Insitro Logo

Insitro

(VP) Senior Director Biologics Drug Discovery

Sorry, this job was removed at 06:15 p.m. (PST) on Tuesday, Oct 14, 2025
Be an Early Applicant
Easy Apply
In-Office
South San Francisco, CA, USA
Easy Apply
In-Office
South San Francisco, CA, USA

Similar Jobs

16 Minutes Ago
In-Office
San Jose, CA, USA
130K-276K Annually
Senior level
130K-276K Annually
Senior level
Artificial Intelligence • Hardware • Information Technology • Machine Learning
Develop and optimize embedded software for memory products, collaborating with hardware teams and supporting the testing solutions engineering process at Micron.
Top Skills: BashCC++Gnu ToolchainLinuxPciePython
16 Minutes Ago
In-Office
San Jose, CA, USA
93K-198K Annually
Mid level
93K-198K Annually
Mid level
Artificial Intelligence • Hardware • Information Technology • Machine Learning
As a Design Characterization Engineer, you will conduct pre-silicon simulations and post-silicon validations, collaborate on design features, and debug early silicon.
Top Skills: Bench Test EquipmentLogic AnalyzersO-ScopePythonTeradyne Magnum Test
16 Minutes Ago
In-Office
San Jose, CA, USA
90K-205K Annually
Senior level
90K-205K Annually
Senior level
Artificial Intelligence • Hardware • Information Technology • Machine Learning
As a Senior Category Sourcing Manager, you will lead supplier performance, manage procurement processes, negotiate contracts, and implement cost-saving initiatives within the semiconductor industry.
Top Skills: Cost Reduction InitiativesProcurement ProcessSupplier NegotiationsSupply Chain Management
The Opportunity

The heart of insitro's strategy is the combination of novel, cutting edge methods in machine learning, biology at scale and modality independent drug discovery that address key bottlenecks in the drug development pipeline. To accomplish that, we have put together an incredible team of highly talented drug discovery scientists who want to make a difference to these significant problems. In this key role, you will build and lead the Biologics Therapeutics capabilities at insitro within the Drug Discovery department.

You will be joining a well funded AI biotech that has established a pipeline of therapeutic candidates but yet is very much in formation, providing many opportunities for significant impact. You will work closely with a very talented team of Data and Machine Learning scientists, TA biologists and a growing CMC organization, learn a broad range of skills, and help shape insitro's culture, strategic direction, and outcomes. You will report to the Chief Scientific Officer and can be either onsite (3 days per week) in our South San Francisco office or hybrid (~1 week per month) in our office. Additional travel may be needed to relevant medical and translational science conferences and health authorities.

Join us, and help make a difference to patients!


Responsibilities
  • Guide therapeutic biologics efforts in projects as project team leader and subject expert
  • Build insitro's biologic therapeutic capabilities through extensive CRO and/or industry collaborations
  • Work cross-functionally to drive biologics projects through different stage gates towards clinical development candidates
  • Deeply engage cross-functionally to evaluate the suitability of new targets for prosecution by the biologics modality
  • Lead a Protein Sciences and Structural Biology team that can enable discovery biology and both large and small molecular modalities
  • Partner with Business Development and External R&D to evaluate new biotherapeutics technologies

About You
  • PhD in biochemistry, chemistry or cell biology with 10+ years of industry experience in drug discovery, and with 5+ years of direct experience in biologics drug design
  • Deep understanding of the biotherapeutic drug discovery process
  • Demonstrated track record of leadership advancing biologics projects through different stages of drug discovery and early-stage process and clinical development
  • Significant experience in enabling programs with protein reagents and structural biology
  • Proven leadership capabilities in cross-functional teams as a project team leader
  • First hand experience in using CROs and industry partner for biologics drug discovery
  • Experience in or exposure to computational approaches across the biologics design and bioprocess value chain
  • Track record of innovation and impact on projects through peer-reviewed publication and/or patent applications
  • Excellent written and verbal communication skills across multi-functional teams
  • Intellectual curiosity to push the boundaries of drug discovery

Compensation & Benefits at insitro

Our target starting salary for successful US-based applicants for this role is $247,000 - $316,000. To determine starting pay, we consider multiple job-related factors including a candidate's skills, education and experience, market demand, business needs, and internal parity. We may also adjust this range in the future based on market data.

