Top Chief of Staff Jobs in San Francisco, CA

Serve as a strategic partner to senior leadership to develop and implement short- and long-term programs, manage prioritization and cross-functional dependencies, drive organizational change and operational excellence, create executive-ready presentations, influence matrixed stakeholders, and lead sensitive, complex initiatives with minimal direction.

The Chief of Staff will lead strategic initiatives for new business lines at Atticus, focusing on client acquisition and operational strategy while collaborating with various leaders.

Senior operator to the CMO who designs and runs the marketing operating system for a 300+ person global org. Owns meeting cadence, workback plans, risk management, cross-functional alignment, budget and headcount governance, executive communications, and milestone tracking. Acts as CMO representative, brokers resolution across functions, and partners on strategic initiatives to scale marketing with speed and discipline.

Partner with the CPO and CTO to run R&D operations: lead operating cadence, OKR alignment, reporting/dashboards, budget governance, and cross-functional strategic initiatives. Triage escalations, drive org design and AI-operating-model projects, and draft executive and board communications to enable prioritized, data-driven R&D decision making.

Serve as the CEO's right-hand, managing their time and communications, driving strategic planning, owning cross-functional projects, building accountability systems, drafting executive materials, and executing organizational priorities to ensure follow-through and operational efficiency.

The Chief of Staff/Strategic Finance role involves financial modeling, identifying bottlenecks in business pipelines, and managing strategic initiatives across the company. Responsibilities include goal setting, running reviews, and managing board meetings.

The Chief of Staff, Fusion Sales drives operational excellence and organizational alignment within the Fusion Sales team, providing strategic partnership and executing key business initiatives across the global organization.

Serve as strategic and operational advisor to the COO/CPE, aligning enterprise priorities, managing operational cadence, stakeholder communications, and strategic planning. Oversee execution of major initiatives, synthesize information for leadership, drive operational performance, and enable executive effectiveness across a large, matrixed healthcare system.

Serve as the CEO's strategic partner and operational lead, driving cross-functional initiatives, managing executive office operations, external partnerships, communications, resource development, public affairs, and event execution to advance organizational strategy and community health impact.

Partner with the CPO to translate strategy into operating action, drive cross-functional execution, manage high-priority special projects, run product management rhythms, surface risks and dependencies, improve meeting and escalation discipline, and represent the CPO in internal forums to ensure alignment and delivery during reorganization.

The Chief of Staff will support the founder by designing automated workflows, managing strategic operations, and leading the company’s exit from stealth mode at a venture-backed startup focused on AI autonomy.

The Chief of Staff to the CPO will manage operational excellence and strategic alignment in HR, leveraging AI to improve efficiency and decision-making.

The Chief of Staff/Business Operations Manager will drive strategic initiatives, optimize processes, and collaborate with executives to achieve company objectives.

The Chief of Staff will support the CEO by prioritizing company initiatives, driving cross-functional projects, and ensuring leadership alignment in a fast-paced environment.

The Chief of Staff will partner with the CEO on strategic priorities and oversee cross-functional initiatives, ensuring alignment, accountability, and operational excellence throughout the organization.

The Chief of Staff will assist the CEO in strategic priorities, drive sales and product operations, manage investor relations, and oversee internal initiatives, ensuring organizational excellence and scaling efforts.

Senior leader who partners with the CEO to translate strategy into execution across functions. Leads enterprise strategic planning, performance management, data-driven accountability, cross-functional alignment, executive team effectiveness, and CEO support to ensure measurable outcomes and organizational alignment.

Partner with leadership to drive cross-functional execution, coordinate customers/hiring/operations, maintain follow-through on priorities, improve onboarding and processes, and act as an on-site general-purpose operator in a fast-paced startup.

Partner with founders as a strategic operator to design and scale company foundations, build internal AI agents and workflows, lead end-to-end special projects across product, recruiting, and GTM, and act as an executive proxy to drive high-priority initiatives in a fast-moving, 0-to-1 startup.

Partnering with the CEO, the Chief of Staff drives strategic planning, executive communications, KPI dashboards, cross-functional projects, fundraising support, hiring, and administration to enable organizational priorities and execution.

The Chief of Staff will support the CEO by managing strategic planning, operational coordination, and internal communication. Responsibilities include run exec meetings, oversee initiatives, and prepare key investor updates.

The Chief of Staff will oversee business operations, lead strategic projects, support customer deployments, and address challenges to achieve company goals.

The Chief of Staff will design and execute strategic projects, support the CEO in go-to-market strategies, drive execution across teams, and manage operational systems.

The Chief of Staff manages daily operations, engages with partners, coordinates the team, and leads special projects, ensuring effective execution and alignment across the company.

The Chief of Staff to the CEO will advise on strategic decisions, drive operational efficiencies, and oversee cross-functional initiatives, leveraging AI and automation. This role requires high-level communication and analytical skills, particularly in a tech environment.