GRAIL Logo

GRAIL

Data Engineer 1, Operational Technology - Operations #4941

Posted 3 Days Ago
Hybrid
Durham, NC
86K-106K Annually
Junior
Hybrid
Durham, NC
86K-106K Annually
Junior
Build and maintain data pipelines integrating laboratory instruments, automation systems, operational platforms, APIs, robotics, databases, and files. Develop SQL transformations, data models, validation checks, orchestration, monitoring, and alerting to support analytics, dashboards, troubleshooting, and AI systems. Document infrastructure and datasets for regulatory compliance while collaborating with engineering, laboratory operations, data science, and automation teams. This is an on-site role with on-call and occasional weekend or holiday support.
The summary above was generated by AI
Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.
 
We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges.
 
GRAIL is headquartered in the bay area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.
 
For more information, please visit grail.com

As a Data Engineer on the Operational Technology team, you will build and maintain the data pipelines that connect GRAIL's lab instruments, automation systems, and operational platforms to a trusted, well modeled data foundation. You will own well scoped ingestion and transformation pipelines end to end, partnering with systems engineers, lab operations, data scientists, and automation engineers to keep data flowing reliably from the lab floor to the analytics and AI systems that depend on it. This is a hands-on role for an engineer who is ready to take ownership of real data infrastructure and grow quickly in a fast paced, regulated environment. Expect to work alongside a talented and highly motivated team that moves quickly.

This role is based on-site in RTP, North Carolina, Monday through Friday. The position participates in an on-call rotation and may occasionally require weekend or holiday support for production incidents, maintenance, or critical deployments.

Responsibilities:

  • Build and maintain data pipelines that ingest and integrate information from laboratory instruments, automation systems, sequencers, operational platforms, APIs, autonomous robotics platforms, databases and file based data sources.

  • Support downstream analytics, reporting, and AI systems by delivering clean, trustworthy datasets and timely data extracts for troubleshooting, root-cause investigations and platform improvements.

  • Develop and optimize SQL and transformation logic to cleanse, standardize, and model raw instrument and production data into reliable, well structured datasets.

  • Build and support datasets and data models used by operational dashboards, analytics, process monitoring, troubleshooting, and governed AI enabled workflows.

  • Implement orchestration, testing, monitoring and alerting so that data failures, freshness issues, schema changes, and incomplete processing are identified early.

  • Implement data validation and quality checks to ensure datasets are accurate, complete, and reliable.

  • Document pipelines, data models, and datasets to support reproducibility and compliance with ISO, CLIA, CAP, NYS, GMP, and FDA requirements.

  • Continuously improve your technical skills and the team's engineering practices.

Required Qualifications:

  • Degree in Computer Science, Mathematics, Software Engineering, Data Science, Life Sciences, Physics or similar field.

  • 1+ years of relevant professional, internship, academic, or project experience in data engineering, analytics engineering, software development, or a related field, or equivalent practical experience.

  • Proficiency in SQL.

  • Working proficiency with one or more programming languages, such as Python, Rust, C++, or similar.

  • Basic understanding of ETL or ELT pipelines, relational databases, and structured or semi-structured data.

  • Strong attention to detail and a commitment to data quality, reliability and accuracy.

  • Ability to collaborate effectively in teams of technical and non-technical individuals, and comfortable working in a rapidly changing environment with dynamic objectives and fast iteration.

  • Ability to investigate technical problems methodically, continuously learn and communicate clearly.

  • A highly analytical mindset and eagerness to solve technical problems.

Preferred Qualifications:

  • Familiarity with data pipeline orchestration and transformation tools such as Airflow, dbt, or comparable technologies.

  • Familiarity with cloud data platforms, object storage and warehouses such as AWS S3, Redshift, Glue, Snowflake or comparable technologies.

  • Familiarity integrating AI/agentic tooling into the data engineering SDLC.

  • Experience with semantic data modeling, data lineage, and automated data quality testing. 

  • Familiarity with statistical methods or basic process analytics.

  • Exposure to manufacturing, clinical laboratory operations, diagnostics, or biotechnology.

  • Experience with version control systems such as Git and collaborative development practices.

  • Basic understanding of APIs, file transfers, networking and system integrations.

The expected, full-time, annual base pay scale for this position is $86K - $106K. Actual base pay will consider skills, experience, and location.


