Principal Bioinformatics Scientist II

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections,  where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.

This role is a vital part of our Bioinformatics team, which is dedicated to pioneering advanced computational solutions that drive innovation in molecular diagnostics. As a member of this team, you will bridge the gap between complex biological data and actionable clinical insights through robust software engineering and database architecture. You will have the unique opportunity to collaborate closely with a multidisciplinary group of wet-lab scientists, software engineers, and clinical researchers to deliver tools that have a global impact on patient care.

The Opportunity

As a Bioinformatics Scientist, you will lead the design and development of end-to-end computational solutions, from scalable backend database architectures to intuitive frontend interfaces. Your primary accountability is to build and optimize the digital infrastructure that powers our PCR assay development and large-scale genomic analysis.

• Architect Scalable Data Systems: Design and deploy robust database structures and APIs that ensure efficient processing and retrieval of massive biological datasets.
• Engineer Advanced Algorithms: Lead the R&D of high-performance algorithms and automated workflows specifically tailored for clinical diagnostic applications.
• Develop Full-Stack Solutions: Build user-friendly web applications and interactive visualization tools that allow scientists to explore complex "omics" data in real time.
• Modernize Computational Infrastructure: Leverage High-Performance Computing (HPC) and Linux environments to implement cutting-edge software engineering best practices, including version control and CI/CD.
• Drive Process Innovation: Research and integrate emerging technologies in computational biology to maintain Roche’s position at the forefront of molecular biotechnology.
• Translate Science into Software: Convert complex scientific requirements from wet-lab stakeholders into functional, high-quality code and reproducible documentation.

Who You Are

• Educational Background & Experience: You possess a Bachelor’s degree with 12+ years of related experience, a Master’s degree with 10+ years of experience, or a PhD with 7+ years of experience in Bioinformatics, Computational Biology, or a related field. (Relevant experience includes prior or post-graduate work, as well as adjusted academic lab training in the same line of work).
• Advanced Technical Polyglot: You are highly proficient in Python and R, with deep expertise in object-oriented programming, Linux systems, and managing high-performance computing environments.
• Strategic Matrix Collaborator: You excel at working within a matrixed organizational structure, effectively balancing priorities from multiple stakeholders across R&D, IT, and Quality teams.
• Influential Communicator: You possess a proven ability to translate intricate technical and algorithmic concepts for non-computational audiences, ensuring alignment between diverse scientific disciplines.
• Full-Stack Visualizer: You have a strong track record of developing frontend applications using modern frameworks (React, Angular, or Vue) to create intuitive interfaces for multidisciplinary project teams.

Relocation benefits are not being offered for this position

The expected salary range for this position based on the primary location of Pleasanton, CA  is $139,400 - $258,800 USD Annual. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.  A discretionary annual bonus may be available based on individual and Company performance. 

This position also qualifies for the benefits detailed at the link provided below.

Benefits

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.

Roche is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

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