GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured.

Staff Data Engineer (Menlo Park, CA) #3378

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Employer Provided Salary: 190,000-223,000 Annually
Salary data is provided by the employer. Please note this is not a guarantee of compensation.

GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is headquartered in Menlo Park, CA with locations in Washington, D.C., North Carolina, and the United Kingdom. GRAIL, LLC is a wholly-owned subsidiary of Illumina, Inc. (NASDAQ:ILMN). For more information, please visit

Are you a champion of automation interested in using your talents for optimizing processes that will make an impact on the fight against cancer? If so, join GRAIL on the Data Integration team in Research!

GRAIL is seeking a Staff Data Engineer to join our team to support the growing data needs of GRAIL’s clinical and research activities. You will leverage your expertise in automation and data engineering to ensure our scientific teams have the data they need to succeed. This role is pivotal in advancing GRAIL's mission by enhancing our data infrastructure and contributing to our early cancer detection efforts.

This role is located at GRAIL’s headquarters in Menlo Park, CA. It is a hybrid role in which you will work two (2) days a week onsite at headquarters.


  • Be a part of a highly collaborative team that focuses on delivering value to cross-functional partners by designing, deploying, and automating secure, efficient, and scalable data infrastructure and tools, reducing manual efforts and streamlining operations.
  • Help model Grail data and ensure that it follows FAIR principles (findable, accessible, interoperable and reusable).
  • Drive the design, deployment, and automated delivery of data infrastructure, standardized data models, datasets, and tools.
  • Integrate automated testing and release processes to improve the quality and velocity of software and data deliveries.
  • Collaborate with cross-functional teams, from Research to Clinical Lab Operations to Software Engineering to provide comprehensive data solutions from conception to delivery. 
  • Ensure all software and data meet high standards for quality, clinical compliance, and privacy.
  • Mentor fellow engineers and scientists, promoting best practices in software and data engineering.


  • B.S. / M.S. in a quantitative field (e.g., Computer Science, Engineering, Mathematics, Physics, Computational Biology) with at least 8 years of related industry experience, or Ph.D. with at least 5 years of related industry experience.
  • Extensive experience with relational databases, data modeling principles, data pipeline tools and workflow engines (e.g., SQL, DBT, Apache Airflow, AWS GLUE, Spark.
  • Extensive experience with DevOps practices, including CI/CD pipelines, containerized deployment (e.g., Kubernetes), and infrastructure-as-code (e.g., Terraform).
  • Experience with supporting data science / machine learning data pipelines, preferably in the context of analysis of biological data.
  • Experience in developing data pipelines using scalable cloud-based data warehouses / data lakes on AWS, Azure, or GCP.
  • Solid programming skills in object-oriented and/or functional programming paradigms. 
  • Ability to embrace uncertainty, navigate ambiguity, and collaborate with product teams and stakeholders to refine requirements and drive towards clear engineering objectives and designs.
  • A commitment to constructive dialogue, both in giving and receiving critical feedback, to foster an environment of continuous improvement.


  • Prior industry experience in the healthcare, biotech, or life sciences industry, especially in the context of next-generation sequencing.
  • Experience working in a regulated environment (e.g., FDA, CLIA, GDPR).
  • Proficiency in Python, and R.
  • Experience building microservices and web applications.

The estimated, full-time, annual base pay scale for this position is $190,000 - $223,000. Actual base pay will consider skills, experience, and location. 

Based on the role, colleagues may be eligible to participate in an annual bonus plan tied to company and individual performance, or an incentive plan. We also offer a long-term incentive plan to align company and colleague success over time.

In addition, GRAIL offers a progressive benefit package, including flexible time-off, a 401k with a company match, and alongside our medical, dental, vision plans, carefully selected mindfulness offerings.

GRAIL is an Equal Employment Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status. We will reasonably accommodate all individuals with disabilities so that they can participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. GRAIL maintains a drug-free workplace.

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What are GRAIL Perks + Benefits

GRAIL Benefits Overview

We’re committed to creating the best experience for everyone at GRAIL, ensuring that each member of our team has comprehensive benefits and resources to thrive at all stages of life, both at work and at home.

Volunteer in local community
We parter with Bay Area local partners such as Life Science Cares to help meet basic needs in the community.
Partners with nonprofits
GRAIL partners with The Honor Foundation to facilitate mock interviews to help military professionals transition to civilian life. Also oSTEM and The National Sales Network to identify diverse talent.
Open door policy
OKR operational model
Team based strategic planning
Open office floor plan
Employee resource groups
Employee-led culture committees
Hybrid work model
In-person all-hands meetings
Employee awards
Flexible work schedule
Remote work program
Dedicated diversity and inclusion staff
Mandated unconscious bias training
Unconscious bias training is included as part of our standard interview training. We also have a formal training on the topic of unconscious bias that is facilitated by the People Team.
Diversity manifesto
Mean gender pay gap below 10%
Diversity employee resource groups
GRAIL proudly offers 4 employee resources groups led by team members in tandem with an executive sponsor. They include: ASERG, WERG, PRIDE, and BIPOCC.
Hiring practices that promote diversity
GRAIL's Talent team has partnered with a variety of non-profits, associations and job boards including WITI, oSTEM, THF, DiversityJobs and The National Sales Network to identify diverse talent.
Health Insurance + Wellness
Flexible Spending Account (FSA)
Disability insurance
Dental insurance
Vision insurance
Health insurance
Life insurance
Wellness programs
Team workouts
Mental health benefits
Abortion travel benefits
Financial & Retirement
401(K) matching
Company equity
Performance bonus
Pay transparency
Child Care & Parental Leave
Childcare benefits
Generous parental leave
Family medical leave
Company sponsored family events
Fertility benefits
Vacation + Time Off
Unlimited vacation policy
Paid holidays
Paid sick days
Flexible time off
Bereavement leave benefits
Company-wide vacation
Office Perks
Commuter benefits
Company-sponsored outings
Free daily meals
Free snacks and drinks
Some meals provided
Company-sponsored happy hours
Onsite office parking
Recreational clubs
Relocation assistance
Onsite gym
Professional Development
Job training & conferences
Promote from within
Mentorship program
Online course subscriptions available
Paid industry certifications

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