Top Staff Software Engineer Jobs in San Francisco, CA

Lead technical strategy, architecture, and large-scale engineering initiatives for Uber’s Marketplace Segmentation domain. Design resilient, high-performance distributed systems supporting real-time matching, pricing, and marketplace optimization. Mentor senior engineers, establish engineering best practices, solve complex technical challenges, and align Product, Data Science, and executive stakeholders around technical roadmaps and strategic goals.

Lead the technical direction and development of Uber’s real-time marketplace matching optimization systems. Build and productionize machine learning and decision systems using reinforcement learning, deep learning, causal inference, optimization, and control methods. Formulate ambiguous problems, develop behavioral models, create simulation and experimentation frameworks, and deploy scalable online inference systems. Collaborate cross-functionally, lead 0-to-1 initiatives, improve marketplace performance, and mentor engineers.

Design and build scalable ML infrastructure and backend systems for high-impact marketplace applications. Lead architecture, solve complex low-latency and high-correctness problems, drive organization-wide framework adoption, and translate business requirements into technical roadmaps. Mentor engineers, promote engineering excellence, and develop or support ML models, foundational models, and LLMs using modern MLOps practices, Kubernetes, distributed workflows, and large-scale scheduling.

Design, build, and maintain scalable Salesforce Apex solutions supporting Sales and Customer Experience teams. Use AI coding assistants throughout development, apply Salesforce architecture and release-management practices, deploy with sf CLI, and build reliable production systems at scale. Improve deployed features, measure impact, document code, and contribute beyond Salesforce when needed. Translate ambiguous requirements into scalable technical solutions and business value.

The Principal Engineer will lead technical direction across multiple teams, design architecture for financial systems, mentor engineers, and drive multi-year transformations in the Money Group.

Lead the technical design and architecture of Gusto's Commerce Platform, mentoring engineers and ensuring service reliability while collaborating across teams.

As a Staff Software Engineer, you'll design, build, and test Gusto's core platform services, mentor engineers, and collaborate with various teams to solve complex engineering problems.

Define the architectural vision and roadmap for Okta’s UI platform infrastructure. Build scalable shared libraries, frameworks, reusable components, and design patterns that enable globally accessible, world-ready applications. Lead architecture reviews, cross-functional technical alignment, and implementation of foundational platform components. Mentor senior engineers, establish engineering best practices, and ensure technical quality, maintainability, and adherence to coding standards across distributed feature teams.

Own VSCO’s production GPU image-processing engine and its iOS/macOS integration. Lead rendering, shader, color-management, memory, performance, and imaging capabilities including RAW and large-image export. Define shared pipeline contracts, diagnose mobile graphics issues, mentor senior engineers, improve engineering workflows, and guide technical direction across Product, Design, and Engineering. The role requires deep GPU systems expertise, strong systems-language experience, mobile graphics experience, and proven AI-assisted developer workflows.

Lead the technical direction and architecture of the Foundations platform team, owning authentication, authorization, SSO, secrets management, tenancy, and core platform services. Design APIs, drive services through launch, make technical decisions, establish engineering standards, and mentor engineers without formal management authority. Partner with engineering and product leaders to align execution with priorities.

Lead technical direction, design, build, and operate Snap's large-scale service and compute infrastructure. Drive platform roadmaps, reliability, observability, CI/CD, and developer experience. Act as hands-on staff tech lead across cross-functional initiatives, mentor engineers, and shape infrastructure for an AI-first future.

Own the roadmap and technical direction for Ray Core, leading complex distributed-systems projects across multiple teams. Design and implement primitives involving scheduling, resource management, fault tolerance, concurrency, networking, storage, and performance. Remain hands-on in systems-oriented development and debugging while mentoring engineers, raising technical standards, and guiding Ray Core’s long-term architecture and production evolution.

Build and operate agentic AI systems for complex legal workflows, including document drafting, evidence review, workflow orchestration, backend services, evaluations, observability, and integrations. The role requires production software engineering, LLM application development, asynchronous systems expertise, and close collaboration with legal and product teams to deliver reliable systems.

