Scientific Director, ADC Chemistry

Position Overview
The Scientific Director of ADC Chemistry will be a key scientific innovator and operational leader responsible for shaping and advancing the ADC Discovery portfolio. This role requires a creative and scientifically driven leader who can identify and originate new research opportunities, guide early-stage discovery projects, and contribute to the development of our ADC Discovery strategy across the research organization. The successful candidate will manage a team of chemists, lead multidisciplinary project teams, and implement operational improvements that enable rapid exploration and execution of innovative ideas aligned with our organizational strategy and goals.
Key Responsibilities

• Help deliver the next generation of ADC therapeutics. Promote a culture of innovation by integrating new ideas, targets, technologies and methodologies into the ADC Discovery organization.
• Provide leadership to multidisciplinary project teams focused on development of the next generation of ADCs. Leverage a collaborative mindset to oversee strategic project planning, operational execution across internal teams and partner lines, and clear communication of project achievements and risks.
• Manage a team of ADC chemists, fostering a collaborative and high-performing work environment. Provide supportive coaching, professional development, and performance feedback to direct reports to increase employee engagement and impact.
• Support operational improvements within ADC Chemistry and across the ADC Discovery organization. Proactively identify opportunities to increase productivity and quality through optimization of workflows and introduction of best practices.
• Contribute to the strategic direction of the ADC Discovery organization and align ADC Chemistry initiatives with broader organizational goals.

Qualifications

• Ph.D. in Chemistry, Biochemistry, or a related scientific discipline, with 12+ years of experience in the pharmaceutical or biotechnology industry.
• Prior experience in ADC discovery with a focus on novel payload development is preferred. Candidates with extensive experience in small molecule modalities and interest in targeted drug delivery will also be considered.
• Demonstrated success in advancing innovative scientific projects and driving operational improvements.
• Ability to lead and develop high-performing teams in a matrixed organization.
• Proven ability to manage direct reports for individual performance and career growth.
• Strong communication, interpersonal, and organizational skills.

Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
Additional Information:

• Relocation support available
• Work Location Assignment: On Premise
• Last Day to Apply: March 20, 2026

The annual base salary for this position ranges from $162,900.00 to $271,500.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
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EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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Research and Development