Top Chief of Staff Jobs in San Francisco, CA

Run operations for an AI community and conference business while supporting an early-stage venture fund. Own operating plans, metrics, budgets, forecasts, P&L, sales, marketing, event production, partnerships, and cross-functional execution. Translate founder priorities into action, prepare decisions, close follow-up loops, and drive ambiguous projects from concept through completion. The role is broad, in-person, and designed to develop into broader operating leadership.

Chief of Staff to the Chief Content Officer, responsible for translating company strategy into operating systems, driving planning and governance, overseeing strategic projects, enabling cross-functional alignment, supporting executive decision-making, leading engagement and communications initiatives, and improving organizational performance across the Content organization.

Founding Chief of Staff responsible for building Oath Technologies’ early operational infrastructure. Duties include coordinating with the fiscal sponsor, managing budgets and finances, establishing systems, leading hiring and onboarding, handling people operations, administering vendors and partners, and preparing board and stakeholder materials. The role works closely with the CEO and is expected to grow into Head of Operations or COO-level leadership as the organization expands.

Serve as an extension of the CEO and own company operating cadence, including OKRs, leadership meetings, decision logs, and action-item follow-through. Manage commercial and fundraising follow-up, investor updates, board preparation, hiring operations, vendors, compliance, office needs, and other unowned priorities. The role is in person in San Francisco Monday through Thursday, includes travel, and is designed to develop into a senior operational or executive-operations leadership position.

Volunteer Chief of Staff supporting Co-Executive Directors with strategic planning, OKRs, organizational alignment, stakeholder communications, program evaluation, fundraising, and execution. The role coordinates cross-functional teams, develops action plans for political data initiatives, monitors political strategy and major races, prepares leadership meetings and external engagements, reviews team output, and provides status reporting. Requires 8–12 volunteer hours weekly, primarily during work hours, and is remote within the United States.

Chief of Staff supporting the CEO by running leadership operating cadences, planning, reporting, board and investor communications, and cross-functional special projects. The role also maps internal workflows, builds and deploys AI agents using Claude, HubSpot, APIs, and company data, establishes automation standards, and drives adoption across functions. Candidates need strong analytical, writing, systems-thinking, judgment, and execution skills, with 4–8 years of relevant experience.

Partners with the EVP of Consumer and Business Services to translate strategy into action, prepare executive briefings, orchestrate customer and industry engagements, coordinate leadership priorities, and drive cross-functional initiatives. The role requires executive storytelling, strategic synthesis, strong relationship-building, operational discipline, discretion, and the ability to influence across a complex organization.

Partner with the CEO to drive the company’s highest-priority initiatives from strategy through execution. The Chief of Staff will lead cross-functional projects, support company planning and operating rhythms, analyze business challenges, prepare board and fundraising materials, assist with executive hiring, and temporarily own initiatives until a long-term owner is established.

Leads strategy and operations for the CTO Office, translating technology priorities into roadmaps, investment plans, governance mechanisms, operating models, and measurable outcomes. Partners with senior leaders across technology, product, finance, risk, operations, and HR to align resources, resolve execution barriers, manage strategic initiatives, and improve organizational effectiveness. Develops executive decision materials and represents the CTO Office across enterprise forums.

Serve as a strategic partner and force multiplier to the Founder/CEO. Manage executive priorities, represent the CEO, drive ELT operating cadence and cross-functional alignment, prepare leadership and board materials, lead high-impact special projects, and implement AI tools to improve productivity. The role requires exceptional communication, analytical problem-solving, discretion, resilience, organization, and the ability to operate effectively in ambiguity.

Chief of Staff serving as the Founder and CEO’s strategic partner. Responsibilities include managing venture fundraising and investor relations, preparing board materials, leading cross-functional initiatives, improving organizational processes, preparing executive meetings, and drafting internal and external communications. The role requires strong consulting and startup operating experience, fundraising knowledge, AI literacy, exceptional writing, emotional intelligence, and comfort working in complex, fast-changing environments.

Partners with the Chief People Officer and People Leadership Team to execute strategic priorities, manage the People portfolio, oversee planning and budgets, prepare executive and Board materials, facilitate leadership offsites, coordinate engagement events, and lead confidential strategic initiatives.

