Medical Device Company Calyxo Secures $40M Series F Round

The company’s platform uses minimally invasive techniques to help clinicians remove kidney stones.

Written by Ashley Bowden
Published on Apr. 16, 2026
Doctors looking at tablet
Photo: Shutterstock
REVIEWED BY
Rose Velazquez | Apr 16, 2026

Calyxo, a Silicon Valley-based medical device company, pulled in a $40 million round of Series F funding. Ally Bridge Group and Janus Henderson Investors led the capital raise that enables Calyxo to further grow its CVAC System offering.

The company’s CVAC System is an FDA-cleared solution for minimally invasive kidney stone clearance. The platform leverages irrigation and vacuum aspiration to clear stone fragments during and after laser lithotripsy. Calyxo will invest its Series F in fueling the commercial expansion of this solution, clinical evidence generation and product innovation.

“More than 40,000 patients have now been treated with the CVAC System. Real-world experience, together with an established body of clinical evidence, indicates that the CVAC System is moving beyond early adoption and becoming an important part of the standard of care in kidney stone treatment,” Joe Catanese, Calyxo’s CEO, said in a statement. “This financing allows us to move faster in advancing our technology and expanding the evidence base to further improve patient care.”

Related ResourcesTech & Startup Jobs in San Francisco

Explore Job Matches.