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Grafton Sciences

Chief of Staff

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In-Office
Redwood City, CA
In-Office
Redwood City, CA

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About Grafton Sciences

We’re building AI systems with general physical ability, the capacity to experiment, engineer, or manufacture anything. We believe achieving this is a key step toward building superintelligence. With deep technical roots and real-world progress at scale (for example, a $42 million NIH program), we’re pushing the frontier of physical AI. Joining us means inventing from first principles, owning real systems end to end, and helping build a capability the world has never had before.

About The Role

We’re looking for a Chief of Staff who operates as an extension of the CEO—someone who removes obstacles, drives clarity, and ensures the company is moving fast. This is a high-leverage, high-trust role for an individual with strong technical intuition, exceptional execution ability and a founder-type mindset.

Responsibilities

  • Serve as the CEO’s right hand, taking on anything that blocks the company, with enough technical depth to meaningfully operate in a deep-tech environment.

  • Own whatever is bottlenecking you that day: research, modeling, recruiting support, vendors, docs, process, investor prep

  • Run cross-functional projects that cut across hardware, software, operations, and fundraising

  • Take rough requests from you and turn them into structured plans, then execute

  • Build and maintain internal coordination systems so the company “runs like a machine”

Qualifications

  • Very high throughput, biased to action

  • Technical background preferred, Ideally in the fields of CS, physics, biology, chemistry, or synthesis

  • Founder-type mindset: willing to do anything, not precious about scope

  • Comfortable in chaos and incomplete information

  • Learns new domains quickly (finance, legal, ops, whatever is needed)

Above all, we look for candidates who can demonstrate world-class excellence

HQ

Grafton Sciences Redwood, California, USA Office

Redwood, CA, United States

Grafton Sciences San Francisco, California, USA Office

San Francisco, CA, United States

What you need to know about the San Francisco Tech Scene

San Francisco and the surrounding Bay Area attracts more startup funding than any other region in the world. Home to Stanford University and UC Berkeley, leading VC firms and several of the world’s most valuable companies, the Bay Area is the place to go for anyone looking to make it big in the tech industry. That said, San Francisco has a lot to offer beyond technology thanks to a thriving art and music scene, excellent food and a short drive to several of the country’s most beautiful recreational areas.

Key Facts About San Francisco Tech

  • Number of Tech Workers: 365,500; 13.9% of overall workforce (2024 CompTIA survey)
  • Major Tech Employers: Google, Apple, Salesforce, Meta
  • Key Industries: Artificial intelligence, cloud computing, fintech, consumer technology, software
  • Funding Landscape: $50.5 billion in venture capital funding in 2024 (Pitchbook)
  • Notable Investors: Sequoia Capital, Andreessen Horowitz, Bessemer Venture Partners, Greylock Partners, Khosla Ventures, Kleiner Perkins
  • Research Centers and Universities: Stanford University; University of California, Berkeley; University of San Francisco; Santa Clara University; Ames Research Center; Center for AI Safety; California Institute for Regenerative Medicine

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