GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured.

Senior Security Incident Manager #3596

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Employer Provided Salary: 160,000-185,000 Annually
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GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is headquartered in Menlo Park, CA with locations in Washington, D.C., North Carolina, and the United Kingdom. GRAIL, LLC is a wholly-owned subsidiary of Illumina, Inc. (NASDAQ:ILMN). For more information, please visit

GRAIL is seeking an experienced and proactive Senior Security Incident Manager to spearhead the development and implementation of our global incident framework. In this critical role, you will be responsible for facilitating and managing security incidents, driving incident response and remediation efforts, and collaborating with cross-functional teams to elevate the overall security posture across the organization.

This is an exciting green field opportunity with high visibility to initiate and operationalize an incident response program, improve and track incident-related remediations and help left shift security into Grail’s software, systems, process and culture.. You will be in a position to help ensure GRAIL protects the information we receive as part of our mission to help detect cancer!

This is a hybrid role and requires you to be onsite 2 days a week in Menlo Park, CA


  • Augment Grail’s Threat Detection and Response function in managing the lifecycles of all security incidents globally.
  • Continuously drive workflow improvement of Incident Management Process via systems, procedures, documentations, trainings and culture influences.
  • Identify and coordinate with peer incident responders from other non-security domains worldwide on triaging and standardize incident practices.
  • Work with functional managers to align resources, issues and schedules as related to incident remediations and mitigations.
  • Assemble, work with, and manage cross-organizational teams
  • Support accurate and consistent maintenance of technical and management escalation processes.
  • Primary lead for Customer Support during customer-related security events, issues or incidents.
  • Ownership and execution of the active critical security incident management process (below)
  • Manage event communications (below)


  • Facilitate the resolution effort and determine when it is necessary to engage additional resources if the resolution effort is stalled during the call with stakeholders
  • Engagement of escalation management resources
  • Draft and manage customer and internal communications for CSO/Legal/PR review and release, assist with further customer inquiries as the internal liaison as required.
  • Incident timeline and impact documentations and review


  • Establish and manage bridge calls with engineers and customers on single customer outage
  • Attend and drive multi-customer outage bridges
  • Crafts business appropriate communications for the affected operating groups and manages communication on a critical incident conference call
  • Post event program management
  • Incident Resolution handoffs along with detailed notes and a summary of the business impact and duration to the Problem Management team
  • Perform other duties and projects as assigned


  • The ideal candidate will bring 5+ year’s experience in critical/crisis situation management for technical customer escalations
  • Bachelor’s degree in business, computer science, engineering or related field or equivalent experience
  • Excellent communication skills (both verbal and written)
  • Experience supporting and managing technical environments; demonstrated leadership skills under fast-paced, highly dynamic situations
  • Excellent written and verbal communication skills are required, including the ability to communicate technical concepts clearly and effectively.
  • The ability to communicate confidently and clearly on conference calls, in meetings and via email, at all levels of the organization is essential.
  • A team player who is influential and builds good working relationships across all functions.
  • Ability to facilitate conversations with large groups of remote people.
  • Ability to maintain calm during stressful situations.


  • Incident Commander certification, level 5.

The expected, full-time, annual base pay scale for this position is $160,000-$185,000. Actual base pay will consider skills, experience, and location.

Based on the role, colleagues may be eligible to participate in an annual bonus plan tied to company and individual performance, or an incentive plan. We also offer a long-term incentive plan to align company and colleague success over time.

In addition, GRAIL offers a progressive benefit package, including flexible time-off, a 401k with a company match, and alongside our medical, dental, vision plans, carefully selected mindfulness offerings.

GRAIL is an Equal Employment Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status. We will reasonably accommodate all individuals with disabilities so that they can participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. GRAIL maintains a drug-free workplace.

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What are GRAIL Perks + Benefits

GRAIL Benefits Overview

We’re committed to creating the best experience for everyone at GRAIL, ensuring that each member of our team has comprehensive benefits and resources to thrive at all stages of life, both at work and at home.

Volunteer in local community
We parter with Bay Area local partners such as Life Science Cares to help meet basic needs in the community.
Partners with nonprofits
GRAIL partners with The Honor Foundation to facilitate mock interviews to help military professionals transition to civilian life. Also oSTEM and The National Sales Network to identify diverse talent.
Open door policy
OKR operational model
Team based strategic planning
Open office floor plan
Employee resource groups
Employee-led culture committees
Hybrid work model
In-person all-hands meetings
Employee awards
Flexible work schedule
Remote work program
Dedicated diversity and inclusion staff
Mandated unconscious bias training
Unconscious bias training is included as part of our standard interview training. We also have a formal training on the topic of unconscious bias that is facilitated by the People Team.
Diversity manifesto
Mean gender pay gap below 10%
Diversity employee resource groups
GRAIL proudly offers 4 employee resources groups led by team members in tandem with an executive sponsor. They include: ASERG, WERG, PRIDE, and BIPOCC.
Hiring practices that promote diversity
GRAIL's Talent team has partnered with a variety of non-profits, associations and job boards including WITI, oSTEM, THF, DiversityJobs and The National Sales Network to identify diverse talent.
Health Insurance + Wellness
Flexible Spending Account (FSA)
Disability insurance
Dental insurance
Vision insurance
Health insurance
Life insurance
Wellness programs
Team workouts
Mental health benefits
Abortion travel benefits
Financial & Retirement
401(K) matching
Company equity
Performance bonus
Pay transparency
Child Care & Parental Leave
Childcare benefits
Generous parental leave
Family medical leave
Company sponsored family events
Fertility benefits
Vacation + Time Off
Unlimited vacation policy
Paid holidays
Paid sick days
Flexible time off
Bereavement leave benefits
Company-wide vacation
Office Perks
Commuter benefits
Company-sponsored outings
Free daily meals
Free snacks and drinks
Some meals provided
Company-sponsored happy hours
Onsite office parking
Recreational clubs
Relocation assistance
Onsite gym
Professional Development
Job training & conferences
Promote from within
Mentorship program
Online course subscriptions available
Paid industry certifications

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