Top Senior Machine Learning Engineer Jobs in San Francisco, CA

Lead camera ISP tuning and image quality evaluation for autonomous vehicle cameras. Collaborate with cross-functional teams and vendors to define specs, characterize sensors, develop ISP configurations, run objective/subjective IQ tests (Imatest), and optimize ISP for perception performance in production vehicles.

Develop and deploy machine learning and LLM capabilities for agentic search, query understanding, search planning, and retrieval. Build evaluation datasets, improve model behavior through experimentation and fine-tuning, and optimize quality, latency, cost, and reliability. Collaborate across search, product, infrastructure, and AI teams while owning projects through production and mentoring engineers.

Develop and deploy scalable machine-learning solutions, particularly deep-learning forecasting models for company top-line metrics. Lead the full ML lifecycle from problem definition and experimentation through production deployment and improvement. Design production-grade architectures, evaluate and improve models, collaborate with cross-functional teams, explain technical concepts to varied audiences, and mentor junior engineers.

Design, build, and support high-throughput, low-latency LLM inference and data pipelines; collaborate with data scientists to post-train and evaluate models; implement scalable, production-ready systems with strong testing, monitoring, and performance focus; mentor engineers and iterate on architecture, reliability, and user-facing AI applications.

Own the architecture and evolution of W&B ML workflow systems, including backend services, APIs, SDKs, and frontend components. Design scalable systems, lead live-traffic migrations, resolve complex cross-service issues, reduce technical debt, and improve reliability. Collaborate with product, design, customers, and ML platform teams to deliver workflow solutions. Mentor engineers and establish scalable engineering practices across distributed systems, data platforms, APIs, event-driven infrastructure, or full-stack development.

Leads the technical direction, architecture, and roadmap for agentic machine learning systems processing global trade data. Builds ingestion, document understanding, entity resolution, inference, evaluation, observability, and feedback systems. Adapts and post-trains LLMs, ships production AI agents, mentors engineers, sets technical standards, and partners with product, engineering, data science, and customers to deliver risk, compliance, and enforcement capabilities.

Design, build, deploy, and optimize large-scale machine learning models and infrastructure for Uber Maps, including high-throughput, low-latency prediction systems and APIs. Develop distributed ML pipelines, improve routing and ETA applications, explore optimization solutions, and provide technical leadership. Collaborate with product managers, scientists, designers, and engineers to solve complex, real-world mobility problems.

Develop and improve reliable LLM and deep learning capabilities, build scalable real-time machine learning models, advance Responsible AI practices, and define technical strategies for deep learning, RAG, and LLMs. Collaborate with AI scientists and engineers, conduct ML and reinforcement learning research, fine-tune models, and drive adoption of AI best practices across service teams.

Build and own production machine learning infrastructure for growth initiatives, including feature pipelines, point-in-time-correct training data, batch inference, model registries, retraining automation, validation safeguards, and production monitoring. Partner closely with data science and data engineering to productionize models, prevent data leakage and train-serve skew, and ensure reliable model-driven promotions.

Build and operate scalable machine learning systems for personalized recommendations, growth journeys, cross-product expansion, and sales experiences. Design models, datasets, features, evaluation frameworks, and decisioning services; run offline policy evaluations and online experiments; and monitor attribution, latency, quality, and fairness. Partner with product, engineering, data science, analytics, marketing, and sales teams to turn ambiguous growth opportunities into measurable production capabilities and strategic ML initiatives.

Lead the design, development, deployment, and optimization of production machine learning systems for search, recommendations, personalization, NLP, deep learning, and AI applications. Own projects across the full ML lifecycle, design scalable architectures and evaluation strategies, collaborate with product and engineering teams, translate research into reliable systems, and mentor other engineers.

Build and operate scalable machine learning systems for Atlassian’s Growth organization, including personalized recommendations, ranking, decisioning, experimentation, and customer journey optimization. Partner with product, engineering, data science, analytics, marketing, and sales teams to translate growth opportunities into measurable production capabilities. Develop datasets, features, models, evaluation frameworks, and monitoring systems while optimizing for customer value, fairness, quality, and long-term business outcomes.

