Lead the People Business Partner and Employee Relations functions, partner with executives on organizational design and talent strategy, and run enterprise talent programs (workforce planning, performance, promotions, succession). Serve as Sunnyvale HR site leader, drive culture, coach senior leaders, and collaborate with TA, Rewards, L&D, and Legal to scale people practices across the company.
Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.
We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges.
GRAIL is headquartered in the bay area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.
For more information, please visit grail.com
The Vice President, People is a strategic HR leader responsible for building and leading a high-performing team that enables business success through exceptional partnership, talent management, and organizational effectiveness. Reporting to the Chief People Officer, this role leads the People Business Partner organization, Employee Relations function, and enterprise talent programs, including workforce planning, performance management, talent reviews, promotion process, and succession planning.
As a key member of the People Leadership Team, the incumbent serves as a trusted advisor to senior executives, translating business strategy into people strategies that strengthen leadership capability, foster a high-performance culture, and build the organizational capacity needed to achieve the company’s ambitions. This role partners closely with leaders across Talent Acquisition, Total Rewards, Learning & Development, and Legal to deliver an integrated and scalable people strategy.
This role is based in Sunnyvale, California. It offers a flexible work arrangement, with the ability to work from GRAIL's office or from home. Our current flexible work arrangement policy requires that a minimum of 60%, or 24 hours, of your total work week be on-site. Your specific schedule, determined in collaboration with your manager, will align with team and business needs and could exceed the 60% requirement for the site. At our Sunnyvale campus, Tuesdays and Thursdays are the key days where we encourage on-site presence to engage in events and on-site activities.
Responsibilities:
- Build, lead, and develop a high-performing team of People Business Partners and Employee Relations professionals, creating an environment of accountability, collaboration, continuous learning, and exceptional client service.
- Set the vision, priorities, and operating model for the PBP organization, ensuring consistent, strategic partnership across the business.
- Coach and develop HR leaders to strengthen organizational capability.
- Partner with executive leaders on organizational design, leadership effectiveness, change management, and organizational health.
- Provide strategic counsel on business transformation, workforce planning, talent risks, and organizational capability.
- Leverage people analytics and insights to inform business decisions and measure organizational effectiveness.
- Serve as a trusted advisor to the CPO and other C-suite leaders on organizational design and culture transformation.
- Provide executive leadership for Employee Relations, ensuring fair, consistent, and legally compliant practices across the organization.
- Oversee complex employee relations matters, organizational changes, and workplace investigations while partnering with Legal to effectively manage risk.
- Foster a culture of trust, accountability, inclusion, and respect.
- Lead the company's talent management programs, including workforce planning, performance management, promotion processes, talent reviews, and succession planning.
- Ensure enterprise talent processes are consistent, data-driven, and aligned to business strategy while building strong leadership pipelines and supporting employee growth.
- Partner across the People function to continuously evolve talent practices that enhance performance, engagement, and organizational capability.
- Serve as a key member of the People Leadership Team, helping shape enterprise people strategy and culture.
- Serve as the HR Site Leader for our Sunnyvale HQ location.
- Collaborate with HR Centers of Excellence (COEs) to shape enterprise HR policies, programs, and practices, ensuring alignment to business strategy and global consistency.
- Champion organizational culture, values, high-performance culture, and employee experience across all levels of the company.
- Partner with the executive leadership team to define and execute enterprise-wide people strategies that support business performance and organizational health.
- Taking on additional responsibilities.
- Participating in cross-functional projects and initiatives.
- Adapting to new technologies, processes, or methodologies.
- Supporting other departments or teams during periods of high demand.
- Contributing to special projects or temporary assignments as needed.
Lead the People Partner Function
Strategic Business Partnership
Employee Relations
Talent Management Programs & Organizational Effectiveness
Enterprise Leadership
Adaptability and Growth Expectation
As our organization continues to evolve and grow, this role may require flexibility in responsibilities and duties. Roles will expand, shift, or be modified to meet changing business needs, strategic priorities, and organizational objectives.
This may include:
These job duties summarize the position's primary responsibilities. It is not intended to be a comprehensive or all-inclusive listing of duties and responsibilities. Contents are subject to change at the company’s discretion.
Required Qualifications:
- Bachelor’s degree in Human Resources, Business Administration, Organizational Psychology, or related field; Master’s or advanced degree strongly preferred.
- 20+ years of progressive HR experience, including 10+ years in senior executive HR leadership roles.
- Demonstrated expertise in talent management, organizational effectiveness and transformation, workforce planning, leadership development, performance management, succession planning, and employee relations.
- Proven success in coaching senior executives, leading organizational change, and developing high-performing HR teams.
- Strong knowledge of employment law, HR compliance, and risk management.
Preferred Qualifications:
- Ability to influence and build trust at the highest levels of the organization.
- Extensive HR leadership with strong business acumen and the ability to align workforce strategy with corporate objectives.
- Proven track record in leading HR teams, driving transformation, and managing complex workforce challenges.
- Exceptional communication, facilitation, and negotiation skills.
- Strong analytical and strategic problem-solving skills, with the ability to integrate workforce data and business insights for executive decision-making.
- Demonstrated ability to foster innovation, inclusion, and employee engagement.
- Unwavering commitment to ethics, integrity, and organizational values.
Physical Demands & Working Environment:
- Executive-level role with in-office presence required at least three days per week
- Extended hours and flexible availability required to support global business operations and executive priorities.
- Domestic travel required to engage with leadership teams and enterprise stakeholders.
The expected, full-time, annual base pay scale for this position is $236K- $339K. Actual base pay will consider skills, experience, and location.
This role may be eligible for other forms of compensation, including an annual bonus and/or incentives, subject to the terms of the applicable plans and Company discretion. This range reflects a good-faith estimate of the range that the Company reasonably expects to pay for the position upon hire; the actual compensation offered may vary depending on factors such as the candidate’s qualifications. Employees in this role are also eligible for GRAIL’s comprehensive and competitive benefits package, offered in accordance with our applicable plans and policies. This package currently includes flexible time-off or vacation; a 401(k) retirement plan with employer match; medical, dental, and vision coverage; and carefully selected mindfulness programs.
GRAIL is an equal employment opportunity employer, and we are committed to building a workplace where every individual can thrive, contribute, and grow. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, gender, gender identity, sexual orientation, age, disability, status as a protected veteran, , or any other class or characteristic protected by applicable federal, state, and local laws. Additionally, GRAIL will consider for employment qualified applicants with arrest and conviction records in a manner consistent with applicable law and provide reasonable accommodations to qualified individuals with disabilities. Please contact us at [email protected] if you require an accommodation to apply for an open position.
GRAIL maintains a drug-free workplace. We welcome job-seekers from all backgrounds to join us!
GRAIL Menlo Park, California, USA Office

GRAIL is headquartered in Menlo Park, California, with locations in Washington, D.C., North Carolina, and the United Kingdom. We also have a number of employees who are working remotely. Our bay area office has a employees working in our labs, software engineering, clinical development and more.
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