Pilgrim Logo

Pilgrim

Systems Integration Engineer

Posted 5 Days Ago
Be an Early Applicant
In-Office
Redwood City, CA, USA
Entry level
In-Office
Redwood City, CA, USA
Entry level
Adapt molecular biology workflows, including sample preparation, reagent handling, qPCR, and sequencing preparation, to automated biotechnology systems. Define operating requirements, establish bench baselines, design integration tests, troubleshoot failures across biology, fluidics, controls, and software, and verify repeatability. Maintain test plans, records, protocol versions, and instrument configurations to ensure reproducibility and track fixes.
The summary above was generated by AI
About Pilgrim:

Pilgrim is building America’s biology prime - engineering, manufacturing, and deploying advanced biotechnology for defense and national security. Our primary platform, ARGUS, is a fully autonomous system for detecting biological threats in near real time, from naturally occurring pathogens to engineered agents.

We engineer hardware for biology, turning breakthrough science into fielded capabilities. Based in Redwood City, our team brings together mechanical and electrical engineering, chemistry, and biology under one roof to deliver critical technologies to the people who need them.

About the Role:

As a Systems Integration Engineer/Scientist at Pilgrim, you’ll turn biological methods into automated workflows on ARGUS. You’ll adapt sample preparation, reagent handling, qPCR, and sequencing preparation to the system, troubleshooting failures across biology, fluidics, and controls. Working with scientists and engineers, you will translate scientific advances into integrated systems that perform reliably in the real world.

Responsibilities:
  • Adapt sample preparation, reagent handling, qPCR, and sequencing preparation methods to automated workflows on ARGUS.

  • Define operating requirements for those workflows, including sample and reagent volumes, timing, temperature, and contamination control.

  • Establish bench baselines and compare automated performance using recovery, inhibition, sequencing quality, and processing time.

  • Design and run integration tests from individual fluidic and instrument subsystems through complete sample-to-result workflows.

  • Isolate failures across biology, fluidics, sensing, controls, and instrument software; verify causes and fixes experimentally.

  • Test workflow repeatability across operating conditions and verify performance after changes to hardware, software, reagents, or protocols.

  • Maintain test plans, run records, protocol versions, and instrument configurations so failures can be reproduced and fixes tracked.

Qualifications:
  • Strong foundation in bioengineering, molecular biology, biochemistry, or a related field. MS or PhD is a plus, not required.

  • Experience adapting laboratory protocols to automated instruments, liquid handlers, or custom hardware.

  • Ability to troubleshoot biological workflows and instrumentation using assay results, sensor readings, instrument logs, and bench measurements.

  • Experience designing comparisons between bench and instrument performance, selecting controls, and setting measurable acceptance criteria.

Preferred:
  • Experience with laboratory automation, liquid handling, microfluidics, cartridge-based systems, or development and testing of scientific instruments.

Pilgrim is an equal opportunity employer. We do not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other characteristic protected by law. Certain positions require access to export-controlled information and are limited to U.S. Persons as defined by applicable export control regulations.

Similar Jobs

6 Days Ago
Hybrid
124K-155K Annually
Senior level
124K-155K Annually
Senior level
Aerospace • Artificial Intelligence • Cloud • Machine Learning • Software • Cybersecurity • Defense
Designs, integrates, tests, and manages complex aerospace environmental control systems. Responsibilities include system architecture trade studies, requirements development and validation, verification planning, system-level testing, technical presentations, and traceable technical documentation. The role requires mechanical systems engineering expertise, knowledge of stress, fluid dynamics, thermodynamics, and heat transfer, plus experience with requirements-based engineering and aerospace systems.
Top Skills: DoorsDoors Ng
24 Days Ago
In-Office
212K-318K Annually
Senior level
212K-318K Annually
Senior level
Aerospace • Artificial Intelligence • Machine Learning • Robotics • Software
Design and maintain C++ and Python software for complex cross-platform systems. Develop APIs, messaging interfaces, CI/CD workflows, and automated tests while integrating distributed real-time systems, simulation tools, and third-party hardware and software. Debug system-level issues involving threading, timing, and data flow, contribute to architecture, and collaborate across teams. The role requires active Secret clearance and supports potential progression to TS/SCI clearance.
Top Skills: AfsimC++C++14C++17C++20C++98/03CmakeConanDockerGitlab Ci/CdGrpcLinuxNgtsOmsPythonRestUciUnixWindowsZeromq
24 Days Ago
Hybrid
147K-216K Annually
Expert/Leader
147K-216K Annually
Expert/Leader
Aerospace • Artificial Intelligence • Computer Vision • Software • Analytics • Defense • Big Data Analytics
Develops and executes integration plans for space and ground systems supporting Space Force environmental monitoring capabilities. Leads integration across system-of-systems, system, segment, and element levels; researches requirements, technologies, and threats; and applies integration methodologies to remote sensing systems. The role also evaluates technical performance, schedules, costs, risks, contractor data, requirements, interfaces, and verification activities for satellite programs.
Top Skills: Dod 5000.01Dod 5000.02Environmental MonitoringEvmOverhead Persistent Infrared (Opir)Satellite BusesSatellite PayloadsSatellite SystemsSpace-Based Remote SensingSystems IntegrationTactical IsrTelemetryTiming And Control (Tt&C)

What you need to know about the San Francisco Tech Scene

San Francisco and the surrounding Bay Area attracts more startup funding than any other region in the world. Home to Stanford University and UC Berkeley, leading VC firms and several of the world’s most valuable companies, the Bay Area is the place to go for anyone looking to make it big in the tech industry. That said, San Francisco has a lot to offer beyond technology thanks to a thriving art and music scene, excellent food and a short drive to several of the country’s most beautiful recreational areas.

Key Facts About San Francisco Tech

  • Number of Tech Workers: 365,500; 13.9% of overall workforce (2024 CompTIA survey)
  • Major Tech Employers: Google, Apple, Salesforce, Meta
  • Key Industries: Artificial intelligence, cloud computing, fintech, consumer technology, software
  • Funding Landscape: $50.5 billion in venture capital funding in 2024 (Pitchbook)
  • Notable Investors: Sequoia Capital, Andreessen Horowitz, Bessemer Venture Partners, Greylock Partners, Khosla Ventures, Kleiner Perkins
  • Research Centers and Universities: Stanford University; University of California, Berkeley; University of San Francisco; Santa Clara University; Ames Research Center; Center for AI Safety; California Institute for Regenerative Medicine

Sign up now Access later

Create Free Account

Please log in or sign up to report this job.

Create Free Account