GeneDx (Nasdaq: WGS) delivers personalized and actionable health insights to inform diagnosis, direct treatment, and improve drug discovery. The company is uniquely positioned to accelerate the use of genomic and large-scale clinical information to enable precision medicine as the standard of care. GeneDx is at the forefront of transforming healthcare through its industry-leading exome and genome testing and interpretation services, fueled by the world’s largest, rare disease data sets. For more information, please visit www.genedx.com.
Summary
As a public and profitable company, we have ambitious plans to scale and enhance our products and services. We’re looking for software engineers who can work holistically to design strategic solutions that go beyond just writing code. A strong track record in understanding business needs, communicating effectively, and delivering impactful results is essential, along with leadership qualities to guide and inspire colleagues.
Job Responsibilities
As a Senior Software Engineer, you'll play a key role in advancing our technology platform and building software products that make a meaningful impact. You’ll have the opportunity to lead technical efforts spanning multiple months across a large-scale system. You'll be expected to propose novel solutions to real-world business challenges, work cross-functionally with engineering and non-engineering peers, and drive results that enhance our user experiences and business workflows.
Day to day tasks may include:
- Dive into unfamiliar code to troubleshoot or add a new feature
- Participate in feature development of larger projects
- Technically lead smaller projects
- Participate in Support tasks, including off-hours and weekend on-call rotations.
- Propose technical designs, considering standard patterns, tradeoffs, and maintainability
- Provide thorough and meaningful code reviews
- Work with legacy as well as novel code bases
- Prototype, develop, and debug new features
- Implement and maintain DevOps cloud patterns
People Manager
- No
Education, Experience, and Skills
- Proficiency in at least 3 software languages, with a demonstrated ability to quickly learn new ones as needed. Python is highly desired, but other languages such as C#, Java, Javascript/Typescript, or others are acceptable.
- 5+ years of experience developing back-end services and APIs in a distributed, service-oriented architecture.
- 5+ years of experience building large-scale front-end applications using modern frameworks (React highly desired, but Vue, or Angular are acceptable).
- 5+ years of experience with data modeling using multiple databases and storage types
- 3+ years of experience designing and deploying services in the cloud (e.g. AWS, GCP, Azure, OCI).
Bonus points for:
- Prior healthcare/health tech experience, or experience in other regulated industries, particularly with data privacy and compliance requirements
- Kubernetes
Certificates, Licenses, Registrations
- None
Physical Demands
The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodation may be made to enable individuals with disabilities to perform the essential functions.
- While performing the duties of this job, the employee is frequently required to stand; sit and use hands to finger, handle, or feel.
- Ability to stand, walk, and sit for extended periods.
Work Environment
- Work is primarily performed in a remote office setting.
- Extended periods of stationary computer work.
Acknowledgements
The above job description is not intended to be an all-inclusive list of duties and standards of the position. Incumbents will follow any other instructions, and perform any other related duties, as assigned by their supervisor.
#LI-REMOTE
~
Science - Minded, Patient - Focused.
At GeneDx, we create, follow, and are informed by cutting-edge science. With over 20 years of expertise in diagnosing rare disorders and diseases, and pioneering work in the identification of new disease-causing genes, our commitment to genetic disease detection, discovery, and diagnosis is based on sound science and is focused on enhancing patient care.
Experts in what matters most.
With hundreds of genetic counselors, MD/PhD scientists, and clinical and molecular genomics specialists on staff, we are the industry’s genetic testing experts and proud of it. We share the same goal as healthcare providers, patients, and families: to provide clear, accurate, and meaningful answers we all can trust.
SEQUENCING HAS THE POWER TO SOLVE DIAGNOSTIC CHALLENGES.
From sequencing to reporting and beyond, our technical and clinical experts are providing guidance every step of the way:
TECHNICAL EXPERTISE
- High-quality testing: Our laboratory is CLIA certified and CAP accredited and most of our tests are also New York State approved.
- Advanced detection: By interrogating genes for complex variants, we can identify the underlying causes of conditions that may otherwise be missed.
CLINICAL EXPERTISE
- Thorough analysis: We classify variants according to our custom adaptation of the most recent guidelines. We then leverage our rich internal database for additional interpretation evidence.
- Customized care: Our experts review all test results and write reports in a clear, concise, and personalized way. We also include information for research studies in specific clinical situations.
- Impactful discovery: Our researchers continue working to find answers even after testing is complete. Through both internal research efforts and global collaborations, we have identified and published hundreds of new disease-gene relationships and developed novel tools for genomic data analysis. These efforts ultimately deliver more diagnostic findings to individuals.
Learn more About Us here.
At GeneDx, we're driven by urgency and purpose: helping patients get diagnosed earlier. Our mission, to empower everyone to live their healthiest life through genomics, drives our team to make a tangible impact each day – and shapes our culture where high standards, strong teamwork, and meaningful ownership are the norm. We act with intention, support one another, and deliver work we're proud to put our names on.
Here’s what you can expect day to day:
1. Play like a champion (step up, redefine what’s possible, own it)
We bring energy, focus, and a bias for action. We step up, take initiative, and deliver on our commitments – with quality, speed, and care.
We push past the obvious. We challenge assumptions, raise the bar, and make thoughtful, decisive calls — choosing progress over perfection.
We stay curious, ask questions, and share direct feedback with respect. We adapt quickly and keep learning through collaboration and continuous improvement.
If you’re motivated by meaningful work, a fast-moving environment, and teammates who care deeply about outcomes, you’ll thrive at GeneDx.
Benefits include:
- Paid Time Off (PTO)
- Health, Dental, Vision and Life insurance
- 401k Retirement Savings Plan
- Employee Stock Purchase Plan
- Employee Discounts
- Voluntary benefits
- Programs for parents and parents-to-be
- We provide expert support for family planning, pregnancy, and postpartum care, including up to 22 weeks of fully paid parental leave (U.S.) and up to $25K annually for fertility, adoption, or surrogacy.
GeneDx is an Equal Opportunity Employer.
All privacy policy information can be found here.
Similar Jobs
What you need to know about the San Francisco Tech Scene
Key Facts About San Francisco Tech
- Number of Tech Workers: 365,500; 13.9% of overall workforce (2024 CompTIA survey)
- Major Tech Employers: Google, Apple, Salesforce, Meta
- Key Industries: Artificial intelligence, cloud computing, fintech, consumer technology, software
- Funding Landscape: $50.5 billion in venture capital funding in 2024 (Pitchbook)
- Notable Investors: Sequoia Capital, Andreessen Horowitz, Bessemer Venture Partners, Greylock Partners, Khosla Ventures, Kleiner Perkins
- Research Centers and Universities: Stanford University; University of California, Berkeley; University of San Francisco; Santa Clara University; Ames Research Center; Center for AI Safety; California Institute for Regenerative Medicine