Own the end-to-end real-time neuronavigation and autonomy software stack for a medical device. Develop computer vision, sensor fusion, robotics, machine learning, and C++ real-time systems for patient tracking, coil localization, autonomous treatment delivery, and safety controls. Lead robotic integration, testing, FDA design verification, software lifecycle documentation, and cross-functional technical direction. Mentor engineers and work onsite with sensors, robots, and test fixtures.

Design, improve, and operate large-scale GPU- and data-intensive simulation and ML training pipelines (Ray/Kubernetes/AWS). Build production APIs, SDKs, and tools, and optimize cost, reliability, and performance to validate autonomous-vehicle behavior.

Lead architecture and delivery of complex web and mobile product initiatives. Build React and React Native applications, scalable components, APIs, data models, and shared libraries. Establish engineering standards, improve testing, performance, security, and reliability, and optimize database queries. Mentor engineers, guide technical decisions, and partner with leadership and stakeholders to shape the product roadmap. This is a fully remote role supporting veterinary clinic operations and supply-chain workflows.

Lead architecture and production deployment of AI platforms across cloud and on-premises environments. Partner with enterprise architects, shape product strategy, resolve critical production issues, and implement scalable platform capabilities. Drive cross-functional alignment across Product, Engineering, DevOps, Security, ML, Customer Success, and Forward Deployed Engineering. Mentor senior engineers and improve deployment efficiency, reliability, security, observability, and scalability.

Build and ship AI products for enterprise clients as a highly autonomous individual contributor. Set technical direction, write production-ready code, own end-to-end technical outcomes, and work directly with senior client stakeholders to understand requirements and tradeoffs. Apply disciplined software engineering practices to frontier AI systems, including testable hypotheses, durable datasets, and reliable production deployments.

Design, build, and own high-throughput backend and infrastructure services for a healthcare AI agent platform. Ensure reliability, graceful degradation, observability, performance, and secure handling of sensitive patient data. Drive architecture and operate services end-to-end in production.

As a Staff Software Engineer, you will lead technical strategies, drive architectural decisions, mentor engineers, and develop consumer banking solutions using various technologies.

Develop and support scientific software, data solutions, dashboards, workflows, and integrations for drug discovery research. Partner with scientists to translate research needs into technical requirements, lead software projects and technical workstreams, manage scientific data, support research cloud environments, and improve platform usability and reliability. The role also includes technical mentoring, architecture participation, data analysis, documentation, and operational support.

Build and own backend systems for Sleeper Picks, including contests, pricing, market data, settlement, wallets, ledgers, eligibility, and compliance. Develop reliable real-time systems handling high traffic, concurrent writes, financial correctness, reconciliation, and third-party integrations. Partner with risk, trading, design, and mobile/web teams to deliver end-to-end features. Staff engineers additionally own architecture, elevate engineering standards, and mentor peers.

Build and own backend systems for fantasy sports, including leagues, rosters, drafts, waivers, trades, matchups, and scoring. Scale real-time stat ingestion and low-latency delivery to millions of users. Ship features end to end with product, design, mobile, and web teams. Maintain production health through monitoring, profiling, and capacity planning. Staff engineers additionally own architecture, conduct reviews, and mentor engineers.

Own the design, development, and automation of Coinbase’s routing infrastructure connecting services to Kubernetes backends. Build scalable capabilities using Envoy, Istio, Ambient Mesh, and SPIFFE; improve routing latency, reliability, and performance; enhance developer tooling with responsible AI; and collaborate with security, reliability, and observability teams to resolve complex distributed-systems issues.

Architects and deploys multimodal 2D/3D object detection and tracking models using camera, LiDAR, and radar data. Owns perception data collection, dataset development, evaluation pipelines, production monitoring, and the perception system roadmap. The role also requires cross-functional leadership and mentoring junior engineers.