasting/NPV models, market research, TPP alignment, and cross-functional strategic recommendations to inform executive decisions and BD opportunities.

The Director of Biostatistics leads statistical strategy and analysis for clinical trials in oncology, collaborating with clinical teams and regulatory bodies.

The Associate Director of Biostatistics provides statistical support for clinical trials in oncology, overseeing study design, analysis, and regulatory submissions while collaborating with cross-functional teams.

The Accounting Manager oversees R&D accruals and expenses for non-clinical trial activities, ensuring accurate financial reporting and collaboration with internal teams and vendors.

The Senior Director of Technical QA is responsible for overseeing GMP quality across the CMC lifecycle, managing relationships with CMOs, and ensuring inspection readiness for clinical and commercial manufacturing operations.

Lead strategic and operational program and portfolio management for oncology drug development. Drive cross-functional alignment, governance, milestone planning, scenario and risk management, and executive reporting. Oversee program execution, integrated timelines, budgets, and vendor/partner relationships while mentoring program management leaders and improving processes and tools.

Lead global regulatory strategy for oncology programs from IND/CTA through BLA/MAA and post‑marketing. Provide cross‑functional regulatory leadership, lead due diligence for partnerships, mentor RA staff, drive labeling and risk‑mitigation strategy, liaise with global authorities, and support product launch activities with minimal oversight.

The Corporate Counsel, Clinical Contracts drafts and negotiates contracts for clinical trials and other legal agreements, ensuring compliance and reducing risk for the company.

The Safety Physician Director is responsible for pharmacovigilance activities, including medical review of safety reports, ensuring regulatory compliance, and mentoring junior staff.

The Sr. Commercial Attorney will support the launch of Ivonescimab by drafting and negotiating commercial agreements, ensuring compliance with regulations, and advising on market strategies.