Own the full accounting function for a high-growth biotech, including financial close, reporting, technical accounting, R&D accruals, tax, equity accounting, compliance, and audit readiness. Build scalable finance infrastructure, internal controls, and SOX compliance processes while leading a NetSuite implementation and transition from QuickBooks. Prepare board reporting, manage external advisors and auditors, support public-company reporting, implement finance automation, and build an effective accounting team.
The role: BigHat Biosciences is seeking a detail-driven, proactive, and analytical Controller to serve as BigHat’s senior accounting leader and architect of its finance infrastructure at a pivotal stage of growth. This role is for someone who enjoys solving complex accounting challenges, focuses on continuous process improvements, thrives in a fast-paced environment, and is a true builder. You will own the full accounting function, from close and financial reporting to technical accounting, equity, tax and compliance. You’ll also be designing and/or improving the systems, controls, and processes required for a future public-company operating environment.
The right candidate brings accounting experience from a high-growth biotech, pharma or life sciences company (with exposure to CRO accruals and R&D program cost tracking), hands-on NetSuite (or similar) implementation or migration experience, and the technical rigor to independently research and document complex GAAP positions. You are comfortable serving as the primary interface with external auditors, capable of building an internal Sarbanes-Oxley (SOX) Compliance control framework from the ground up, and ready to lead the company's transition off QuickBooks as we scale.
Key Responsibilities
- Serve as BigHat's in-house technical accounting authority; research and prepare position memos on complex transactions, new GAAP pronouncements, and company-specific accounting policy decisions, analyzing and communicating risks and benefits effectively.
- Executes general ledger operations, leading financial close process to ensure accurate and timely US GAAP financial statements.
- Drive R&D accounting across CRO and vendor accruals, prepaids, and program-level cost tracking, bringing structure and visibility to one of the company's largest spend categories.
- Build and deliver financial reporting packages and board-level management decks; translate financial results and key metrics into clear narratives for executive leadership and the Board.
- Design, implement, and maintain a SOX compliance internal control framework scaled for a high-growth company, balancing rigor with operational practicality as the company grows.
- Lead audit readiness; drive clean, timely delivery of annual financial statement audits in accordance with GAAP.
- Manage federal, state, and local tax compliance in coordination with external advisors; lead R&D tax credit studies and other R&D-related tax matters.
- Evaluate and implement AI-enabled tools and finance technology, including procure-to-pay and close management tools, to reduce manual effort, improve auditability, and strengthen data integrity at scale.
- Own payroll administration and equity accounting and plan administration under ASC 718 (including stock-based compensation expense, 409A valuation support, cap table integrity, and related financial statement disclosures).
- Own NetSuite ERP implementation including processes and controls while maintaining segregation of duties.
Skills Knowledge and Expertise
- Bachelor's or Master's in Finance, Accounting or Business preferred. Active CPA license.
- 10+ years of professional experience in accounting, including 3+ years of experience in a public biotech company.
- Prior Controller or Assistant Controller experience at a venture-backed biotech or life sciences company strongly preferred.
- Strong command of US GAAP and technical accounting standards.
- Big 4 audit experience.
- Hands-on public company reporting experience; have personally prepared or reviewed Forms 10-Q and 10-K at a public company.
- Experience with CRO/CDMO contract accounting and accrual estimation.
- Hands-on experience with NetSuite or a comparable ERP, including comfort operating through a system migration.
- Familiarity with SOX/ICFR build-out in a pre-IPO environment.
- A track record of embedding AI tools to accounting and finance workflows.
- Experience managing and transitioning outsourced accounting or consultant relationships in-house.
- Demonstrated success in building and managing teams to achieve financial and business goals.
- Excellent communication skills, both written and verbal, with the ability to convey complex information to diverse audiences.
- Comfort with uncertainty and demonstrated ability to exercise sound judgment under tight timelines and independently determine appropriate action where precedent may not exist.
- Detail-oriented and results-driven with bias for action and sense of urgency.
