Scientist, Analytical Development (Contract)

About Allogene:

Allogene Therapeutics, with headquarters in South San Francisco, is a clinical-stage biotechnology company pioneering the development of allogeneic chimeric antigen receptor T cell (AlloCAR T) products for cancer and autoimmune disease. Led by a management team with significant experience in cell therapy, Allogene is developing a pipeline of “off-the-shelf” CAR T cell product candidates with the goal of delivering readily available cell therapy on-demand, more reliably, and at greater scale to more patients.

About the role:

Allogene’s Process and Product Development organization is building a world class team that is focused on delivering potentially lifesaving therapies to patients. We are seeking a highly motivated individual to join us as a Scientist, Analytical Development in a contract capacity. This role will be a hands-on role reporting to the Associate Director, Attribute Science and PPD. The position is a lab-based, onsite role based at Allogene’s headquarters in South San Francisco. This is a 1-year contract opportunity with the possibility of extension or contract-to-hire.

Responsibilities include, but are not limited to:

• Participate in method execution and qualification in support of analytical method development & performance, drug product characterization and product release
• Primarily optimize and help qualify analytical test methods involving qPCR, ddPCR and other molecular biology assays, as well as support the development of cell-based and/or immunoassays
• Actively contribute to the execution of NGS-based pipelines for the characterization of CAR T manufacturing processes and products
• Work with CROs to identify and implement process improvements focused on quality, turnaround time, and cost
• Document laboratory procedures and experimental data in ELN with great attention to detail
• Maintain, calibrate, and operate analytical instruments
• Work with a cross-functional team to advance the development of Allogene’s CAR T programs
• Other duties as assigned

Position Requirements & Experience:

• Self-motivated, detail-orientated, and eager to be part of a positive work environment with other researchers to develop allogeneic CAR T cell therapies targeting cancer
• Bachelor’s or Master’s degree with at least 3 years of relevant cell biology, immunology or biochemistry experience
• Cell culture techniques, cell banking and cell bases assay development experience
• At least 2 years of hands-on experience with nucleic acid isolations, quantification, and NGS assay workflows (bulk RNA-seq, single-cell omics, WGS, etc.)
• Specific experience with quantitative analytical techniques including qPCR, ddPCR, ELISA and fluorescence-based enzymatic assays
• Experience with cell therapy products is a plus
• Working knowledge of Quality control and GMP requirements, and BLA enabling activities is a plus
• Excellent organizational skills and an ability to prioritize effectively to deliver results within established timelines
• Ability to work independently and as part of a team, strong interpersonal skills including relationship building, conflict resolution, and verbal and written communication are essential in this collaborative work environment
• Candidates must be authorized to work in the U.S.

We offer a chance to work with talented people in a collaborative environment. Actual pay will be determined based on experience, qualifications, geographic location, business needs, and other job-related factors permitted by law.

As an equal opportunity employer, Allogene is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job-related characteristics or other prohibited grounds specified in applicable federal, state and local laws. We also embrace differences in experience and background, and welcome diversity of opinions and thought with active recruitment and internships designed to create a stronger and better Allogene that is focused on developing life-changing products for patients. #LI-Onsite #LI-TF1