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Genentech

Scientist 2, Translational CVRM

Posted 20 Days Ago
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In-Office
South San Francisco, CA, USA
86K-159K Annually
Senior level
In-Office
South San Francisco, CA, USA
86K-159K Annually
Senior level
Conducts in vivo experiments in rodent models of cardiovascular and cardiometabolic diseases to support drug discovery. Responsibilities include developing disease models, performing survival surgeries, administering compounds, collecting blood and tissues, phenotyping animals, analyzing experimental data, maintaining reproducible ELN records, and presenting findings to multidisciplinary teams. The role requires strong cardiovascular model expertise, including myocardial infarction, ischemia-reperfusion, transverse aortic constriction, echocardiography, and heart catheterization.
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The Opportunity

 The CVRM (Cardiovascular, Renal, and Metabolism) Translational Biology group within Genentech Research and Early Development (gRED) is seeking a highly motivated and well-trained individual to advance drug discovery research and development efforts by executing in vivo experiments in rodent models of cardiometabolic diseases. This position requires working closely with scientists in a multidisciplinary team. Our environment is exciting and fast paced, requiring you to be excellent at multitasking and easily adaptable to meet evolving goals. This is an exciting opportunity to join a growing CVRM biology group and make significant contributions. 

Key Responsibilities:

  • Establish and conduct experiments in relevant rodent models and optimize approaches to model disease processes and states which resemble human diseases

  • Generate high-quality experimental data to meet strict timelines and project goals.

  • Communicate key findings at project meetings and make recommendations for follow-up studies and prioritization.

  • Familiar with relevant scientific literature. Understand and apply relevant scientific knowledge to solving problems arising from the projects involved

  • Work collaboratively within multidisciplinary project teams

  • Generate, analyze, and document complex experimental data with a focus on high reproducibility, maintaining accurate Electronic Lab Notebook (ELN) records.

Who You Are

  • Bachelor’s degree in pharmacology, biology, or related fields with 6+ years of laboratory experience, OR a Master’s degree with 4+ years of experience in industry or academia

  • A detail-oriented researcher who is passionate about leveraging best disease modeling to accelerate our research and discovery

  • Hands-on experience with cardiovascular models (myocardial infarction/ischemia–reperfusion, transverse aortic constriction) and their phenotyping (echocardiography, heart catheterization). Proficient survival surgical skills in rodents

  • Experience with rodent handling, various routes of drug administration (intravenous, intraperitoneal, intramuscular and subcutaneous), non-terminal and terminal blood sampling and tissue harvest. 

  • Strong analytical, organizational and communication skills

  • Highly motivated, self-driven person, comfortable working independently or as team in a fast-paced environment

  • Willingness to learn new skills and rapidly adapt to changing priorities for multiple projects.

Preferred

  • Experience with other cardiometabolic disease models will be a plus.

Relocation benefits are available for this job posting.

The expected salary range for this position based on the primary location of South San Francisco, CA is $85,500 to $158,700.  Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.  A discretionary annual bonus may be available based on individual and Company performance.  This position also qualifies for the benefits detailed at the link provided below.

Benefits

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

HQ

Genentech South San Francisco, California, USA Office

1 Dna Way, South San Francisco, CA, United States, 94080

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