- Ability to work in a fast-paced environment with high expectations and ability to effectively manage multiple competing priorities effectively.
- Strong project management skills and experience managing multiple vendors and external partners.
- Strong interpersonal and communication skills to influence, collaborate, resolve conflicts, and build consensus with diverse stakeholders.
Total Rewards
The salary estimated for this position is $240,000 - $301,000 + bonus + options + benefits. Compensation will vary depending on job-related knowledge, skills, and experience. Actual compensation will be confirmed in writing at the time of the offer.
About
BigHat Biosciences designs safer, more effective biologic therapies for patients using machine learning and synthetic biology. BigHat integrates a wet lab for high-speed characterization with machine learning technologies to guide the search for better antibodies. We apply these design capabilities to develop new generations of safer and more effective treatments for patients suffering from today’s most challenging diseases.BigHat is a Series B biotech outside San Francisco with a team-oriented, inclusive, and family-friendly culture. Our broad pipeline of wholly-owned and partnered therapeutic programs span many disparate indications with high unmet need, such as cancer, inflammation, and infectious disease. BigHat has raised >$100M from top investors, including Section 32, a16z, and 8VC.
BigHat Biosciences San Mateo, California, USA Office
1900 Alameda de Las Pulgas, San Mateo, CA, United States, 94403
Similar Jobs
Healthtech • Pharmaceutical
Leads global financial reporting, internal controls, planning, forecasting, pricing, procure-to-pay, sales and operations planning, finance transformation, and investor relations for AbbVie’s Allergan Aesthetics business. Oversees finance operations, audit coordination, governance reviews, systems improvements, and executive-level financial deliverables. Manages approximately 30 professionals, including eight direct reports, while partnering with corporate finance, commercial, manufacturing, supply chain, and business leadership.
Top Skills:
Desktop Productivity SoftwareGaapMainframe Accounting ApplicationsSap Analytics Cloud (Sac)Sox
Biotech
Lead the accounting organization through monthly, quarterly, and annual close, audits, financial reporting, internal controls, tax coordination, and complex biotech accounting. Build scalable processes, systems, and controls for an IPO-track company; manage outsourced providers; oversee clinical and R&D accruals, treasury, equity, and ERP workflows; and develop the accounting team while partnering with Finance leadership, auditors, and cross-functional stakeholders.
Top Skills:
Close-Management SoftwareEquity-Administration SoftwareErp SystemsNetSuiteSec-Reporting Software
Information Technology • Software
Lead and scale global controllership and accounting operations including monthly close, financial statements, technical accounting (US GAAP/IFRS), intercompany and international accounting, AP/payroll/equity administration, SOX readiness, and external audits. Drive ERP and systems improvements, process and AI automation, KPI reporting, and mentor a high-performing team while partnering cross-functionally to support a high-growth SaaS business.
Top Skills:
AIErpNetSuite
What you need to know about the San Francisco Tech Scene
San Francisco and the surrounding Bay Area attracts more startup funding than any other region in the world. Home to Stanford University and UC Berkeley, leading VC firms and several of the world’s most valuable companies, the Bay Area is the place to go for anyone looking to make it big in the tech industry. That said, San Francisco has a lot to offer beyond technology thanks to a thriving art and music scene, excellent food and a short drive to several of the country’s most beautiful recreational areas.
Key Facts About San Francisco Tech
- Number of Tech Workers: 365,500; 13.9% of overall workforce (2024 CompTIA survey)
- Major Tech Employers: Google, Apple, Salesforce, Meta
- Key Industries: Artificial intelligence, cloud computing, fintech, consumer technology, software
- Funding Landscape: $50.5 billion in venture capital funding in 2024 (Pitchbook)
- Notable Investors: Sequoia Capital, Andreessen Horowitz, Bessemer Venture Partners, Greylock Partners, Khosla Ventures, Kleiner Perkins
- Research Centers and Universities: Stanford University; University of California, Berkeley; University of San Francisco; Santa Clara University; Ames Research Center; Center for AI Safety; California Institute for Regenerative Medicine



