Top Senior Backend Engineer Jobs in San Francisco, CA

Build and scale backend infrastructure for Ambient AI in healthcare. Work across real-time clinical documentation, AI-driven billing automation, and clinical intelligence. Ship production systems, collaborate with clinicians and customers, maintain reliability, monitoring, and metrics, and operate across the full software stack.

Design and develop robust, scalable backend systems for an AI-powered platform, focusing on performance, security, and optimization of data pipelines.

Design, build, and scale backend services, APIs, and real-time systems supporting connected devices. Architect cloud infrastructure, handle device connectivity, data pipelines, authentication/authorization, observability, and collaborate with robotics, perception, mobile, and product teams to deliver reliable, high-performance production systems.

Design and build high-throughput backend services and APIs to ingest, evaluate, and serve agent telemetry at scale. Own API contracts and versioning, optimize ClickHouse OLAP schemas and queries for petabyte-scale reads, collaborate with platform/infra on reliability and scalability, and uphold high engineering quality.

Design and build reliable backend services powering clinical data, insurance billing, patient-facing infrastructure, and financial ledger systems. Scale high-integrity systems requiring idempotency, strong consistency, and pragmatic AI integration to automate provider workflows and enable personalized patient experiences.

Responsible for leading a team to improve developer productivity, managing projects, and ensuring high-quality code delivery while collaborating across teams.

As a Senior Backend Engineer, you will design and maintain scalable backend services, optimize system performance, and collaborate with frontend engineers on API integrations.

Senior Backend Engineer responsible for building, deploying, and monitoring backend applications. Collaborate with product and cross-functional teams to design/version APIs, build event-driven/asynchronous systems, improve performance and reliability, and drive CI/CD and observability best practices. Ship high-quality, well-tested features and support platform scalability and maintainability.

The Senior Backend Engineer will develop high-quality backend products using Rust and other systems languages, focusing on scalable solutions for data management and security.

Design and develop scalable Java applications using various frameworks, ensuring long-term maintainability and performance while collaborating with the front-end team.

The role involves designing and developing high-performance web apps, improving user interfaces, maintaining component libraries, and ensuring code quality through comprehensive testing and collaboration with other teams.

This role involves developing core payment services, designing robust ledgers, ensuring high-scale reliability, and maintaining compliance in a fast-paced environment.

The Senior Backend Engineer will build and operate backend systems for AI agents, focusing on reliability, API design, and data modeling, while enhancing code quality and performance in a fast-paced environment.

Design, build, and support features for a monetization platform while ensuring reliability and performance as a senior backend engineer.

Design and build highly scalable, available, and reliable backend systems for a Publisher Ads & Monetization platform. Collaborate with architects, product, engineering, and DevOps to architect solutions, ensure operational excellence, and optimize performance for billions of daily requests.

Senior Backend Engineer responsible for designing and building backend services and microservices for payment products. Work includes C++/C#/Java development, REST APIs, Informix/Postgres data stores, CI/CD, cloud deployments, encryption, TDD, and collaborative agile delivery with ownership of architecture and operational quality.

Lead design and scaling of content ingestion, metadata, and processing systems. Build reliable pipelines handling messy formats, collaborate with ML, security, and product teams, mentor engineers, and drive platform and AI/LLM integration for content workflows and quality.

Design, build, and scale event-driven, distributed backend systems in Python to extract and enrich metadata at massive scale. Lead architecture, mentor engineers, integrate ML/LLM components, optimize performance, and ensure observability and reliability across AWS-based pipelines.

The Backend Engineer will design and maintain scalable backend services, develop APIs, optimize data storage, and ensure system performance and reliability, collaborating with various teams.

Design, build, and scale backend services for payments and transaction processing. Lead projects and mentor engineers in a collaborative environment.

The Senior Software Engineer will design and develop scalable applications, enhance DevOps practices, and drive continuous improvement within infrastructure and systems.

The Senior Software Engineer will lead and support a team in developing reliable and scalable backend systems, collaborating on product development, and improving infrastructure for secure communication between services.

The role involves developing a decentralized darkpool with high-performance matching engine, cross-chain liquidity aggregation, and fault-tolerant architecture while ensuring cryptographic privacy and low latency.

Build and maintain Python-based state systems for real-time voice AI, integrate multiple LLM providers, write async high-performance code and tests, monitor production, design databases (SQL/NoSQL), implement auth, and build microservices on AWS/Kubernetes to ensure reliability and high availability.

Looking for a Senior Backend Engineer to build robust systems for a marketing automation platform. Responsibilities include designing and developing features, communicating with customers, and collaborating closely with the team.