GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured.

Medical Director, Clinical Development # 3729

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Employer Provided Salary: 245,000-327,000 Annually
Salary data is provided by the employer. Please note this is not a guarantee of compensation.

GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is headquartered in Menlo Park, CA with locations in Washington, D.C., North Carolina, and the United Kingdom. GRAIL, LLC is a wholly-owned subsidiary of Illumina, Inc. (NASDAQ:ILMN). For more information, please visit

The Medical Director in Clinical Development is responsible for providing clinical expertise to support the design, conduct, and analysis of clinical and real-world evidence studies in support of GRAIL’s product pipeline as well as commercial launch and post-marketing commitments. This role will interact with cross-functional teams, including colleagues from Clinical Operations, Biostatistics, Clinical Data Management, Medical Affairs, Regulatory Affairs, Research and others. This position is based in Menlo Park, CA. with requirement of being 2 days onsite every week.


  • Act as a medical monitor for designated clinical and/or real-world evidence studies, serving as a member of the cross-functional clinical study management team
  • Issue queries and communicate with clinical study site staff to ensure completeness and accuracy of clinical data
  • Prepare and review answers to safety queries from regulatory authorities and IRBs as needed
  • Collaborate with other medical directors, clinical scientists, clinical data managers, biostatisticians, data scientists, and other functional stakeholders on the design, conduct, and analysis of clinical studies
  • Collaborate with colleagues from biostatistics to develop statistical analysis plans and serve as a co-author on clinical study reports and other study deliverables
  • Contribute to the development and preparation of regulatory documents
  • Provide scientific and medical support for publications and presentations to ensure scientific and medical accuracy and cross-functional alignment
  • Support efforts to advance clinical development and scientific research plans (review and interpretation of study data; engagement of key opinion leaders; providing strategic and scientific input to study-level and program-level teams)
  • Develop formal networks with external investigators and thought leaders to support clinical study programs
  • Ensure compliance with industry regulations, policies, guidelines and standards

Preferred Qualifications:

  • MD required, board certified/board eligible in oncology strongly preferred
  • 2 + years of clinical practice experience
  • 3 + years of experience in a diagnostics or pharmaceutical Clinical Development setting
  • Prior experience in a medial monitoring role, including medical case review and assessment of adverse event reports to determine seriousness and report-ability
  • Experience in designing and conducting clinical studies, particularly registrational and/or clinical utility studies for reimbursement
  • Experience in oncology, genomics, diagnostics, cell-free DNA-based applications, or similar applied medical fields is strongly preferred
  • Familiarity with the development of real-world evidence from real-world data (e.g., healthcare claims or electronic health records)
  • Knowledge of regulatory requirements (e.g. ICH, GCP, HIPAA, ISO) and a commitment to compliance
  • Experience authoring Standard Operating Procedures (SOPs) and similar documents in support of the role and responsibilities of a Medical Director
  • Excellent verbal and written communication skills, including clear and confident presentation skills
  • Ability to network and partner within external investigator and national organizations
  • Results oriented and strong attention to detail
  • Strong leadership and collaboration skills

The expected, full-time, annual base pay scale for this position is $245,000.00 - 327,000.00.  Actual base pay will consider skills, experience, and location.

Based on the role, colleagues may be eligible to participate in an annual bonus plan tied to company and individual performance, or an incentive plan. We also offer a long-term incentive plan to align company and colleague success over time.

In addition, GRAIL offers a progressive benefit package, including flexible time-off, a 401k with a company match, and alongside our medical, dental, vision plans, carefully selected mindfulness offerings.

GRAIL is an Equal Employment Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status. We will reasonably accommodate all individuals with disabilities so that they can participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. GRAIL maintains a drug-free workplace.

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What are GRAIL Perks + Benefits

GRAIL Benefits Overview

We’re committed to creating the best experience for everyone at GRAIL, ensuring that each member of our team has comprehensive benefits and resources to thrive at all stages of life, both at work and at home.

Volunteer in local community
We parter with Bay Area local partners such as Life Science Cares to help meet basic needs in the community.
Partners with nonprofits
GRAIL partners with The Honor Foundation to facilitate mock interviews to help military professionals transition to civilian life. Also oSTEM and The National Sales Network to identify diverse talent.
Open door policy
OKR operational model
Team based strategic planning
Open office floor plan
Employee resource groups
Employee-led culture committees
Hybrid work model
In-person all-hands meetings
Employee awards
Flexible work schedule
Remote work program
Dedicated diversity and inclusion staff
Mandated unconscious bias training
Unconscious bias training is included as part of our standard interview training. We also have a formal training on the topic of unconscious bias that is facilitated by the People Team.
Diversity manifesto
Mean gender pay gap below 10%
Diversity employee resource groups
GRAIL proudly offers 4 employee resources groups led by team members in tandem with an executive sponsor. They include: ASERG, WERG, PRIDE, and BIPOCC.
Hiring practices that promote diversity
GRAIL's Talent team has partnered with a variety of non-profits, associations and job boards including WITI, oSTEM, THF, DiversityJobs and The National Sales Network to identify diverse talent.
Health Insurance + Wellness
Flexible Spending Account (FSA)
Disability insurance
Dental insurance
Vision insurance
Health insurance
Life insurance
Wellness programs
Team workouts
Mental health benefits
Abortion travel benefits
Financial & Retirement
401(K) matching
Company equity
Performance bonus
Pay transparency
Child Care & Parental Leave
Childcare benefits
Generous parental leave
Family medical leave
Company sponsored family events
Fertility benefits
Vacation + Time Off
Unlimited vacation policy
Paid holidays
Paid sick days
Flexible time off
Bereavement leave benefits
Company-wide vacation
Office Perks
Commuter benefits
Company-sponsored outings
Free daily meals
Free snacks and drinks
Some meals provided
Company-sponsored happy hours
Onsite office parking
Recreational clubs
Relocation assistance
Onsite gym
Professional Development
Job training & conferences
Promote from within
Mentorship program
Online course subscriptions available
Paid industry certifications

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