The Principal Enterprise Data Architect will design and operationalize a data platform, integrating various systems while leading data governance and AI readiness efforts.
Cellares is building a next-generation Integrated Digital Manufacturing Operations (IDMO) platform to enable scalable, GMP-compliant cell therapy manufacturing. As part of this transformation, we are establishing a modern enterprise data foundation powered by Databricks to unify data across engineering, manufacturing, quality, supply chain, finance and commercial systems.
We are seeking a Principal Enterprise Data Architect, a highly hands-on individual contributor who will design, build, and operationalize our enterprise data platform from the ground up.
This is a multidisciplinary role and this individual will play a critical role in enabling real-time decision-making, data governance, and AI readiness across the enterprise. This role is a startup-style builder (90% hands-on) and will evolve into a foundational leader for scaling data capabilities, including alignment with our Global Capability Center (GCC).
Candidates should enjoy working in a fast-paced, mission-driven environment, and be prepared to tackle a broad selection of challenges as the company grows.
Responsibilities
- Architect and implement Databricks Lakehouse architecture
- Build end-to-end ETL/ELT pipelines
- Define canonical data models and scalable patterns
- Integrate SAP S/4HANA, Tulip MES, LabVantage LIMS, Salesforce, and engineering systems
- Align with API-first/event-driven architecture (MuleSoft / Workato)
- Define data glossary, lineage, and quality frameworks
- Implement Unity Catalog and governance aligned to GMP/21 CFR Part 11
- Prepare datasets for analytics and AI/ML use cases
- Support structured and unstructured data processing
- Evaluate and implement BI tools (Sigma, Looker, Tableau)
- Enable self-service analytics with governance
- Build pipelines using Python, SQL, Spark
- Establish reusable frameworks
- Partner with engineering, manufacturing, quality, finance and software teams
- Translate business needs into data solutions
Requirements
- Bachelor’s or Master’s degree in Engineering, Life Sciences, Information Systems, or related field
- 10+ years in data architecture/data engineering
- Strong Databricks/Spark experience
- Experience building data platforms from scratch
- Integration with ERP/MES/LIMS/CRM systems
- Azure cloud experience
- Self-awareness, integrity, authenticity, and a growth/entrepreneurial mindset
This is Cellares
Cellares is the first Integrated Development and Manufacturing Organization (IDMO) and takes an Industry 4.0 approach to mass manufacturing the living drugs of the 21st century. The company is both developing and operating integrated technologies for cell therapy manufacturing to accelerate access to life-saving cell therapies. The company’s Cell Shuttle integrates all the technologies required for the entire manufacturing process in a flexible and high-throughput platform that delivers true walk-away, end-to-end automation. Cell Shuttles will be deployed in Cellares’ Smart Factories around the world to meet total patient demand for cell therapies at global scale. Partnering with Cellares enables academics, biotechs, and pharma companies to accelerate drug development and scale out manufacturing, lower process failure rates, lower manufacturing costs, and meet global patient demand.
The company is headquartered in South San Francisco, California with its commercial-scale IDMO Smart Factory in Bridgewater, New Jersey. The company is backed by world-class investors and has raised over $355 million in financing.
Leveling will be based on overall experience, education, and demonstration of knowledge throughout the interview process.
Cellares South San Francisco, California, USA Office
345 Allerton Ave, South San Francisco, CA, United States, 94080
Similar Jobs
Digital Media • Kids + Family • Music • News + Entertainment
Lead end-to-end data architecture and cloud modernization on GCP and Oracle, design scalable ETL/ELT and streaming pipelines, implement ERP integrations (SAP/Oracle/Coupa/Anaplan), apply data mesh and governance, enable AI/ML analytics, and provide technical leadership and mentorship.
Top Skills:
AnaplanApache AirflowApi IntegrationsBigQueryCa SchedulerCloud FunctionsCloud Storage (Gcs)ComposerCoupaData MeshEtl/EltGoogle Cloud PlatformOracleOracle ErpPub/SubPythonSAPSQL
Blockchain • Fintech • Payments • Financial Services • Cryptocurrency • Web3
Lead detection and response efforts: build detections, manage SIEM and orchestration tooling, deploy AI in SOC workflows, investigate incidents across AWS/EKS environments, support threat modeling and vulnerability scanning, and take on-call shifts.
Top Skills:
Ai ToolingAWSBlockchainEksGoGoogle SuiteKubernetesmacOSOrchestration PlatformsPythonSIEMSlack
3 Hours Ago
Aerospace • Information Technology • Software • Cybersecurity • Design • Defense • Manufacturing
Provide technical support and troubleshooting for aircraft Environmental Control Systems across Boeing models. Liaise with customers and cross-functional teams, develop and document engineering dispositions, perform tests and root cause analysis, and create technical documentation to return airplanes to service and resolve in-service system issues.
Top Skills:
Airflow AnalysisAirflow ModelingAnti-Ice ProtectionBoeing 737MaxBoeing 737NgBoeing 777Boeing 777XBoeing 787Cabin Air ConditioningCabin PressurizationCargo Smoke DetectionEnvironmental Control SystemsFire Suppression SystemsFuel Tank InertingInstrument CoolingNitrogen Generation SystemPneumatic SystemsTemperature Control SystemThermodynamics
What you need to know about the San Francisco Tech Scene
San Francisco and the surrounding Bay Area attracts more startup funding than any other region in the world. Home to Stanford University and UC Berkeley, leading VC firms and several of the world’s most valuable companies, the Bay Area is the place to go for anyone looking to make it big in the tech industry. That said, San Francisco has a lot to offer beyond technology thanks to a thriving art and music scene, excellent food and a short drive to several of the country’s most beautiful recreational areas.
Key Facts About San Francisco Tech
- Number of Tech Workers: 365,500; 13.9% of overall workforce (2024 CompTIA survey)
- Major Tech Employers: Google, Apple, Salesforce, Meta
- Key Industries: Artificial intelligence, cloud computing, fintech, consumer technology, software
- Funding Landscape: $50.5 billion in venture capital funding in 2024 (Pitchbook)
- Notable Investors: Sequoia Capital, Andreessen Horowitz, Bessemer Venture Partners, Greylock Partners, Khosla Ventures, Kleiner Perkins
- Research Centers and Universities: Stanford University; University of California, Berkeley; University of San Francisco; Santa Clara University; Ames Research Center; Center for AI Safety; California Institute for Regenerative Medicine
