Jobs at Lawrence Livermore National Laboratory

Supports enterprise virtual desktop infrastructure and Mission Partner Sites by deploying, configuring, troubleshooting, validating, and sustaining Windows endpoint environments. Diagnoses complex Windows, application, authentication, networking, and configuration issues in Active Directory domains; automates endpoint processes with PowerShell; coordinates projects and change control; maintains documentation; and collaborates with engineering, networking, management, and mission partners. The role requires full-time onsite work, travel up to 50%, and eligibility for a DOE Q clearance.

Provides administrative and operational support for an engineering division. Responsibilities include managing spreadsheets, databases, SharePoint sites, records, calendars, meetings, correspondence, reports, presentations, document compliance, office moves, and a GSA vehicle fleet. The role requires discretion with sensitive or classified information, advanced organizational and communication skills, and the ability to work independently amid changing priorities.

Supports the Biosciences and Biotechnology Division through administrative, operational, organizational, and project coordination. Leads procedures and deliverables, tracks actions, analyzes planning data, prepares management reports, coordinates meetings and events, manages schedules and correspondence, and assists with budget tracking. The role requires strong organization, communication, judgment, stakeholder coordination, and experience with TIME timekeeping and Cvent event management in a classified environment.

Conduct computational structural biology research developing deep learning models to predict protein-protein interactions, specificity, and structure in host-pathogen systems. Build protein sequence and structure analysis frameworks, collaborate with computational and experimental biologists, publish findings, prepare technical reports and briefings, contribute to proposals, and present research at conferences. The role requires independent research in high-performance computing environments and occasional travel.

Conduct research and develop practical AI-enabled tools, agents, and workflows from concept through reliable prototypes. Build reusable components for model access, orchestration, tool use, data integration, and evaluation. Integrate large language models with APIs, databases, and internal systems; assess quality, security, reliability, latency, and cost; and deploy AI services using cloud, containers, and CI/CD practices. Collaborate across technical and business teams to deliver trustworthy, maintainable solutions.

Conduct computational structural biology research focused on predicting protein-protein interactions in host-pathogen systems. Develop bioinformatic tools, protein sequence and structure datasets, and machine learning methods for interaction and structure prediction. Collaborate with computational and experimental biologists, publish findings, present research, contribute to proposals and reports, and travel occasionally to work with external partners and attend conferences.

Conduct research developing integrated electrochemical systems for alternative feedstock conversion and reactive separations. Responsibilities include catalyst and electrolyzer design, electrochemical reactor development, materials synthesis, advanced characterization, modeling, system benchmarking, experimentation, documentation, publications, and collaboration across multidisciplinary teams.

Coordinates research compliance, operational, organizational, and project activities across laboratory offices. Responsibilities include managing audits, records, schedules, procurements, reports, corrective actions, stakeholder communications, and process improvements. The role supports the Select Agent Program, Research Compliance Office, and Central Services while analyzing planning data and maintaining audit readiness.

Leads administrative supervision of a matrixed Project Management group within LLNL’s Strategic Deterrence programs. Responsibilities include personnel management, workforce planning, hiring, onboarding, performance management, employee development, workload coordination, salary planning, and resolving organizational issues. The role partners with technical and organizational leaders to align staffing and capabilities, foster a high-performing team, and address workforce gaps. Higher-level duties include broader talent strategy, mentoring supervisors, influencing organizational structure, and improving administrative processes.

Supports assurance, safety, quality, and regulatory compliance programs for the National Ignition Facility and Photon Science Directorate. Responsibilities include conducting fact-finding and causal analyses, preparing DOE reports, developing corrective actions, coordinating self-assessments and audits, managing issue tracking and trending, and overseeing compliance with DOE, OSHA, ES&H, quality, and Integrated Safety Management requirements.