Develop and productionize machine learning systems for search, retrieval, ranking, recommendations, conversational experiences, and AI agents. Own projects across the ML lifecycle, build evaluation datasets and benchmarks, conduct offline and online evaluations, analyze model quality, and improve system performance. Design scalable architectures addressing reliability, latency, privacy, and cost. Collaborate across product and engineering teams, communicate technical decisions, mentor engineers, and contribute to ML best practices.

Architect and build scalable engineering systems while developing and optimizing machine learning models for Uber’s delivery marketplace. Lead organization-wide frameworks and engineering projects, solve low-latency and high-correctness problems, oversee incident management, and collaborate with Product, Science, and Operations. Mentor engineers, drive technical roadmaps, improve developer velocity, and support reliable systems at global scale.

Develop and productize machine learning prediction systems for autonomous driving. Responsibilities include designing end-to-end prediction solutions, researching deep learning models, supporting diverse driving environments, prioritizing data collection and labeling, using simulation and augmentation, and meeting safety, latency, and software robustness requirements. The role also involves collaboration with data teams and deployment of real-time ML solutions to embedded platforms.

Build and lead production machine learning and evaluation systems for Atlassian’s Rovo AI agents. Responsibilities include developing datasets, simulations, automated judges, experimentation platforms, and quality signals; advancing reasoning, planning, retrieval, memory, and tool use; identifying and correcting systemic failures; and balancing quality, safety, latency, reliability, and cost. The role requires hands-on technical leadership, cross-functional influence, architectural decision-making, mentorship, and delivery of measurable customer outcomes at scale.

Leads the technical direction and execution of a machine learning team focused on personalization, relevance, ranking, search, and advertising. Designs, scales, and operates production ML systems, including training, evaluation, deployment, and serving infrastructure. Partners with product, data, and engineering stakeholders, drives architecture and system design decisions, mentors engineers, and uses AI tools to accelerate development and explore LLM-powered features.

Lead the design, development, deployment, and operation of machine learning models and platforms at scale. Build distributed ML infrastructure, data pipelines, cloud-based architectures, and production services. Develop and test application code, automate deployment, monitor and retrain models, and apply CI/CD, governance, security, and responsible AI practices. Collaborate with Product, Data Science, and Agile teams to solve complex business problems.

Design, train, and deploy scalable ML models (generative, classification, regression). Define feature roadmaps, collaborate with engineering to implement code and APIs, adapt ML methods for distributed/GPU environments, and create evaluation/annotation programs for fine-tuning and performance measurement.

Build and improve machine learning systems for ad ranking, relevance, personalization, and optimization. Responsibilities include feature pipelines, model training and evaluation, active learning, LLM-assisted labeling and synthetic data generation, experimentation, and low-latency production inference. The role partners with product, data, and platform teams to improve advertiser performance and user engagement while maintaining reliability, latency, and data quality.

Develop and productize deep learning perception systems for autonomous driving, including traffic signal, sign, road marking, and construction object understanding. Lead end-to-end model development, data-driven improvement, simulation, augmentation, and deployment to embedded platforms. Optimize solutions for accuracy, safety, latency, robustness, and regional generalization while collaborating with data-labeling teams and contributing technical leadership.

Design, train, deploy, and operate machine learning systems for real-time suspicious-activity detection. Own model development, data pipelines, serving, infrastructure, scalability, and production measurement. Collaborate with technical leadership and customers to identify threats and improve detection signals. Establish engineering standards, ensure correctness, and deliver reliable systems in a high-autonomy, fast-moving team.

Supports payer modernization and health services consulting engagements by analyzing operational challenges, optimizing processes, applying business analytics, engaging stakeholders, implementing quality standards, and guiding transformation initiatives. Develops operational support frameworks, conducts market research, manages change, and advises clients on improving service delivery and business performance while mentoring junior team members.

Build and deploy scalable AI and machine learning products for clinical research, including patient recruitment, enrollment forecasting, and study feasibility. Develop ML models, LLM-powered agents, data pipelines, and MLOps infrastructure using cloud services and CI/CD automation. Collaborate with cross-functional teams to integrate AI into clinical research workflows, monitor model performance, and advance reliable, unbiased solutions that improve patient outcomes.

Design and deploy production recommendation and retrieval engines, build data orchestration pipelines for multiple modalities, implement agentic workflow frameworks, and prototype, optimize, and scale models with monitoring, governance, and low-latency SLAs.