This role may be eligible for other forms of compensation, including an annual bonus and/or incentives, subject to the terms of the applicable plans and Company discretion. This range reflects a good-faith estimate of the range that the Company reasonably expects to pay for the position upon hire; the actual compensation offered may vary depending on factors such as the candidate’s qualifications. Employees in this role are also eligible for GRAIL’s comprehensive and competitive benefits package, offered in accordance with our applicable plans and policies. This package currently includes flexible time-off or vacation; a 401(k) retirement plan with employer match; medical, dental, and vision coverage; and carefully selected mindfulness programs.

GRAIL is an equal employment opportunity employer, and we are committed to building a workplace where every individual can thrive, contribute, and grow. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, gender, gender identity, sexual orientation, age, disability, status as a protected veteran, , or any other class or characteristic protected by applicable federal, state, and local laws. Additionally, GRAIL will consider for employment qualified applicants with arrest and conviction records in a manner consistent with applicable law and provide reasonable accommodations to qualified individuals with disabilities. Please contact us at [email protected] if you require an accommodation to apply for an open position.

GRAIL maintains a drug-free workplace. We welcome job-seekers from all backgrounds to join us!

HQ

GRAIL Sunnyvale, California, USA Office

GRAIL is headquartered in Sunnyvale, California, with locations in Washington, D.C., North Carolina, and the United Kingdom. We also have a number of employees who are working remotely. Our bay area office has a employees working in our labs, software engineering, clinical development and more.

Similar Jobs at GRAIL

82K-102K Annually
Mid level
Artificial Intelligence • Big Data • Healthtech • Machine Learning • Software • Biotech
The Equipment Engineer 2 supports the installation, optimization, and maintenance of manufacturing equipment, improving performance and compliance through engineering analysis and collaboration with cross-functional teams.
Top Skills: Automated Manufacturing SystemsCapCliaClinical Laboratory RegulationsControl SystemsFda 21 CfrGmp Quality Management SystemsIso 13485Iso 15189Next-Generation SequencingProcess Instrumentation
9 Days Ago
Hybrid
59K-72K Annually
Junior
59K-72K Annually
Junior
Artificial Intelligence • Big Data • Healthtech • Machine Learning • Software • Biotech
Support billing receivables and reimbursement analysis by compiling and reconciling data, producing recurring and ad-hoc reports, migrating dashboards, tracking revenue-cycle KPIs, and working cross-functionally to resolve billing discrepancies and improve revenue recognition.
Top Skills: BusinessobjectsGoogle SheetsExcelPower BITableau
9 Days Ago
Hybrid
86K-106K Annually
Senior level
86K-106K Annually
Senior level
Artificial Intelligence • Big Data • Healthtech • Machine Learning • Software • Biotech
Design, build, and maintain BI-ready datasets, dashboards, and monitoring tools for high-throughput lab operations. Implement process monitoring (SPC), ensure data quality and audit readiness, perform root-cause analysis, and partner with Data Science to deploy predictive models that improve throughput, quality, and compliance.
Top Skills: Amazon RedshiftAws GlueCoupaJmpManaged AirflowMinitabNetSuitePythonRS3SalesforceSnowflakeSQLTableauWorkday

What you need to know about the San Francisco Tech Scene

San Francisco and the surrounding Bay Area attracts more startup funding than any other region in the world. Home to Stanford University and UC Berkeley, leading VC firms and several of the world’s most valuable companies, the Bay Area is the place to go for anyone looking to make it big in the tech industry. That said, San Francisco has a lot to offer beyond technology thanks to a thriving art and music scene, excellent food and a short drive to several of the country’s most beautiful recreational areas.

Key Facts About San Francisco Tech

  • Number of Tech Workers: 365,500; 13.9% of overall workforce (2024 CompTIA survey)
  • Major Tech Employers: Google, Apple, Salesforce, Meta
  • Key Industries: Artificial intelligence, cloud computing, fintech, consumer technology, software
  • Funding Landscape: $50.5 billion in venture capital funding in 2024 (Pitchbook)
  • Notable Investors: Sequoia Capital, Andreessen Horowitz, Bessemer Venture Partners, Greylock Partners, Khosla Ventures, Kleiner Perkins
  • Research Centers and Universities: Stanford University; University of California, Berkeley; University of San Francisco; Santa Clara University; Ames Research Center; Center for AI Safety; California Institute for Regenerative Medicine

Sign up now Access later

Create Free Account

Please log in or sign up to report this job.

Create Free Account