San Francisco has long been a hub for tech, fueled by the energy of nearby Silicon Valley, but the city can’t afford to rest on its reputation. To remain at the forefront of innovation, established companies must keep pushing boundaries as new startups emerge with fresh ideas.
Now more than ever, these companies are actively hiring local talent to stay competitive and continue driving innovation.
These are the one to know.
Top Companies Hiring Machine Learning Engineers in San Francisco
- Mastercard
- Celonis
- SoFi
- PwC
- Block
Companies Hiring Machine Learning Engineers in San Francisco
Superhuman offers tools that assist individuals and businesses with writing, from grammar checking to content generation. In 2025, the company rebranded from Grammarly to highlight its expansion into AI productivity tools and is now focused on growing its machine learning team to advance AI capabilities for its users.
DigitalOcean’s cloud platform is designed to provide reliable, cost-effective infrastructure for AI applications. The company has job opportunities for software engineers who bring artificial intelligence and machine learning expertise and can work both independently and collaboratively to support large cross-functional projects.
Mastercard, headquartered in Purchase, New York, enables secure digital payments through its network of credit, debit and prepaid cards. According to the company, it is currently growing its data and AI teams and has several machine learning roles open at its Mission Street office in San Francisco.
PwC provides a broad range of professional services, from audit and assurance to tax and consulting, designed to help organizations strengthen trust and support sustainable growth. As one of the Big Four accounting firms, it is currently recruiting for multiple hybrid and on-site roles at its office near Salesforce Park.
Coinbase has developed a secure platform for cryptocurrency trading. Its technology allows individuals, businesses and institutions to engage with crypto assets. The company is recruiting for its machine learning team. Its available opportunities include a 12-week engineering internship program based in San Francisco.
Block is a global financial technology company with deep involvement in blockchain and cryptocurrency, leveraging its family of subsidiaries to expand access to the global economy. Its regional headquarters are located in nearby Oakland, just across the Bay from San Francisco.
Samsara specializes in IoT solutions that provide businesses with actionable intelligence across complex physical operations. The San Francisco-based company is hiring senior and staff machine learning engineers to work on AI systems that power real-time safety and efficiency insights for frontline industries.
Celonis uses process mining and AI to build a digital twin of a company’s end-to-end processes, giving organizations clearer insight into how their operations run and where they can improve efficiency, cash flow and customer experience. The company, founded in 2011, is headquartered in NYC with offices around the world. Among its U.S. locations, the company maintains a Bay Area office in Redwood City.
VSCO allows both casual and professional users to edit photos and videos using free or paid memberships, with access to presets, filters and a community of creators to share their work. The company’s regional office is located at 340 Pine Street, just blocks from One Market Plaza.
Toast’s platform combines SaaS products and financial technology solutions to support efficiency across restaurant and retail operations. Software engineers at Toast aim to solve real-world problems and expand the company’s product portfolio by collaborating on machine learning and artificial intelligence solutions.
Adyen enables businesses to accept and process payments online, in-app and in person, while also managing the full payments lifecycle across credit cards, digital wallets and a wide range of other methods. The company is currently growing its AI team in San Francisco and is hiring for several hybrid roles.
General Motors designs, manufactures and sells cars, trucks and automotive parts, while also providing financing services. With a global footprint spanning 30 offices, GM’s Silicon Valley location is currently hiring for a variety of engineering roles.
Cash App enables millions of users to manage their finances, offering peer-to-peer payments, direct deposits, stock investing and more. While the company’s parent company, Block, is headquartered in Oakland, Cash App operates several teams from its San Francisco office on Market Street.
SoFi delivers a unified digital platform for banking, lending and investing, serving both individual consumers and businesses. It also supports external companies by offering tools to build and manage their own financial products, and maintains a San Francisco headquarters at its 234 1st Street office near Salesforce Park.
Gusto delivers a comprehensive portfolio of HR, benefits and payroll solutions for small and medium-sized businesses across industries like retail, healthcare, construction and manufacturing. The HR tech company is expanding its team of machine learning and applied AI engineers.
