Jobs at GRAIL

Build and own production-grade data systems that transform clinical, lab, and operational data into trusted, analysis-ready datasets. Collaborate with scientists, clinicians, and operations to design data models, services, and workflows enforcing integrity, access control, and regulatory compliance. Lead long-lived systems, improve data quality, monitoring, testing, and mentor engineers while supporting incident response and cross-functional adoption.

Develop and validate predictive models using population-scale genomic and NGS datasets to monitor and improve a multi-cancer classifier. Integrate genomics, DNA methylation, epidemiology, and statistics to identify performance trends, communicate findings cross-functionally, and build reproducible analysis pipelines to support clinical product deployment.

Lead design, development, testing, and deployment of large-scale software systems. Define architecture and best practices, mentor engineers, collaborate with stakeholders, ensure regulatory and security compliance, and drive platform strategy and technical excellence.

Lead design and development of cloud-native full-stack and microservice systems for patient-facing and clinical data platforms. Provide technical leadership, drive cross-functional programs, improve engineering practices, and mentor engineers to deliver robust, scalable software.

Lead product security architecture and security-by-design across the product lifecycle. Embed security into SSDLC and DevSecOps, perform threat modeling and risk assessments, define controls for AI/ML products, manage post-market surveillance, oversee penetration and advanced testing, support incident response, partner with cross-functional stakeholders for regulatory compliance, track security metrics, and mentor other engineers.

The Staff Quality Engineer ensures compliance in quality management systems, leads post-market surveillance, manages complaints, and collaborates cross-functionally to improve quality processes.

Lead and scale a global Data Platform engineering team to deliver a cloud-native, serverless microservices data platform. Define architecture and roadmaps for petabyte-scale data processing, AI/LLM-enabled features (RAG), high-throughput ETL, and secure REST APIs while ensuring CI/CD, DevOps, cost optimization, and regulatory compliance (HIPAA/GDPR).

Maintain and improve Bazel-based build workflows and CI/CD pipelines to boost developer experience and reliability. Own build performance, remote caching/execution, test sharding, and tooling for a multi-language monorepo. Build internal automation, diagnose CI flakiness, support container and Python packaging workflows, and collaborate with developers, researchers, and platform teams to accelerate delivery.

Lead Email/SMS and CRM strategy and execution across B2B, B2C and B2B2C for the Galleri® product. Manage a small team, administer Pardot, Salesforce Marketing Cloud and Paubox, build transactional journeys, optimize deliverability and engagement, run A/B tests and reporting, ensure compliance and data governance, collaborate cross-functionally on attribution and Salesforce reporting, and support technical integrations and documentation.

Design, build, test, deploy, and support AI-enabled software and ML services (including LLMs, RAG, and Generative AI). Integrate models, build APIs and CI/CD, troubleshoot production issues, collaborate cross-functionally, and ensure secure, compliant software in regulated healthcare environments.

Provide corporate and securities legal support for a public company, including SEC filings, governance, capital markets transactions, M&A, executive compensation, investor communications, and cross-functional legal advising. Lead SEC reporting, proxy and board processes, due diligence, and equity program compliance while mentoring junior attorneys and partnering with business teams to manage legal and regulatory risk.

Design, build, test, and maintain scalable backend services and production-grade applications. Collaborate with product managers and engineers, participate in code reviews, troubleshoot and optimize performance, support system reliability and monitoring, and contribute to architecture and documentation in an agile, mission-driven environment.

Lead month-end, quarter-end, and year-end close activities including journal entries, reconciliations, variance analysis, and accruals (including clinical trial accruals). Support SOX compliance and audits, drive automation and AI-enabled process improvements, maintain controls, and partner cross-functionally to ensure accurate US GAAP financial reporting.

Field-based HEOR liaison responsible for communicating and refining health economic, outcomes, and real-world evidence to payers. Support AMCP dossiers, value frameworks, and payer-focused education; partner with Market Access, Medical Affairs, and Commercial teams; identify data gaps, inform research priorities, and represent evidence at regional and national meetings. Requires travel for external engagements and internal collaboration.