This role is eligible for participation in our Annual Performance Bonus Plan (based on company targets by role level and annual company performance) and our Equity Incentive Plan, subject to the terms of those plans and associated policies.


In addition, insitro also provides our employees:

  • 401(k) plan with employer matching for contributions
  • Excellent medical, dental, and vision coverage as well as mental health and well-being support
  • Open, flexible vacation policy
  • Paid parental leave of at least 16 weeks to support parents who give birth, and 10 weeks for a new parent (inclusive of birth, adoption, fostering, etc)
  • Quarterly budget for books and online courses for self-development
  • Support to attend professional conferences that are meaningful to your career growth and role's responsibilities
  • New hire stipend for home office setup
  • Monthly cell phone & internet stipend
  • Access to free onsite baristas and cafe with daily lunch and breakfast for employees who are either onsite or hybrid
  • Access to free onsite fitness center for employees who are either onsite or hybrid
  • Access to a free commuter bus and ferry network that provides transport to and from our South San Francisco HQ from locations all around the Bay Area

insitro is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.

We believe diversity, equity, and inclusion need to be at the foundation of our culture. We work hard to bring together diverse teams–grounded in a wide range of expertise and life experiences–and work even harder to ensure those teams thrive in inclusive, growth-oriented environments supported by equitable company and team practices. All candidates can expect equitable treatment, respect, and fairness throughout the interview process.

#LI-Hybrid

Please be aware of recruitment scams: we never request payments, all recruitment communications are from @insitro.com, and if in doubt, contact us at [email protected].

About insitro
 
insitro is a drug discovery and development company using machine learning (ML) and data at scale to decode biology for transformative medicines. At the core of insitro’s approach is the convergence of in-house generated multi-modal cellular data and high-content phenotypic human cohort data. We rely on these data to develop ML-driven, predictive disease models that uncover underlying biologic state and elucidate critical drivers of disease. These powerful models rely on extensive biological and computational infrastructure and allow insitro to advance novel targets and patient biomarkers, design therapeutics and inform clinical strategy. insitro is advancing a wholly owned and partnered pipeline of insights and therapeutics in neuroscience and metabolism. Since launching in 2018, insitro has raised over $700 million from top tech, biotech and crossover investors, and from collaborations with pharmaceutical partners. For more information on insitro, please visit www.insitro.com.

Insitro San Francisco, California, USA Office

259 E Grand Ave, San Francisco, CA, United States, 94080

What you need to know about the San Francisco Tech Scene

San Francisco and the surrounding Bay Area attracts more startup funding than any other region in the world. Home to Stanford University and UC Berkeley, leading VC firms and several of the world’s most valuable companies, the Bay Area is the place to go for anyone looking to make it big in the tech industry. That said, San Francisco has a lot to offer beyond technology thanks to a thriving art and music scene, excellent food and a short drive to several of the country’s most beautiful recreational areas.

Key Facts About San Francisco Tech

  • Number of Tech Workers: 365,500; 13.9% of overall workforce (2024 CompTIA survey)
  • Major Tech Employers: Google, Apple, Salesforce, Meta
  • Key Industries: Artificial intelligence, cloud computing, fintech, consumer technology, software
  • Funding Landscape: $50.5 billion in venture capital funding in 2024 (Pitchbook)
  • Notable Investors: Sequoia Capital, Andreessen Horowitz, Bessemer Venture Partners, Greylock Partners, Khosla Ventures, Kleiner Perkins
  • Research Centers and Universities: Stanford University; University of California, Berkeley; University of San Francisco; Santa Clara University; Ames Research Center; Center for AI Safety; California Institute for Regenerative Medicine

Sign up now Access later

Create Free Account

Please log in or sign up to report this job.

Create Free Account