Lead and support IT/OT operations in a biotech manufacturing lab, ensuring system reliability and compliance with industry regulations.
We are seeking a hands-on Senior Operational Technology Engineer to lead and support IT/OT operations in a global cell therapy manufacturing lab environment.
This role is responsible for end-to-end OT infrastructure, including network and security on proprietary equipment, while ensuring secure access management, compliant change control, and 24x7 operations. The ideal candidate will combine deep technical expertise with strong leadership to drive system reliability, scalability, and regulatory compliance across multiple sites.
Candidates should enjoy working in a fast-paced, mission-driven environment, and be prepared to tackle a broad selection of challenges as the company grows.
Responsibilities
- Manage and deliver OT systems and technology for the company’s industrial and cell manufacturing environments
- Own and maintain a robust OT roadmap, including project objectives, prioritization, and implementation plans
- Ensure OT production environments adhere to security best practices and comply with relevant regulations
- Provide hands-on technical support and troubleshooting for production-related OT/IT issues, ensuring minimal disruption to 24x7 operations
- Implement and monitor OT production systems to guarantee 24x7 uptime and reliability, including network, server, biotech manufacturing lab, and proprietary equipment
- Develop and deliver training programs for new OT staff relating to production environment
- Contribute to creating, maintaining SOPs, Policies, and Process
- Lead and support GMP-related activities, including change control, system validation, qualification (IQ/OQ/PQ), and audit readiness
- Own OT access management processes, including user provisioning, role-based access control, and periodic access reviews to ensure compliance with GxP, data integrity, and cybersecurity requirements
- Ensure compliance with industry regulations, standards, and best practices related to OT and data security
- Provide backup support to Corporate IT as needed to ensure continuity of enterprise IT services
Requirements
- Bachelor's Degree in related field or proper training
- 7+ years of relevant experience
- Proven experience in IT management with a manufacturing or industrial setting, with a strong focus on 24x7 operational support
- Experience with monitoring, server management, and cybersecurity best practices
- Experience with Fortigate firewalls, Hirschmann industrial switches, lab and warehouse equipment
- Experience with various applications such as Nutanix Prism, SharePoint, and JIRA
- Experience working in a biotech regulated environment
- Knowledge of and experience with current Good Manufacturing Practices (cGMP) required
- Ability to independently prioritize work and deliver results effectively in a fast-paced environment.
- Ability to be a strong problem-solving skills and the ability to work under pressure
- Requires availability for on-call support and extended hours during critical system issues to maintain 24x7 operations
- Self-awareness, integrity, authenticity, and a growth/entrepreneurial mindset
This is Cellares
Cellares is the first Integrated Development and Manufacturing Organization (IDMO) and takes an Industry 4.0 approach to mass manufacturing the living drugs of the 21st century. The company is both developing and operating integrated technologies for cell therapy manufacturing to accelerate access to life-saving cell therapies. The company’s Cell Shuttle integrates all the technologies required for the entire manufacturing process in a flexible and high-throughput platform that delivers true walk-away, end-to-end automation. Cell Shuttles will be deployed in Cellares’ Smart Factories around the world to meet total patient demand for cell therapies at global scale. Partnering with Cellares enables academics, biotechs, and pharma companies to accelerate drug development and scale out manufacturing, lower process failure rates, lower manufacturing costs, and meet global patient demand.
The company is headquartered in South San Francisco, California with its commercial-scale IDMO Smart Factory in Bridgewater, New Jersey. The company is backed by world-class investors and has raised over $355 million in financing.
Leveling will be based on overall experience, education, and demonstration of knowledge throughout the interview process.
Cellares South San Francisco, California, USA Office
345 Allerton Ave, South San Francisco, CA, United States, 94080
Similar Jobs
AdTech • Digital Media • Marketing Tech
The Principal Technical Program Manager leads the strategic planning and execution of complex technical programs, aligning them with business goals and managing cross-functional teams.
Top Skills:
Advertising Technologies
Cloud • Information Technology • Productivity • Security • Software • App development • Automation
Develop actionable go-to-market strategies for AI sales and consumption pricing while driving business growth and engagement. Collaborate cross-functionally to influence strategic direction and optimize customer experience.
Top Skills:
AIData VisualizationFinancial AnalysisSaaS
Artificial Intelligence • Automotive • Greentech • Information Technology • Machine Learning • Software • Cybersecurity
The SEO Specialist II enhances clients' online presence through data analysis, local SEO tactics, strategic content implementation, and collaboration with internal teams. They provide performance reports, client support, and ongoing SEO education while managing SEO-related requests and trends.
Top Skills:
CopyscapeDba PlatformGoogle AnalyticsGoogle Search ConsoleLocal FalconMajestic SeoMoz ProSem Rush
What you need to know about the San Francisco Tech Scene
San Francisco and the surrounding Bay Area attracts more startup funding than any other region in the world. Home to Stanford University and UC Berkeley, leading VC firms and several of the world’s most valuable companies, the Bay Area is the place to go for anyone looking to make it big in the tech industry. That said, San Francisco has a lot to offer beyond technology thanks to a thriving art and music scene, excellent food and a short drive to several of the country’s most beautiful recreational areas.
Key Facts About San Francisco Tech
- Number of Tech Workers: 365,500; 13.9% of overall workforce (2024 CompTIA survey)
- Major Tech Employers: Google, Apple, Salesforce, Meta
- Key Industries: Artificial intelligence, cloud computing, fintech, consumer technology, software
- Funding Landscape: $50.5 billion in venture capital funding in 2024 (Pitchbook)
- Notable Investors: Sequoia Capital, Andreessen Horowitz, Bessemer Venture Partners, Greylock Partners, Khosla Ventures, Kleiner Perkins
- Research Centers and Universities: Stanford University; University of California, Berkeley; University of San Francisco; Santa Clara University; Ames Research Center; Center for AI Safety; California Institute for Regenerative Medicine
