Senior Research Associate/Associate Scientist, Antibody Characterization

Location: Redwood City
Company Overview:
ImmunEdge is a biopharmaceutical company committed to developing novel therapeutics for patients with serious or life-threatening diseases. With a highly experienced team of experts in immunology and drug development, we are pioneering innovative approaches to target and modulate key molecular pathways that regulate the immune response.
At ImmunEdge, we are driven by a shared commitment to improving human health through innovative science. We are building a culture based on kindness, collaboration, and a deep passion for advancing science. As an early joiner to the company, you will help cultivate an environment where every team member is encouraged to challenge ideas, think critically, and contribute their unique perspectives. We value openness, transparency, and continuous learning, and want to empower our employees to take ownership of their work while fostering a sense of community and teamwork. Whether you’re working in the lab, the office, or across functional teams, you will find an inclusive space where your contributions matter and your professional growth is supported.
Join us in shaping the future of biotechnology. Together, we can change lives.
Position:
We are seeking a motivated and detail-oriented Senior Research Associate / Associate Scientist to join the Biotherapeutics group and support antibody drug development programs. The successful candidate will independently design and execute antibody binding and immunoassay experiments, generate high-quality data, and maintain rigorous experimental documentation in a collaborative industry research environment.
Key Responsibilities:

• Independently design, perform, analyze, and troubleshoot antibody binding experiments using SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) platforms, including hands-on operation of Biacore, Octet, or Gator instruments, to characterize antibody–antigen interactions, binding kinetics, and antibody binning/epitope competition
• Perform FACS-based binding assays to evaluate antibody binding to cell surface targets and support functional characterization
• Develop, optimize, and execute ELISA assays in multiple formats (e.g., direct, indirect, sandwich, competitive) to support antibody drug development and characterization
• Perform data analysis and visualization using GraphPad Prism; interpret results and clearly communicate findings to project teams
• Maintain accurate, complete, and well-organized experimental records in electronic lab notebooks
• Collaborate with scientists and cross-functional team members to advance biotherapeutics programs
• Provide additional support for antibody drug development efforts as needed, including assistance with protein expression, purification, and other antibody characterization activities

• Bachelor’s or Master’s degree in Biology, Biochemistry, Biotechnology, or a related scientific discipline
• Minimum of 5 years of hands-on laboratory experience in a biotech or pharmaceutical industry setting – level commensurate to experience
• Demonstrated hands-on experience with antibody binding and characterization assays, including SPR (Biacore), BLI (Octet or Gator), ELISA, and associated data analysis
• Hands-on experience with flow cytometry/FACS-based binding assays for antibody characterization
• Proficiency in GraphPad Prism for data analysis, curve fitting, and visualization
• Strong data analysis, documentation, and organizational skills with high attention to detail
• Ability to work independently with minimal supervision and collaborate effectively in a team environment

• Experience with analytical characterization techniques, including HPLC-SEC, HPLC-HIC, and SDS-PAGE
• Experience with protein thermostability analysis (e.g., thermal shift/DSF or related methods)
• Experience with molecular cloning, protein expression, and protein purification
• Experience with antibody engineering (e.g., affinity maturation, humanization, Fc engineering, or related approaches)
• Familiarity with antibody discovery and biotherapeutics development workflows