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Who We Are & What We Do
At Helix, our mission is simple: to help everyone improve their lives through their DNA.
Ready to make a real-world impact with your skills? At Helix, we're transforming healthcare by making genomics a standard of care. We partner with health systems and life science companies to accelerate the integration of genomic data into clinical practice. Join us in building a future where healthcare is personalized, proactive, and powered by genomics.
As a Senior Data Scientist, you will:
- Analyze data to identify patterns and trends toward improving health and/or financial outcomes, e.g., disease prevalence, risk factors, treatment opportunities, and the effectiveness of health interventions
- Develop a portfolio of reports and data insights that communicates the value and opportunity of Helix population health, diagnostic, and research data for life science companies
- Develop reusable dashboards, analytical reports, datasets, and analytic integrations, by working with medical affairs, research, product, data science, and commercial teams where required
- Evaluate market opportunities by creating and maintaining therapeutic area and service line-specific data models
- Leverage real-world patient data spanning engagement, medical history, outcomes, social determinants, and genetics, partner with life sciences to provide focused and effective data-driven narratives
- Collaborate across multiple teams including analytics, data engineering, medical affairs, clinical, research, business development, strategy, and product
About you:
- Master’s Degree or higher in Data Science, Biostatistics, Medical Informatics, Epidemiology, Public Health, or other related scientific discipline
- At least 3 years of experience working with US healthcare data in health care plan/services, public health, RWE, research, or a related field
- Direct experience using LLMs or agentic tools (Claude Code, Cline, Copilot, etc) in a research or clinical data workflow
- Strong healthcare data experience with electronic health records and/or claims data
- Experience with common clinical coding standards (ex: ICD, CPT, LOINC, SNOMED-CT)
- Understanding of genetic data and knowledge of variant annotation tools and databases
- Strong programming skills in Data Analysis and Visualization, SQL, Python, Databases
- Strong analytical and problem-solving skills along with business acumen; desire to learn and grow in healthcare industry
- Worked with real world data and have a strong understanding of analytics and how it is leveraged within the life sciences industry
- Entrepreneurial spirit and willingness to jump into new areas
- Knowledge of population health metrics
- Excellent communication and storytelling skills with a variety of cross-functional stakeholders
Pluses:
- Experience working with the OMOP CDM
- Experience working with large-scale genomic data
- Experience using Airflow, Nextflow, or other workflow orchestration
- Experience working in cloud environments
- Experience analyzing RWE data at or with life sciences customers
Expected Interview Process:
1) Manager Screen 2) Recruiter Screen 3) Technical Interview 4) Final Loop 5) Offer
Expected Pay For This Role:
There are 3 distinct parts to your Helix offer: 1) Base Salary 2) Annual Bonus 3) Equity
- Expected Helix Base: $139,000 - $186,250
- Expected Helix Discretionary Annual Bonus: 10% of your annual salary
- Equity: We offer generous equity at Helix. If you receive a Helix offer your recruiter will book dedicated time with you to educate you on our equity model.
Aside from working alongside brilliant, dedicated, passionate, down-to-earth, curious, warm, and thoughtful people, we also provide great benefits:
- Comprehensive Health Insurance with Date of Hire eligibility
- Above average employer paid premium coverage
- 12 weeks Helix Paid Parental Leave option
- 401(k) with employer matching of up to 3% and 100% Vesting on the Date of Hire
- Comprehensive Well-Being Benefits
- Flexible PTO
- Remote options for many roles and a home office stipend
What To Expect During Your First 90 days:
- First 30 days: you’ll spend time learning the Helix way, completing training and onboarding for your roles, and getting introduced to your team and relevant stakeholders. You’ll also gain a deeper understanding of our customers, our products, the impact we make in the lives of our communities, and how to thrive at Helix through participation in Helix U.
- Day 30 - 60: you’ll spend time contributing to projects, deeply familiarizing yourself with team and company processes, and developing a deeper understanding of Helix’s products, services and capabilities.
- Day 60 - 90: you’ll build your OKRs with your manager, start to take ownership of projects and initiatives on your team, and begin to demonstrate your impact on the Helix mission.
Helix is proud to be an equal opportunity employer, and committed to providing employment opportunities regardless of race, religious creed, color, national origin, ancestry, physical disability, mental disability, medical condition, genetic information, marital status, sex, gender, gender identity, gender expression, pregnancy, childbirth and breastfeeding, age, sexual orientation, military or veteran status, or any other protected classification, in accordance with applicable federal, state, and local laws.
#LI-Remote
CompensationThe base pay range for this role is $139,000 – $186,250 per year.
Helix San Mateo, California, USA Office
101 S Ellsworth Ave #350, San Mateo, CA, United States, 94401
What you need to know about the San Francisco Tech Scene
San Francisco and the surrounding Bay Area attracts more startup funding than any other region in the world. Home to Stanford University and UC Berkeley, leading VC firms and several of the world’s most valuable companies, the Bay Area is the place to go for anyone looking to make it big in the tech industry. That said, San Francisco has a lot to offer beyond technology thanks to a thriving art and music scene, excellent food and a short drive to several of the country’s most beautiful recreational areas.
Key Facts About San Francisco Tech
- Number of Tech Workers: 365,500; 13.9% of overall workforce (2024 CompTIA survey)
- Major Tech Employers: Google, Apple, Salesforce, Meta
- Key Industries: Artificial intelligence, cloud computing, fintech, consumer technology, software
- Funding Landscape: $50.5 billion in venture capital funding in 2024 (Pitchbook)
- Notable Investors: Sequoia Capital, Andreessen Horowitz, Bessemer Venture Partners, Greylock Partners, Khosla Ventures, Kleiner Perkins
- Research Centers and Universities: Stanford University; University of California, Berkeley; University of San Francisco; Santa Clara University; Ames Research Center; Center for AI Safety; California Institute for Regenerative Medicine
