Jobs at MSD Animal Health Technology Labs

Design and execute translational PK/PD, PBPK, and QSP analyses integrating in vitro and in vivo data to inform modality selection, dose prediction, and drug discovery. Build mechanistic models and automated workflows, collaborate with cross-functional teams, and contribute leadership in model-informed decision making for biologics, protein therapeutics, and peptides.

Perform MAPPs experiments and immunoaffinity LC-MS workflows to assess immunogenicity. Maintain mammalian cell cultures, prepare samples, operate and troubleshoot Orbitrap LC-MS instruments, document and analyze experimental data, and support workflow optimization and laboratory automation.

Lead translational PK/PD modeling for biologics, proteins, and peptides: build PKPD, PBPK, QSP and mechanistic models, integrate in vitro/in vivo data, guide dose prediction and modality selection, design experiments and automated modeling workflows, and mentor junior scientists across discovery and translational teams.

Lead statistical analyses, build ML models and data pipelines to support early target and drug discovery. Collaborate with bench scientists to analyze diverse biological data, develop agentic AI tools for analysis and visualization, publish results, and contribute to computational infrastructure.

Lead development and deployment of production-grade AI/ML and agentic systems for computational toxicology. Fine-tune foundation models, integrate multimodal datasets, establish MLOps and governance, collaborate with toxicologists and scientists, and ensure explainability, reproducibility, and regulatory-ready practices for preclinical safety assessments.

Lead DMPK strategy for conjugates and novel modalities, advise cross-functional teams from discovery through clinical candidate nomination, oversee LM ADME experimentation, manage and develop a team of scientific leaders, and integrate translational PK/PD and bioanalytical data into regulatory and portfolio decisions.

Lead and execute antibody discovery campaigns using single B-cell workflows (10x Genomics), optimize throughput and timelines, provide scientific leadership on screening and candidate progression, partner cross-functionally, and contribute to scientific visibility through publications and presentations.

Lead scientific and operational bioanalytical strategy across discovery portfolios for biologics, small molecules, conjugates and novel modalities. Oversee assay strategy, method development/validation, data quality, automation and harmonization; manage and develop bioanalytical and DMPK leaders; represent PDMB on cross-functional teams to enable candidate selection, translational interpretation, regulatory readiness, and portfolio decision-making.

Senior leader responsible for strategic, scientific, operational, and people leadership for cardiometabolic clinical development. Oversees clinical science portfolio delivery, regulatory readiness, quality, innovation (AI/advanced analytics), cross-functional collaboration, talent development, and organizational design to drive clinical program execution and long-term capability building.

Senior leader accountable for Clinical Science strategy and delivery across ophthalmology and neuroscience portfolios. Oversees scientific rigor, regulatory readiness, resource allocation, talent development, and adoption of AI/advanced analytics. Partners cross-functionally to drive study execution, regulatory submissions, and organizational capability building while fostering innovation, quality, and continuous improvement.

Senior clinical science leader responsible for strategic, scientific, operational, and people leadership of immunology development programs. Oversees portfolio delivery, regulatory readiness, innovation (AI/advanced analytics), study oversight, talent development, and cross-functional collaboration to drive clinical development outcomes.

Senior clinical science leader accountable for strategy, portfolio delivery, and people leadership across oncology programs (thoracic, lung, head & neck, gastrointestinal). Drives scientific rigor, regulatory readiness, cross-functional collaboration, talent development, and adoption of AI/advanced analytics and digital capabilities to improve decision-making, study oversight, and organizational performance.

Senior leader accountable for clinical science strategy and delivery across oncology portfolios (genitourinary, melanoma, women’s cancers). Oversees scientific rigor, regulatory readiness, talent development, and adoption of AI/advanced analytics while partnering cross-functionally to drive clinical program execution, resource optimization, and organizational capability building.

Senior leader accountable for Clinical Science strategy and delivery across oncology and hematology portfolios. Oversees a large matrixed team, drives scientific rigor, regulatory readiness, adoption of AI/advanced analytics, talent development, cross-functional collaboration, and organizational design to enable successful global clinical development.

Coordinate design, planning and execution of early-phase clinical trials; oversee study conduct, safety assessment, data review, on-site monitoring, regulatory and clinical writing, and cross-functional project management to ensure compliance with GCP/ICH and study objectives.

Lead strategic planning and execution of late-stage clinical development in immunology/dermatology: design and run phase 2/3 trials, evaluate translational data, manage safety/efficacy analyses, support regulatory filings and publications, supervise clinical scientists, and collaborate cross-functionally with regulatory, statistics, and manufacturing teams.

Senior scientific leader who defines pharmacology and translational strategy, advises discovery teams, guides assay/model selection, supports SAR progression and BD&L, mentors scientists, manages portfolio resourcing and dashboards, and drives cross-functional alignment to accelerate preclinical-to-clinical translation across modalities.

Lead discovery research in obesity and metabolic diseases, managing a scientific team to advance targets from identification through preclinical candidate nomination by integrating human biology, translational science, biomarkers, genetics, and cross-functional partnerships.