Research Associate II/Senior Research Associate I, Biologics

Key Responsibilities:

• Conduct protein characterization using SDS-PAGE, HPLC, LC/MS, DLS, and other biophysical/analytical methods. 
• Generate bispecific antibodies through controlled Fab-arm exchange (cFAE).
• Execute secondary protein purification (IEX, SEC, HIC) when necessary. 
• Biotinylation and fluorescent dye conjugation of antibodies and proteins. 
• Conducts biolayer interferometry (BLI) assays to evaluate antibody-protein interactions. 
• Prepare solutions for binding assessments and in vivo studies through formulation and concentration adjustment. 
• Update and maintain protein inventories as well as accurate and timely documentation of experimental work in electronic laboratory notebooks (ELNs).
• Contribute to troubleshooting processes, data analysis, and interpretation.
• Opportunity to represent functional area through presentation of data during research team meetings or broader company-wide meetings  
• Conducts routine maintenance, calibration, and troubleshooting of laboratory instruments as needed. 

Requirements:

• BS in Biology, Biochemistry, or related field with at least 2+ years of relevant experience OR MS with 0+ years of relevant experience. Previous industry experience is strongly preferred.
• Proficiency with FPLC systems (e.g., AKTA) and associated software (e.g., Unicorn).
• Experience in characterizing recombinant proteins, particularly monoclonal/bispecific antibodies, and associated analytical techniques (SDS-PAGE, HPLC, LC/MS, DLS, BLI).
• Basic understanding of protein conjugation technologies (NHS chemistry, enzymatic conjugation, fluorescent dye labeling) and related QC is a plus.
• Demonstrates strong organizational skills and meticulous attention to detail to manage experimental workflows, while effectively communicating findings across multidisciplinary teams.
• Ability to work both independently and collaboratively in a team-oriented research environment.