Spyre Therapeutics Logo

Spyre Therapeutics

Senior Payroll and Accounting Specialist

Posted 15 Days Ago
Remote
Hiring Remotely in US
110K-130K Annually
Senior level
Remote
Hiring Remotely in US
110K-130K Annually
Senior level
The Senior Payroll and Accounting Specialist will manage payroll and accounting processes, ensuring compliance and accuracy in financial reporting, tax management, and equity administration while optimizing workflows in a growing biotech company.
The summary above was generated by AI

Spyre Therapeutics is a clinical-stage biotechnology company committed to developing next-generation therapies that elevate the standard in immunology by delivering more complete disease control, greater durability, and a simpler treatment experience for patients. Spyre's pipeline includes investigational extended half-life antibodies targeting α4β7, TL1A, and IL-23.

Role Summary:

Spyre Therapeutics, Inc., is actively recruiting an experienced Senior Payroll and Accounting Specialist to join our accounting team. The Payroll and Accounting Specialist will be a key member of the accounting department, responsible for the integrity of the Company’s compensation cycles and equity administration. Responsibilities include full-cycle general ledger accounting, end-to-end payroll administration, equity platform management, and ensuring strict adherence to Sarbanes-Oxley (SOX) requirements. This position will support our increased operational needs as our company grows, playing a vital role in reconciling stock-based compensation, managing payroll tax compliance, and other accounting tasks as needed. Attention to detail and the ability to maintain precise account balances and general ledger accuracy are all essential skills for this position. The ideal candidate should be comfortable working collaboratively with cross-functional teams and independently and excel when faced with the unique challenges of a scaling organization.

Key Responsibilities:

  • Manage the full-cycle payroll process, including data entry, tax withholdings, and benefits deductions, etc.
  • Ensure all payroll activities align with federal, state, and local tax regulations, including the proper handling of withholdings and filings.
  • Perform regular audits of payroll data and reconcile payroll bank accounts to ensure accuracy and identify discrepancies.
  • Coordinate with HR to ensure accurate deductions for health insurance, retirement plans (401k), and other voluntary benefits.
  • Act as the primary point of contact for staff regarding pay-related inquiries, resolving issues related to paychecks or tax forms with high confidentiality.
  • Identify opportunities to streamline payroll workflows and improve the efficiency of the payroll software or HRIS.
  • Prepare and post monthly journal entries for payroll accruals, benefits, taxes, and other standard corporate expenses.
  • Maintain T&E system including syncing to the Company’s ERP and reviewing expense transactions for compliance with Company policies.
  • Assist in the preparation of monthly and quarterly financial statements by ensuring all payroll-related expenses are accurately categorized.
  • Maintain and document internal controls (such as SOX compliance procedures) to ensure the integrity of financial reporting and prevent fraud.
  • Facilitate the issuance of new equity awards (RSUs, Stock Options, or ESPP) by ensuring all grant agreements are properly executed and recorded in the equity platform.
  • Monitor vesting schedules and process stock option exercises, ensuring the accurate flow of data between the equity platform and payroll for tax withholding.
  • Other duties as assigned.

Ideal Candidate:

  • Bachelor’s degree in Accounting or related field
  • 5+ years of payroll and accounting experience
  • Experience managing payroll and tax withholdings across multiple states. Experience with international locations is a plus.
  • Proficiency in payroll/HRIS and equity management platforms (i.e. Rippling, Fidelity, E*TRADE)
  • Solid understanding of the lifecycle of various equity vehicles, including RSUs, NSOs, ISOs, and ESPPs.
  • A proven track record of handling highly sensitive executive compensation and employee financial data with total discretion.
  • Excellent organizational, analytical, prioritization and problem-solving skills in an environment of high volume of projects; detail-oriented
  • Possesses a professional demeanor, discretion and judgment
  • Ability to work effectively and establish and promote positive relationships
  • Self-starter who possesses initiative and ability to work alone while capable of driving business results without significant supervision
  • Must have schedule flexibility to meet the demands of monthly and quarterly close
  • Excellent verbal and written communication skills
  • Ability to work effectively with all employee levels and external contacts

What We Offer:

  • Opportunity to work in a fast-paced, dynamic environment where you help shape the culture of our young company, contribute broadly to advance meaningful medicines, and learn quickly.
  • Market competitive compensation and benefits package, including base salary, performance bonus, equity grant opportunities, health, welfare & retirement benefits.
  • Unlimited PTO
  • Two, one-week company-wide shutdowns each
  • Commitment to provide professional development opportunities.
  • Remote working environment with frequent in-person meetings to address complex problems and build relationships.

