Top Senior Backend Engineer Jobs in San Francisco, CA

Build and own scalable payments infrastructure for card issuing, transaction processing, and settlement. Design reliable integrations with Stripe, banking partners, and internal platforms using .NET, C#, Azure, DDD, CQRS, and event-driven architectures. Improve system reliability, observability, performance, security, and compliance while mentoring engineers and contributing to technical direction. Apply AI-assisted development across coding, testing, debugging, and engineering workflows.

As a Sr. Software Engineer, Backend, you will develop AI-powered solutions for clinical documentation and medical coding, collaborating with cross-functional teams to enhance SaaS products and deliver actionable insights for healthcare organizations.

Own and evolve the backend and Go networking engine for a consumer VPN product. Responsibilities include stabilizing production systems, developing account, subscription, server-selection, and WireGuard APIs, integrating payment and analytics platforms, improving security, testing, observability, documentation, and CI/CD, and collaborating with mobile, infrastructure, product, and operations teams.

Design and build Supio’s internal compliance platform from the ground up. Develop anonymization, de-identification, and pseudonymization pipelines for PII and PHI; implement comprehensive audit trails, access controls, compliance tracking, reporting, notifications, and remediation workflows. Partner with DevOps, engineering teams, and privacy leadership to meet regulatory requirements while supporting AI-driven legal workflows.

Develop and scale RESTful backend services and shared platform tooling using Java, Spring Boot, Postgres, AWS, and Kubernetes. Design resilient distributed systems, implement secure coding practices, and maintain automated testing. Collaborate with engineering leadership, product managers, and cross-functional teams while mentoring engineers and contributing to shared infrastructure. The hybrid role requires three in-office days weekly in Culver City or San Francisco.

Senior software engineer leading backend and platform architecture across cloud and on-premises deployments. Responsibilities include developing scalable distributed systems, optimizing databases and queries, owning technical roadmaps, resolving production issues, improving security and observability, mentoring engineers, and partnering with product, architecture, UX, cross-functional teams, and customers. The role focuses on security monitoring, threat detection, compliance workflows, and reliable data-processing services.

Design and deliver LLM-powered, agentic AI systems to automate customer support and compliance. Build scalable, secure backend infrastructure in Python and Go, integrate third-party models/APIs, implement grounding and guardrails, and measure performance. Lead end-to-end projects, mentor engineers, conduct code reviews, and participate in on-call and incident response to improve resolution times and reduce operational costs.

Develop scalable backend applications and robust APIs for Salesforce’s multi-tenant cloud platform. Responsibilities include architecture, implementation, testing, system integrations, large-scale cloud data processing, CI/CD, on-call support, and evaluating human- or AI-generated code. The role emphasizes AI-first engineering, advanced prompt engineering, secure AI agent integration, and maintaining reliable system context and engineering standards.

Lead backend development to scale and harden API infrastructures, implement unit testing playbooks, optimize core algorithms, support migration from Supabase to a robust cloud provider, ensure system reliability and scalability, collaborate with frontend and DevOps, and integrate AI workflows and RPA where applicable.

Build and optimize high-performance backend systems for an xOT security platform using Rust. Participate across development lifecycle, design scalable microservices, integrate third-party devices and data providers, incorporate AI tools, and improve observability and reliability through testing, debugging, and peer review.

Design, build, and operate scalable AWS-based backend services and APIs for the Collectors Vault. Own architecture and delivery, improve performance and reliability, mentor engineers, and leverage modern AI tools to accelerate development and engineering velocity.

Lead backend and full-stack work on the Payments team, building multi-gateway integrations (Stripe, PayPal), payment APIs, and customer payment UIs. Ensure secure, compliant (PCI-DSS) payment flows, reliability, observability, and scalability across AWS/Kubernetes microservices. Partner cross-functionally to design architecture, implement settlement/reconciliation, and maintain high availability.

