Research Associate I- Conklin Lab

The Gladstone Institutes is a leading independent, not-for-profit research organization dedicated to improving human health through groundbreaking biomedical research and education. Our work spans neuroscience, cardiovascular biology, immunology, and stem cell biology, with a strong emphasis on understanding and treating disease. With approximately 600 team members, including world-renowned scientists and biomedical leaders, Gladstone fosters a collaborative and innovative environment. Located at the Mission Bay Campus in a state-of-the-art facility, we offer competitive salaries, comprehensive benefits, and the resources to empower individuals to maximize their potential and make a meaningful impact on global health.

About the role:

The Conklin Laboratory at the Gladstone Institutes is seeking a motivated and detail-oriented Research Associate to join our team. Our research focuses on human therapeutic genome editing in close collaboration with the Innovative Genomics Institute (IGI). We study the fundamental mechanisms of DNA repair and DNA excision, using human motor neurons as a model system.

This position offers a unique opportunity to contribute to cutting-edge work at the intersection of genome engineering, molecular biology, and neurobiology. The role is particularly well-suited for recent graduates seeking to gain advanced research experience before pursuing graduate or medical school.

What you will do:

• Conduct molecular and cell biology experiments related to genome editing and DNA repair

• Perform mammalian cell culture (human and animal), including maintenance and differentiation of motor neurons

• Assist in assay development, data collection, and quantitative analysis

• Process animal tissue samples (e.g. DNA/RNA isolation, tissue staining) (no live animal handling will be required in this role)

• Collaborate closely with team members and external collaborators

• Maintain detailed and organized experimental records

• Contribute to lab meetings and presentations of research findings

• Support general laboratory operations, including reagent preparation and equipment maintenance

What you will need:

• Bachelor’s degree (B.A. or B.S.) in Biology, Molecular Biology, Genetics, Biochemistry, or a related field preferred

• 9+ months of laboratory research experience

• Strong foundation in molecular biology techniques (e.g., PCR, cloning, Western blotting)

• Experience with mammalian cell culture preferred

• Excellent organizational, analytical, and communication skills

• Ability to work both independently and collaboratively in a dynamic research environment

What to include with your application:

• A brief description of research interests, relevant experience, and career goals with 2 professional references

• A current CV or resume