Freenome Logo

Freenome

Research Associate I/II

Posted 12 Days Ago
Be an Early Applicant
In-Office
Brisbane, CA, USA
38-47 Hourly
Junior
In-Office
Brisbane, CA, USA
38-47 Hourly
Junior
Develop and validate NGS-based DNA assays, run and characterize automated assays, collect and analyze high-quality experimental data, collaborate with computational and engineering teams, present results, troubleshoot experiments, and improve lab processes in a regulated, high-throughput environment.
The summary above was generated by AI

About this opportunity:

At Freenome, you will help develop the assay technologies used to analyze patient samples and contribute to our mission of early detection and intervention in human disease. As a Research Associate I/II, you will provide experience in next-generation-sequencing (NGS)-based analyses of DNA. Starting with a prototype assay, you will contribute to developing and validating clinical-grade assays to measure complex, blood-based analytes. You will work closely with multiple teams including molecular research, computational science, automation engineering, and clinical operations to develop the assays in a regulated, high-throughput environment as well as identify ways to rapidly iterate and improve on existing methods to evaluate technologies that can enhance our end-to-end test performance.

The role reports to the Senior Manager and Staff Research Scientist. This role will be an Onsite role.

What you’ll do:

  • Apply knowledge of molecular biology, nucleic-acid biochemistry, and next-generation sequencing to develop assays for DNA.
  • Characterize automated assays by generating and analyzing experimental data.
  • Gather high-quality data, take detailed notes, and openly communicate on lessons learned while performing experiments.
  • Collaborate with research team and computational biologists, understand how data reflect underlying molecular biology, and contribute to analyzing data and generating study conclusions.
  • Present data in cross functional teams.
  • Participate in troubleshooting efforts and design experiments with some supervisor guidance.
  • Help with process improvements across the lab by thinking critically about the execution of all experiments.

Must haves:

  • Bachelors with 1+ years of relevant industry experience or Masters in molecular biology, or a related field.
  • Hands-on experience in NGS based assay development including sample preparation, library preparation, target capture, and sequencing.
  • Biological understanding of human cell-free nucleic acids, single-cell analysis methods, immunology, and/or cancer biology.
  • High attention to detail and ability to record accurate and detailed observations, assess impact, and perform troubleshooting as required.
  • Flexible and highly motivated to learn new skills and comfortable adapting to changing priorities.
  • Ability to manual pipette with high confidence, accuracy, and precision.
  • Clear and proactive communication skills and ability to collaborate effectively with team members in the same and adjacent disciplines.

Nice to haves:

  • Experience working in a regulated laboratory environment (CLIA, GLP/GCLP, IVD development).
  • Experience with automated platforms in plate-based, low-volume formats and/or microfluidics and experience working with automated liquid handlers.
  • Experience using ELN (electronic lab notebook) and LIMS (lab information management system).
  • Familiarity with programing in a scientific programming language (e.g., Python or R).

Benefits and additional information:

The US target range of our base hourly rate for new hires is $37.68 - $46.69. You will also be eligible to receive equity, cash bonuses, and a full range of medical, financial, and other benefits depending on the position offered.  Please note that individual total compensation for this position will be determined at the Company’s sole discretion and may vary based on several factors, including but not limited to, location, skill level, years and depth of relevant experience, and education. We invite you to check out our career page @ freenome.com/job-openings/ for additional company information.  

Freenome is proud to be an equal-opportunity employer, and we value diversity. Freenome does not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.

Applicants have rights under Federal Employment Laws.  

  • Family & Medical Leave Act (FMLA)
  • Equal Employment Opportunity (EEO)
  • Employee Polygraph Protection Act (EPPA)

California applicants please review the CCPA Notice at Collection here:

  • California Consumer Privacy Act (CCPA)

#LI-ONSITE

HQ

Freenome Brisbane, California, USA Office

Brisbane, CA, United States

Freenome South San Francisco, California, USA Office

279 E Grand Ave, South San Francisco, CA, United States, 94080

Similar Jobs

13 Days Ago
In-Office
Brisbane, CA, USA
38-47 Hourly
Junior
38-47 Hourly
Junior
Healthtech • Biotech
Perform NGS-based assay development and validation for DNA-based, blood analytes. Execute and characterize automated assays, gather and analyze experimental data, troubleshoot with guidance, present results cross-functionally, and support process improvements in a regulated, high-throughput lab.
Top Skills: Automated Liquid HandlersElnLibrary PreparationLimsMicrofluidicsNext-Generation Sequencing (Ngs)PythonRSample PreparationSequencingTarget Capture
3 Days Ago
In-Office
San Francisco, CA, USA
28-33 Hourly
Junior
28-33 Hourly
Junior
Biotech
Perform animal colony maintenance and genotyping, conduct small rodent surgeries (stereotactic injections, electrode implants), prepare primary cell cultures, run molecular biology assays (cloning, gels, westerns, RT-qPCR), and perform histology and microscopy (tissue sectioning, immunostaining, image processing). Maintain computerized records and follow safety/physical requirements.
Top Skills: Animal Colony MaintenanceCloningComputerized Record-KeepingElectrode ImplantationGel ElectrophoresisGenotypingHistologyImmunostainingLight MicroscopyPrimary Cell CultureProtein AssaysRt-QpcrStereotactic InjectionsWestern Blotting
3 Days Ago
In-Office
South San Francisco, CA, USA
Junior
Junior
Biotech
Support design and execution of small-scale and scale-up cell therapy process development experiments using the Cellares platform. Perform cell line maintenance, leukopak processing, gene modification, expansion, cryopreservation, equipment qualification, SOP/report authoring, data analysis, and routine lab tasks to advance automated cell therapy manufacturing processes.
Top Skills: Aseptic TechniqueBioreactorsCellares PlatformCgmp ManufacturingCryopreservationLeukopak ProcessingSemi-Automated Cell Therapy Instruments

What you need to know about the San Francisco Tech Scene

San Francisco and the surrounding Bay Area attracts more startup funding than any other region in the world. Home to Stanford University and UC Berkeley, leading VC firms and several of the world’s most valuable companies, the Bay Area is the place to go for anyone looking to make it big in the tech industry. That said, San Francisco has a lot to offer beyond technology thanks to a thriving art and music scene, excellent food and a short drive to several of the country’s most beautiful recreational areas.

Key Facts About San Francisco Tech

  • Number of Tech Workers: 365,500; 13.9% of overall workforce (2024 CompTIA survey)
  • Major Tech Employers: Google, Apple, Salesforce, Meta
  • Key Industries: Artificial intelligence, cloud computing, fintech, consumer technology, software
  • Funding Landscape: $50.5 billion in venture capital funding in 2024 (Pitchbook)
  • Notable Investors: Sequoia Capital, Andreessen Horowitz, Bessemer Venture Partners, Greylock Partners, Khosla Ventures, Kleiner Perkins
  • Research Centers and Universities: Stanford University; University of California, Berkeley; University of San Francisco; Santa Clara University; Ames Research Center; Center for AI Safety; California Institute for Regenerative Medicine

Sign up now Access later

Create Free Account

Please log in or sign up to report this job.

Create Free Account