Top Scientist Jobs in San Francisco, CA

As the Senior Data Scientist for AI & Model Risk, you will lead AI risk assessments, coordinate with stakeholders, evaluate AI system designs, and ensure compliance with risk management principles in financial services.

As a Senior Staff Data Scientist, you'll leverage data analysis and ML models to support SoFi's Home Loans growth. This includes high-level technical leadership, mentoring, stakeholder communication, and building data pipelines.

Lead subscription analytics for SoFi Plus: define engagement/retention metrics, run deep-dive analyses and experiments, build scalable data pipelines and ML models, create executive dashboards, and influence product strategy to grow subscription value.

Develop and evaluate generative and predictive deep learning models for protein and nucleic acid design; curate large biomolecular datasets; collaborate with computational and experimental teams to validate models and shape company ML strategy.

Seeking a Scientist II to improve and validate automated processes in a lab setting and support robotic system deployments at customer sites, ensuring smooth integration and performance.

Analyze blockchain data, creating efficient query solutions and fraud detection methodologies while ensuring data integrity and transforming customer data needs into actionable insights.

Design, develop, and validate new RNA sequencing products and library-prep workflows; run experiments to assess feasibility and performance; scale and automate production-ready processes; collaborate cross-functionally and guide technicians; drive product launches and measurable customer adoption.

Execute and optimize in vivo efficacy and PK/PD studies using human CDX and PDX tumor models in mice; design studies, collect and analyze tumor, tissue, and blood samples, present results to project teams, and collaborate cross-functionally to advance oncology programs.

Bench-facing translational research role supporting preclinical and early clinical oncology studies. Design and execute in‑vitro and ex‑vivo assays, validate clinical-stage assays, analyze genomic/proteomic data, collaborate across cross-functional teams, and translate clinical observations into preclinical experiments to support biomarker and therapeutic development.

Develop and scale mammalian cell culture processes for GMP applications, perform small- and pilot-scale bioreactor runs, optimize N-1 perfusion and intensified fed-batch processes, support tech transfer and GMP manufacturing, author technical and regulatory reports, and collaborate cross-functionally to advance biotherapeutics.

Hands-on, bench-intensive role to design and run high-throughput experiments characterizing electrochemical reactions at micro-electrode interfaces, develop electrochemical methodologies for high-density arrays, implement surface passivation to prevent fouling, collaborate with protein biochemists, microfluidics and CMOS engineers, and document and present R&D findings to technical leadership.

The role of Principal Scientist - Biotransformation involves leading research and development efforts in biotransformation methodologies.

As a Senior Mass Spectrometry Software Scientist, you will develop mass spectrometry data analysis solutions and guide client projects to improve biopharmaceutical R&D workflows.

As a Research Engineer/Scientist, you'll build infrastructure for AI impact research, collaborate with teams, and generate insights into societal issues of AI.

The Research Engineer will develop large language models, conduct research on model architecture, optimize training infrastructure, and lead research projects.

Lead advanced AI/ML research initiatives, developing novel algorithms and optimizing large-scale training systems. Mentor junior researchers and produce impactful research outputs.

Lead research and product development of document understanding and multimodal AI. Design and evaluate VLMs, RAG and retrieval systems; build benchmarks and datasets; ship production-ready components (table extraction, structure parsing, semantic indexing, multimodal QA); and work with engineering, product, and customers to deploy models and agentic workflows at scale.

Develop and deploy state-of-the-art computer vision models for medical imaging, focusing on training vision encoders for radiology applications and evaluating model performance across multiple modalities.

The Senior Coastal Engineer will lead coastal engineering projects, manage teams and budgets, mentor junior staff, and engage with clients, focusing on adaptation and flood risk management strategies in the San Francisco Bay Area.

The Scientist 3 will lead research on T cell biology in autoimmune diseases, advancing projects to early clinical development and collaborating with other labs. Strong expertise in immunology and experimental design is required.

The Research Scientist will design methods and experiments for AI control and monitoring, focusing on safety and robustness in advanced AI systems. Key tasks include developing monitoring techniques, researching layered control mechanisms, and collaborating with policymakers and industry experts.

Assist the research team in developing and evaluating domain adaptation methods for LLMs and AI systems focused on enterprise domains.

The role focuses on advancing AI voice agents through research in LLMs and audio models. Responsibilities include model prototyping, evaluation, and collaboration with engineering to bridge research and production systems.

The Senior Scientist will develop assays for high-throughput operations, design workflows, mentor staff, and collaborate across multi-disciplinary teams to support Veracyte's cancer diagnostic products.

The Research Scientist will design and develop innovative machine learning models to improve clinical intelligence, driving research from concept to validated results while collaborating with clinicians and engineers.