Principal Scientist, Oncology Research

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.
 

Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact.
 

We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together.
Job Description
 

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.

Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact.

We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together.
 

Position Overview:

We are seeking a highly motivated and creative Principal Scientist to support Gilead’s growing Oncology targeted large molecule portfolio. The successful candidate will be an integral senior member of a high performing research team dedicated to (i) identifying and validating novel targets for T cell Engagers, (ii) developing next-generation approaches to make T cell engagers safer and more efficacious against solid tumors through engineering or novel combination approaches, and (iii) deepen our understanding of the mechanism of action of T cell engagers and resistance mechanisms through innovative pre-clinical model development and analysis. In this role, the candidate will manage an internal research team and interact in a highly cross-functional manner across multiple departments to ideate and advance projects. In addition, the candidate will use his or her extensive knowledge of the T cell Engager and related fields to supervise and guide multiple programs and support external diligence efforts and evaluate assets as well as novel platforms.
 

Specific Responsibilities: 

• Design and lead cross-functional therapeutic projects in the field of T cell engagers and enhancers of T cell functions, leveraging internal and external resources.

• Role is expected to lead from the bench and actively participate in the design and execution of critical experiments

• Support the development of Oncology portfolio at Gilead through project ideation and scientific experimentation.

• Manage reports and lead a productive research team dedicated to identifying and validating new targets for given cancer indications and developing new biologics platforms for optimal engagement and stimulation of T cells.

• Significantly contribute to the evaluation of external asset and platform opportunities

• Contribute to the preparation of scientific reports, manuscripts, and patent applications.

Minimum Qualifications:

• Bachelor's Degree and 10 years experience

OR

• Master's Degree and 8 years experience

OR

• PhD/PharmD and 2 years experience

OR

• MD

Preferred Qualifications:

• Ph.D. in Immunology, Oncology, Cell Biology or related field.

• 5+ years of relevant experience with PhD; 6+ Years relevant industry experience and with postdoctoral training preferred

• Minimum 3 years in a managerial role with demonstrated team management experience.

• Proven track record of publications and/or patents

• Exceptional problem-solving abilities and scientific judgment

• Deep expertise and understanding of Oncology and immune-oncology and the competitive landscape.

• Demonstrated ability to design and execute in vitro and in vivo studies for Oncology and immuno-oncology.

• Proficiency in data analysis tools and statistical software; experience with AI/ML applications is a plus

• Strong project management skills with ability to oversee multiple projects simultaneously while maintaining high quality standards.

• Excellent verbal and written communication skills with the ability to influence and collaborate effectively across disciplines and present to executive leadership.

 

The salary range for this position is: $195,670.00 - $253,220.00. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*.

For additional benefits information, visit:

https://www.gilead.com/careers/compensation-benefits-and-wellbeing

* Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.

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