Teams at BigHat Biosciences

Support R&D to advance phage and yeast display technologies for antibody discovery. Construct and QC display libraries, perform selections, express/purify/characterize molecules (ELISA, flow cytometry, BLI/SPR, CE-SDS), analyze results, collaborate with Data Science/ML on library design and model training, present results, and maintain records in LIMS and electronic notebooks.

Hands-on, bench-driven role to design, optimize, and execute high-throughput antibody developability assays. Drive developability assessments, support late-stage characterization and IND-enabling studies, lead project experimental strategy, automate and integrate methods with LIMS, analyze data, and communicate findings across teams.

Lead end-to-end development and ownership of major areas of an internal cloud-based platform supporting antibody discovery. Translate lab workflows into reliable software, design system-level architecture, implement front-end and back-end features, improve testing and engineering practices, and collaborate with scientists and product owners to deliver validated production systems.