Scientist I, In Vivo Pharmacology – Tumor Intrinsic Biology

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.

Our In Vivo Pharmacology group in South San Francisco, CA has an opening for a motivated in vivo pharmacologist who is dedicated to the discovery and development of innovative cancer therapeutics. The scientist will execute in vivo efficacy and PK/PD studies to support novel cancer drug development programs in mouse tumor models. The scientist will work collaboratively in a project team setting with biology, medicinal chemistry, biologics, and DMPK scientists to advance oncology programs through the R&D pipeline.

Responsibilities:

• Execute and optimize efficacy/PK/PD studies utilizing human CDX and PDX tumor models in immunocompromised mice.
• Understand study designs and work towards independent study design planning for assigned/owned projects.
• Analysis of data and presentation of efficacy/PD results to project teams and stakeholders.
• Work closely with and support other pharmacology team members for in vivo studies across team projects.

Qualifications:

• Bachelor’s Degree or equivalent education with typically 5 years of experience, or Master’s Degree or equivalent education with typically two years of experience.
• Preference for  candidates to have a degree in, in vivo pharmacology and experience in a pharmaceutical or biotech industry setting.
• Proficient hands-on experience with in vivo tumor model study techniques, including anesthetization, biological sample collection (tumor, tissue, and blood sampling), cell/drug administration via different routes/sites (SC, IP, PO, IV), and tumor volume measurement.
• Strong attention to detail with excellent laboratory, record keeping, data analysis, and organizational skills
• Excellent computer skills with working knowledge of Microsoft Word, Excel, and Powerpoint.  Familiarity with graphing software (e.g., GraphPad Prism) and animal study workflow software (e.g., Studylog) a plus.
• Knowledgeable of human cancer cell line models and workflows preceding in vivo study execution.
• Proactive and flexible, with ability to manage multiple projects/studies at any given time, adapt to changing priorities, and meet deadlines in a fast-paced environment.
• Excellent verbal and written communication skills to a variety of audiences.
• Excellent team player with ability to work and build strong relationships with peers and cross-functional team members.

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future. ​

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​

• This job is eligible to participate in our short-term incentive programs. ​

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. 

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled. 

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