Associate Scientist I/II, Formulation & Process Development

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.

We are currently searching for a highly motivated Associate Scientist I/II to join our Formulation and Process Development team. In this role, you will directly work on formulation and process development of our cutting-edge CAR-tLNP drug product to support emerging research pipelines focused on immunology, oncology, fibrosis and inflammation-related diseases, and blood monogenic disorders.

This position will report to a Scientist II, Formulation and Process Development, and is based at our San Diego office. This role will involve hands-on laboratory work. All duties will be performed in compliance with AbbVie’s standard operating procedures (SOPs).

Responsibilities:

• Prepare, formulate, and characterize complex, nucleic acid-based lipid nanoparticle formulations in a consistent, reproducible manner.
• Fulfill varied production requests from internal teams to support various ongoing drug product pipelines.
• Develop the formulation and purification process for lipid nanoparticle based nucleic acid formulations with targeting modalities, including high-throughput processes.
• Perform investigations of aberrant results, determine the root cause(s), and recommend an action plan to ensure process robustness.
• Maintain proper documentation of all experimental procedures and results, including batch records, protocols, Standard Operating Procedures (SOPs) and other manufacturing related documentation.
• Prepare and present technical reports and presentations which summarize procedures, study results, and data interpretation as needed.
• Collaborate within the formulation team, as well as with other functional teams, to deliver high quality results in an accurate and time sensitive manner.

All other tasks and duties assigned as perceived and agreed upon by management.

• Associate II: Bachelor’s Degree, or equivalent education, with typically 3 or more years’ experience or Master’s Degree or equivalent education (no additional experience)
• Associate I: Bachelor’s Degree (no additional experience)
• Degree in Chemistry, Pharmaceutical Sciences, Biochemistry, Chemical Engineering, Bioengineering or other related fields preferred.
• Experience with lipid nanoparticle formulation and purification processes, or experience with process development engineering and manufacturing of biologics drug product processes, are highly desired.
• Hands-on experience working with nucleic acid and/or lipid nanoparticle-based formulations, complex/nanoparticle formulations, or other biological formulations.
• Working knowledge of tangential flow filtration or other purification processes is preferred.
• Ability to work in a well-lit heated and/or air-conditioned indoor office and laboratory setting with adequate ventilation. Light physical activity performing non-strenuous daily activities of a productive/technical nature. May require long periods of standing/sitting.
• Must be comfortable working in a highly innovative, changing, fast-paced environment and able to multi-task.
• Ability to work under pressure and meet tight deadlines. Has the discipline to stay focused and complete specific tasks.
• Detail oriented with good organizational skills. Team player with excellent verbal and written communication skills.

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future. ​

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​

• This job is eligible to participate in our short-term incentive programs. ​

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of  any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. ​

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled. 

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

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