Build and operate the Power Packs customer experience and backend services. Design data foundations, APIs, and integrations across platform services. Troubleshoot distributed systems, contribute full-stack plumbing as needed, improve observability and documentation, and collaborate with Product and partner teams to deliver scalable, multi-tenant marketplace capabilities.

Design, build, and deploy backend services for creative tools. Integrate with AWS, ensuring scalable and secure Python code for event processing and APIs.

Design, implement, and evolve complex backend features and architecture. Improve reliability, performance, and security at scale. Mentor engineers, participate in incident response, set backend standards, and integrate agentic AI into production workflows.

Lead the architecture, development, deployment, and reliability of scalable APIs for Afresh’s flagship AI ordering product. Partner with product, account management, and engineering teams to deliver integrated solutions, support the existing iPad application, and shape future product direction. Drive projects from conception through launch, enforce testing and release best practices, mentor junior engineers, participate in Agile ceremonies, and provide constructive code reviews.

Own backend and infrastructure systems powering AI shopping agents, including live checkout automation, large-scale product ingestion, search and ranking, deployment, monitoring, databases, and on-call operations. Build reliable systems for changing retailer environments, improve failure recovery, and ensure transaction correctness. Collaborate directly with the CTO in a fast-moving startup. Experience with production LLM agents, machine learning, e-commerce, payments, or fraud infrastructure is advantageous.

Lead development of security enforcement integrations that warn or block unsafe AI artifact installations, serve sanitized alternatives, and record audit events. Build reliable event-driven backend systems with queues, webhooks, idempotency, retries, back-pressure, approval flows, dry runs, audit logs, and rollback mechanisms. Integrate third-party security, infrastructure, and identity APIs, with potential future work on fleet-wide revocation controls and security platform integrations.

Design, build, and maintain scalable backend services and infrastructure for Roadie’s logistics platform. Identify performance bottlenecks, improve reliability, collaborate with Product, Data Science, and engineering teams, contribute to code reviews and technical practices, and own projects from concept through production.

Design, develop, and maintain scalable cloud-native backend applications using Node.js, React, and AWS services. Collaborate with cross-functional teams to support federal missions, troubleshoot complex issues, identify root causes, and deliver secure, high-performing solutions. The role also involves relational database and DynamoDB work, agile development, CI/CD practices, and adapting to new technologies.

Design, build, and maintain scalable backend services, APIs, databases, data flows, and infrastructure. Lead complex features from design through deployment while improving performance, observability, security, reliability, and testing. Integrate third-party systems, support cloud infrastructure and CI/CD practices, and provide technical mentorship and guidance to engineers.

Build and maintain backend services, APIs, and integration layers for a modular ecommerce platform. Integrate personalization, semantic and LLM search, DAM, PIM, SAP/HANA, ERP, analytics, and customer data systems. Use AI coding agents throughout development while validating code quality, security, performance, and reliability. Design scalable APIs, automated testing, observability, and reusable architecture while collaborating with internal teams, vendors, and implementation partners.

Designs, builds, and maintains scalable backend services, APIs, databases, data flows, and infrastructure. Leads complex features from design through deployment while improving performance, observability, security, testing, and reliability. Integrates third-party platforms, supports cloud infrastructure and CI/CD practices, and mentors engineers through technical guidance and knowledge sharing.

Lead the design, architecture, development, deployment, and optimization of scalable .NET backend systems processing millions of daily healthcare transactions. Mentor developers, guide technical decisions, improve CI/CD pipelines, implement secure APIs, and collaborate with product stakeholders. The role requires expertise in .NET, C#, ASP.NET Core, cloud-native AWS services, Kubernetes, microservices, distributed systems, testing, observability, and secure software development.

Design and build scalable backend services and RESTish APIs for a multi-tenant streaming platform. Develop customer- and enterprise-facing web server backends in Go, ensure web application security, and support highly available cloud systems. Conduct code reviews, troubleshoot issues, and improve performance, reliability, scalability, and maintainability across global services. The role requires experience with high-traffic web services, distributed architectures, containers, and CDNs.