The expected salary range offer for this role is $110,000 to $130,000. Actual pay offered may vary depending on job related knowledge, experience, education, and geographic location. 

As an equal opportunity employer, Spyre is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job-related characteristics or other prohibited grounds specified in applicable federal, state and local laws. We also embrace differences in experience and background, and welcome diversity of opinions and thought with active recruitment designed to create a stronger and better Spyre that is focused on developing life-changing products for patients.

Spyre Therapeutics, along with other biotech companies, has become aware of a surge in email scams targeting prospective job candidates within our industry. Please be aware that official recruiters at Spyre Therapeutics only use email addresses with the domain “@spyre.com.” We want to also emphasize that we never request candidates to make any purchases or divulge sensitive personal information via email.

Please also be aware that all job postings will be listed on our website at spyre.com/careers/.

Spyre Therapeutics San Francisco, California, USA Office

San Francisco, California, United States

Similar Jobs

45 Minutes Ago
Remote or Hybrid
Senior level
Senior level
Artificial Intelligence • Cloud • HR Tech • Information Technology • Productivity • Software • Automation
Lead and coach regional sales leaders and direct reps to drive new business and revenue growth. Own territory and quota planning, forecasting, pipeline management, C-level engagement, partner collaboration, and cross-functional alignment. Recruit and develop talent, support field teams to close deals, and retain/expand customer accounts while executing strategic sales initiatives to meet quarterly and annual targets.
Top Skills: AICRMServicenow
45 Minutes Ago
Remote or Hybrid
148K-230K Annually
Expert/Leader
148K-230K Annually
Expert/Leader
Artificial Intelligence • Cloud • HR Tech • Information Technology • Productivity • Software • Automation
Lead technical architecture and platform strategy for ServiceNow implementations across federal customers. Advise executives and engineering teams on instance strategy, integrations, governance, cloud application design, and technical debt reduction. Scope engagements, support sales, contribute leading practices, mentor others, and ensure long-term platform health and adoption.
Top Skills: AIAPIsCloudIntegrationsServicenow
45 Minutes Ago
In-Office or Remote
118K-232K Annually
Senior level
118K-232K Annually
Senior level
Aerospace • Information Technology • Software • Cybersecurity • Design • Defense • Manufacturing
Develop, deploy, and maintain RTOS and Linux (Yocto) configurations and hypervisor (Xen/KVM) integrations for safety-critical systems. Lead technical design, testing, performance analysis, and verification activities. Provide subject-matter expertise, tooling/process improvements, and support software lifecycle from requirements through deployment.
Top Skills: Arinc 653BazelBootloadersBuildrootCC++ClangDevice DriversDockerGccGitGitlab CiKvmLinux KernelPodmanPosixPythonRtosRustXenYoctoYocto Linux

What you need to know about the San Francisco Tech Scene

San Francisco and the surrounding Bay Area attracts more startup funding than any other region in the world. Home to Stanford University and UC Berkeley, leading VC firms and several of the world’s most valuable companies, the Bay Area is the place to go for anyone looking to make it big in the tech industry. That said, San Francisco has a lot to offer beyond technology thanks to a thriving art and music scene, excellent food and a short drive to several of the country’s most beautiful recreational areas.

Key Facts About San Francisco Tech

  • Number of Tech Workers: 365,500; 13.9% of overall workforce (2024 CompTIA survey)
  • Major Tech Employers: Google, Apple, Salesforce, Meta
  • Key Industries: Artificial intelligence, cloud computing, fintech, consumer technology, software
  • Funding Landscape: $50.5 billion in venture capital funding in 2024 (Pitchbook)
  • Notable Investors: Sequoia Capital, Andreessen Horowitz, Bessemer Venture Partners, Greylock Partners, Khosla Ventures, Kleiner Perkins
  • Research Centers and Universities: Stanford University; University of California, Berkeley; University of San Francisco; Santa Clara University; Ames Research Center; Center for AI Safety; California Institute for Regenerative Medicine

Sign up now Access later

Create Free Account

Please log in or sign up to report this job.

Create Free Account