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Twist Bioscience

Sr Technical Product Manager

Sorry, this job was removed at 06:09 p.m. (PST) on Tuesday, Dec 16, 2025
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In-Office
South San Francisco, CA, USA
155K-180K Annually
In-Office
South San Francisco, CA, USA
155K-180K Annually

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Sr Technical Product Manager  (Hybrid in South San Francisco , Portland or Carlsbad) 

About the Role:

We are seeking an experienced Senior Technical Product Manager with a strong background in life sciences, specifically in synthetic biology, mRNA, MRD, MGR, and DNA libraries, to join the Information and Business Technology (IBT) organization.  You will be the bridge between scientific experts and engineering teams, translating cutting-edge biological applications into actionable technical product requirements.  

We are looking for someone with a proven track record of maintaining effective business relationships to ensure IBT can deliver solutions that align with business strategies and objectives.  This role is crucial in shaping how scientific products and services are presented through innovative, user-centric digital platforms.  This role sits at the intersection of product, engineering, and business.  You’ll lead all aspects of product development from ideation through discovery and launch, and be comfortable taking on many different tasks to implement and ship your product.  

What You’ll be doing:

  • Engage and communicate effectively with diverse internal teams, including engineering, marketing, sales, operations, and customer support, to break down silos, synthesize insights from each group, and proactively identify and prioritize initiatives.  Ensure that product decisions anticipate and address emerging business needs, positioning the organization to stay ahead of market demands.
  • Develop and manage the IBT roadmap for your line of business, balancing competing priorities and in alignment with business needs and strategic objectives.
  • Gather and document detailed business requirements for projects, ensuring clarity and alignment across teams.
  • Demonstrate strong customer empathy and advocate for customer needs throughout the product development process.

What You’ll Bring:

  • Bachelor’s degree in Life Science, Engineering, or related scientific field; minimum of 5+ years of professional experience in a related discipline.
  • 5+ years of experience as a Business Systems Analyst (or in Technical Product Management), ideally supporting digital platforms in a biotech or life sciences field.
  • Proven ability to analyze, document, and translate complex business requirements into functional and technical specifications.
  • Strong background in system and process analysis, workflow design, and end-to-end solution delivery.
  • Demonstrated ability to facilitate user acceptance testing (UAT) and ensure business needs are met through system functionality.
  • Excellent communication, collaboration, and stakeholder management skills, with the ability to bridge business and technical teams.
  • Customer-centric mindset with strong problem-solving skills and a bias toward action in a fast-paced, agile development environment.

Preferred Qualifications:

  • Advanced degree (Master’s or PhD) in Life Science, Engineering, or related field.
  • Familiarity with scientific workflows (e.g., synthetic biology workflows, DNA/RNA library generation, MRD, MGF, or mRNA therapeutics).
  • Hands-on experience supporting or integrating eCommerce platforms with enterprise applications (Salesforce, SAP, or similar ERP/CRM systems).
  • Knowledge of development and code management systems (e.g., Jira, GitHub).
About Twist Bioscience

Twist Bioscience synthesizes genes from scratch, known as “writing” DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.

At Twist Bioscience, we work in service of people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.

Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.


The base cash compensation for this California-based role is below. In addition to base salary, this role is eligible for bonus, equity, and a generous benefits package. Final compensation amounts are determined by multiple factors, including candidate skill, experience, expertise, and location and may vary from the amount listed above. Compensation may be different in other locations.
San Francisco Bay Area Pay Range
$155,310$180,000 USD

Twist Bioscience San Francisco, California, USA Office

455 Mission Bay Blvd South, 6th Floor, San Francisco, CA, United States, 94158

Twist Bioscience South San Francisco, California, USA Office

681 Gateway Blvd, South San Francisco, CA, United States, 94080

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