Director of Functional Genomics

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Genentech!

We believe care should start before disease takes hold. As the Head of Functional Genomics, you will step into a pivotal scientific leadership role within our Translational Genomics and Proteomics (TGP) Center. Leading a world-class, multidisciplinary team, you will shape the scientific strategy and drive the execution of advanced functional genomics capabilities. Your work will directly bridge cutting-edge technology development and biological application to unlock breakthrough insights across our entire therapeutic portfolio.

Key responsibilities include:

• Drive Scientific Strategy: Define and execute the global Functional Genomics strategy to support target identification, disease biology, biomarker discovery, and drug development priorities.

• Lead High-Impact Capabilities: Oversee and advance large-scale capabilities in genome-wide screening, perturbation biology, cellular models, sequencing, and multi-omics data generation.

• Foster Cross-Functional Synergy: Partner closely with Research Biology, Computational Sciences, Translational Medicine, and Development Sciences to turn complex data into meaningful portfolio impact.

• Champion Technological Innovation: Evaluate, develop, and integrate emerging technologies—including laboratory automation and advanced screening platforms—to solve complex health challenges.

• Cultivate Top-Tier Talent: Lead, mentor, and inspire a high-performing organization, creating an inclusive and scientifically rigorous environment where individuals thrive and grow.

• Expand Strategic Collaborations: Establish and nurture external alliances with academic institutions, industry pioneers, and technology partners to keep Roche at the forefront of the industry.

You are a visionary scientific leader who thrives at the intersection of advanced technology and drug discovery. You possess deep scientific curiosity, a collaborative mindset, and a passion for developing people and leading through empowerment.

To be successful in this role, you bring:

• Advanced Scientific Foundation: A PhD in Genetics, Genomics, Molecular Biology, Cell Biology, Computational Biology, or a closely related scientific discipline.

• Proven Leadership & Research Experience: 10+ years of progressive experience within biotechnology, pharmaceutical, or advanced research environments, with a track record of leading high-performing scientific teams.

• Deep Domain Expertise: Robust experience in functional genomics, including hands-on or strategic familiarity with CRISPR-based perturbation, single-cell or multi-omics technologies, translational profiling, or arrayed-based screening automation.

• Strategic Influence: Exceptional communication and partnership skills, with a demonstrated ability to navigate matrixed environments and build consensus across diverse stakeholders.

• Innovation Mindset: A strong record of innovation—evidenced by publications, presentations, or technology development—and a passion for translating cutting-edge science into life-changing healthcare solutions.

Relocation benefits are available for this job posting.

The expected salary range for this position based on the primary location of South San Francisco, CA is $181,900 - $337,900.  Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.  A discretionary annual bonus may be available based on individual and Company performance.  This position also qualifies for the benefits detailed at the link provided below.

Benefits

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

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