Partner with the COO and exec team to translate strategy into plans, run leadership and planning cadences, lead cross-functional projects, prepare board/investor materials, define and track OKRs, and build processes to close organizational gaps.

Serves as a strategic partner to the CEO, leading cross-functional initiatives, launching growth opportunities, building management and reporting routines, and removing obstacles for business unit leaders. Requires strong analytical, financial modeling, executive communication, and AI automation skills. The role is based onsite in San Francisco and involves 10–30% travel, with potential progression to business unit leadership.

Work closely with the CEO to manage company priorities, planning and review routines, board and investor materials, and cross-functional initiatives. Lead projects across fundraising, recruiting, operations, sales, product, finance, and partnerships. Connect product, engineering, and go-to-market teams, identify issues early, and build durable processes that resolve recurring problems.

Lead strategic and operational execution for Databricks’ Marketing organization as advisor to the CMO. Translate company strategy into marketing plans, OKRs, and initiatives; improve AI transformation, ROI, analytics, planning, and organizational efficiency; manage CMO leadership forums, executive presentations, communications, and cross-functional priorities across a 250-person team.

Serve as strategic partner to the Global Head of Sales by preparing executive and board materials, facilitating decisions, aligning cross-functional teams, leading sales planning and reporting, analyzing growth opportunities, and driving the sales organization’s operating rhythm. Lead global sales strategy initiatives, executive communications, meetings, offsites, and projects across GTM, Finance, People, Legal, and product teams.

Chief of Staff partners directly with the CEO to scale the company, lead operational initiatives, establish planning and meeting systems, improve execution, support customer and investor growth, and drive high-priority cross-functional projects. The role combines strategic analysis, founder partnership, operational ownership, and relationship management, with success measured by reliable execution and increasing organizational scalability.

Two-year executive leadership program partnering with operating leaders, CEOs, and functional teams across vertical software companies. Own cross-functional value-creation initiatives spanning go-to-market, sales, marketing, pricing, customer success, finance, M&A integration, and business operations. Support executive decision-making, implement operating improvements, and help newly acquired companies establish priorities and operating rhythms. High performers may advance into CEO, C-suite, or headquarters leadership roles.

Leads as strategic advisor and operational partner to the SVP of the Enterprise Customer Group. Manages operating models, executive meetings, strategic planning, business metrics, cross-functional initiatives, change management, and employee engagement. Acts as an executive proxy, facilitates leadership alignment, drives operational excellence, and supports data-driven decision-making across the organization. The role is hybrid in San Francisco with up to 50% global travel.

Supports the CEO and Chief of Staff across hiring pipeline management, executive scheduling, investor and partner communications, vendor and manufacturing coordination, contract administration, cap table and board materials, content creation, partnerships, and event logistics. The intern owns fast-moving workstreams, turns incomplete tasks into plans, and helps coordinate operations during the company’s first large-scale robot production run.

Serve as the CEO's strategic and operational right hand at an AI LegalTech startup: prepare executive/board/investor materials, build financial models and decks, contribute litigation expertise to product content, validate LLM-generated analyses, drive cross-functional execution, manage company operations (recruiting, vendor administration, OKRs), represent the CEO, and handle special projects across finance, legal, and partnerships.

Leads as strategic partner and operational integrator to the CFO, coordinating financial planning, budgeting, forecasting, executive communications, board and investor materials, cross-functional initiatives, and Finance’s operating cadence. Drives accountability, operational efficiency, financial transformation, cost optimization, and enterprise alignment while advising senior leaders and supporting high-priority projects across Finance and the broader organization.

Chief of Staff partnering with the CEO and founding team to drive company priorities, cross-functional initiatives, operating rhythms, fundraising support, metrics analysis, process improvement, hiring, and execution. The role operates across product, go-to-market, operations, and strategy in a remote, early-stage AI-native legal services company.

Serve as a force multiplier for the founders across go-to-market, operations, and strategy. Build and close sales pipeline through outbound, conferences, referrals, and partnerships; translate customer feedback into product decisions; prepare investor and partner conversations; and own internal administrative initiatives. The role requires startup operating experience, AI fluency, proven 0-to-1 go-to-market execution, strong communication, decisive problem-solving, and a high bias toward action.