Design, fabricate, test, and characterize precision hardware and dimensional metrology systems. Develop metrology tools, measurement techniques, uncertainty analyses, point-cloud workflows, and acceptance criteria using optical methods, statistical analysis, MATLAB, Python, and related software. Interpret drawings and GD&T, collaborate with interdisciplinary teams and vendors, document results, and support research, stockpile stewardship, and future technology proposals. The role requires full-time onsite work and eligibility for a DOE Q-level clearance.

Provides electronic technical support for high-explosives experiments, including designing, fabricating, assembling, testing, calibrating, maintaining, and documenting electronic systems. Operates diagnostic equipment, performs data recovery, checks facility controls and interlocks, and supports operational readiness. The senior level adds complex weapons-system assembly, procedure development, advanced system design, and independent problem solving. The role requires onsite work, U.S. citizenship, eligibility for a DOE Q clearance, protective-equipment qualification, and specialized laboratory certifications.

Develops and applies mechanical and manufacturing engineering solutions for national security programs. Responsibilities include component fabrication processes, tooling design, inspection, engineering calculations, process optimization through DoE, data analysis, additive manufacturing, precision engineering, and MES use. The engineer collaborates across disciplines, presents technical plans, develops procedures, and may lead advanced manufacturing technology projects, design reviews, and R&D proposals. The role requires full-time onsite work and eligibility for a DOE Q-level clearance.

Supports computational biology and bioinformatics workflows for biosurveillance, syndromic surveillance, and environmental metagenomics. Responsibilities include developing reproducible pipelines, analyzing and visualizing biological and surveillance data, processing metagenomic sequencing data, using high-performance computing, evaluating approved AI tools, building dashboards, documenting methods, and communicating results in an interdisciplinary research environment.

Lead cybersecurity and applied AI research focused on identifying vulnerabilities, analyzing adversarial behavior, and defending operational technology, industrial control systems, critical infrastructure, and Federal networks. Develop and validate analysis software, AI models, adversarial simulations, and threat-mitigation workflows. Collaborate across disciplines, advise stakeholders, shape technical strategy, mentor staff, and support research proposals and funding. Higher-level responsibilities include directing complex projects, establishing research vision, developing advanced algorithms, and influencing Laboratory-wide technical direction.

Conduct basic and applied research modeling, simulating, and optimizing energy and climate systems. Develop continuum models, HPC algorithms, and custom or commercial simulations for electrochemical systems, energy devices, carbon capture, and advanced manufacturing. Collaborate with multidisciplinary scientists and engineers, pursue independent research, publish peer-reviewed work, and present findings at conferences.

Develop novel correlative microanalytical techniques for nuclear materials forensic characterization using SIMS, electron microscopy, AI/ML, and statistical uncertainty analysis. Conduct independent research, publish findings, present at conferences, and collaborate within multidisciplinary teams. The role requires a PhD, microanalysis experience, Python or similar programming skills, strong experimental design capabilities, and eligibility for a DOE Q-level security clearance.

Leads the ESH project management program and performance measurement capabilities across the directorate. Establishes project standards, governance, training, and coaching; guides complex initiatives; develops integrated performance measures and dashboards; analyzes trends; and advises senior management. The role also drives continuous improvement, cross-functional collaboration, strategic planning, and organizational performance decision-making.

Plans, designs, budgets, and executes equipment recapitalization and infrastructure projects supporting nuclear weapons programs. Develops technical requirements, specifications, cost and schedule plans, safety documentation, and risk controls. Coordinates SMEs, vendors, procurement, contractors, facility operations, and program stakeholders. Leads design reviews, equipment acquisitions, utility installations, project execution, and performance reporting. Higher-level responsibilities include portfolio management, strategic infrastructure planning, prioritization, and advising senior leadership and external sponsors.

Develop, configure, integrate, and support the Laboratory’s on-premises Octave EAM CMMS. Responsibilities include building workflows and interfaces, integrating enterprise systems, migrating and transforming legacy data, troubleshooting operational issues, supporting code migration, and documenting technical solutions. Higher-level responsibilities include designing complex integrations, leading technical approaches, mentoring team members, and coordinating CMMS modernization projects.