Senior Manager, Commercial Supply Chain Systems & Labeling

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers.  The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

We are seeking a cross-functional Senior Manager to lead commercial labeling, serialization, and supply chain systems readiness in support of global product launches. This role sits at the intersection of Supply Chain, Regulatory, Quality, CMC, and IT, and is responsible for implementing and maintaining processes and systems that ensure compliant execution of labeling, traceability, and product data. The ideal candidate brings hands-on expertise in global labeling execution, serialization, and master data governance, along with strong operational acumen and experience coordinating across internal and external stakeholders.

Key Responsibilities:

Labeling & Artwork Operations

• Lead commercial labeling operations, including creation, proofing, approval, and implementation of global labels and packaging artwork.

• Partner with Regulatory Affairs, Quality, CMC, and Commercial teams to align on content, timing, and execution across new product introductions and lifecycle changes.

• Manage external artwork vendors and contract packaging partners to ensure accurate and timely delivery of compliant labeling components.

Serialization & Traceability

• Serve as the business process owner for serialization systems, including DSCSA and EU FMD compliance, EPCIS event management, and data exchange.

• Coordinate with CMOs, CMC teams, and 3PL partners to ensure traceability and security features are correctly implemented across all packaging levels.

• Collaborate with IT and system vendors to support serialized product onboarding and regulatory reporting readiness.

 Master Data Governance & Systems Integration

• Oversee and execute master data governance across product, packaging, and labeling systems (e.g., BoMs, GTINs, material masters).

• Own business processes for packaging configuration and labeling setup, ensuring high data quality and change control compliance.

• Lead system readiness and UAT activities for tools that support serialization, labeling, and packaging data flow.

• Act as a liaison to IT and business process owners to maintain alignment between master data, ERP, and regulatory systems.

Cross-Functional Coordination

• Serve as a central point of coordination between Supply Chain, CMC, Regulatory, Quality, and external partners to ensure seamless implementation of labeling and serialization activities.

• Support inspection readiness and ensure documentation and systems are compliant with health authority expectations.

Required Skills, Experience and Education:

• Bachelor’s degree in Life Sciences, Engineering, Supply Chain, or a related field.

• 8+ years of experience in biopharma, including 5+ years in labeling, packaging, serialization, or master data systems.

• In-depth understanding of global labeling regulations and serialization frameworks (DSCSA, EU FMD).

• Strong knowledge of product and packaging master data, including governance principles and integration with ERP/serialization systems.

• Experience working with CMOs, 3PLs, and external artwork or serialization vendors.

• Familiarity with serialization platforms (e.g., TraceLink), ERP systems (e.g., SAP), and digital artwork tools.

• Proven ability to lead cross-functional projects in a regulated, fast-paced commercial environment.

Preferred Skills:

• Experience in the biopharmaceutical or life sciences industry, particularly in commercial supply chain, packaging, or regulatory support functions.

• Familiarity with ERP and serialization systems (e.g., SAP, TraceLink, SAP ATTP, Oracle).

• Exposure to master data governance, packaging configuration, and regulatory change control processes.

• Experience supporting product launches, labeling changes, or post-approval regulatory updates.

• Strong collaboration skills and experience working cross-functionally with Regulatory, CMC, Quality, IT, and external partners (e.g., CMOs, 3PLs, design vendors).

• Strong organizational and communication skills, with the ability to manage timelines and deliverables in a fast-paced, dynamic environment.

• Interest in working within a science-driven, compliance-focused setting. #LI-Hybrid   #LI-CT1