Top Systems Engineer Jobs in San Francisco Bay Area, CA

Own system-level architecture, requirements, traceability, integration, verification and validation strategy for medical software products. Lead risk management, reliability investigations, technical trade-offs, and cross-functional engineering efforts across software, algorithms, quality, regulatory, clinical, product, and operations teams. Improve systems engineering practices, support compliant software development, and mentor other systems engineers.

Supports the IHS Electronic Health Records Modernization program by designing, integrating, installing, configuring, testing, and maintaining biomedical and end-user devices. Develops solutions for complex device engineering, infrastructure, security, backup, and redundancy challenges; maintains technical documentation; collaborates with cyber and implementation teams; and may lead or mentor others. The role is fully remote, requires Oracle Health experience, and may involve up to 25% travel.

Build and own core agent runtime and developer/product surfaces: orchestration loops, context and memory management, tool integrations, secure sandboxed execution, data syncing, evals, and AI-native UX. Ship production-grade, observable, recoverable agents and work with design partners to define enterprise requirements, guardrails, and evaluation pipelines.

Leads spacecraft systems engineering across customer mission requirements, system-level budgets, feasibility studies, satellite assembly, integration, testing, verification, and validation. Coordinates Mechanical, Thermal, ADSCS/GNC, Propulsion, Electrical, Manufacturing, Mission Operations, and data product teams. Supports environmental, functional, and end-to-end testing, anomaly resolution, design reviews, and ground-system integration for satellite missions and constellations.

Build experimental applications and interactive tools for configuring experiments, monitoring execution, visualizing results, and capturing metadata. Integrate instrument APIs with SDKs, data services, backend systems, and automation workflows. Implement testing, logging, failure recovery, CI, packaging, and deployment improvements. Diagnose issues across application, performance, concurrency, native-code, and hardware layers while collaborating directly with scientists and engineers to deliver reliable software.

Designs, integrates, tests, and optimizes complex semiconductor equipment systems and subsystems. Defines requirements and architectures, evaluates prototypes and suppliers, troubleshoots engineering issues, supports system integration, and coordinates reliability testing. Collaborates across electrical, mechanical, physics, software, and algorithms disciplines while providing onsite and remote customer support. Requires semiconductor or equivalent experience, metrology equipment expertise, optical microscopy skills, and customer-facing technical demonstration experience.

Develops traceable compute and controls requirements for autonomous vehicle platforms, leads compute safety analyses including FMEDA and FMEA, drives architecture tradeoffs, and coordinates verification, validation, diagnostics, and functional safety activities. The role collaborates across hardware, software, firmware, manufacturing, safety, and test teams to qualify systems, investigate failures, and ensure compliance with ISO 26262 and ISO 21448.

Designs, develops, deploys, administers, and sustains MuleSoft Anypoint Platform and/or Informatica integrations in AWS GovCloud. Builds secure REST APIs and Mule applications, manages API gateways and lifecycle governance, implements authentication, monitoring, CI/CD, and data synchronization, and integrates Navy logistics and mission-partner systems. The role also performs testing, documentation, incident triage, performance tuning, RMF/STIG support, stakeholder coordination, and knowledge transfer.

Lead architecture, integration, deployment, security, and sustainment of the Informatica Data Governance Suite in AWS GovCloud. Design highly available and recoverable infrastructure, implement Infrastructure as Code and CI/CD, establish security and compliance controls, coordinate multidisciplinary engineering work, oversee testing and monitoring, manage technical risks, and transfer operational knowledge to NAVSUP personnel.

Leads solution architecture and engineering for a MuleSoft Anypoint Platform implementation in AWS GovCloud. Designs highly available, secure, recoverable infrastructure; establishes Infrastructure as Code, DevSecOps, CI/CD, monitoring, and configuration standards; guides API and data integration; and coordinates RMF/ATO, STIG compliance, testing, risk management, deployment, documentation, and production sustainment. Provides technical leadership, stakeholder coordination, Government briefings, and knowledge transfer to Navy personnel.

Implements, configures, deploys, and supports software platforms and HL7 interfaces. Troubleshoots operating systems, databases, VPN connectivity, and application integrations; manages customer support tickets, SLAs, documentation, and implementation timelines. Advises customers on technical requirements, collaborates across teams to improve reliability, and participates in an on-call rotation.

Own and evolve Jira, Aha!, and related product and engineering platforms. Configure workflows, permissions, schemas, dashboards, automations, integrations, and reporting while improving governance, data quality, reliability, and adoption. Partner with Product, Engineering, TPM, Finance, and IT teams to translate business needs into scalable systems. Lead implementations, migrations, platform lifecycle management, troubleshooting, documentation, training, and tooling evaluations.

Supports internal and customer infrastructure platforms through incident triage, systems administration, cloud provisioning, Kubernetes deployments, identity management, monitoring, security hygiene, and runbook execution. The role requires Linux, networking, scripting, Git, cloud, container, and SaaS administration skills, with opportunities to grow into environment builds, configuration changes, compliance work, and platform ownership. It is fully remote, U.S.-based, and supports government-related environments requiring Secret clearance eligibility.

Leads complex, multi-month infrastructure projects supporting AI research systems. Designs, builds, and operates reliable, scalable distributed infrastructure; partners with research teams; resolves performance bottlenecks; mentors engineers; drives cross-team technical alignment; and improves incident response, postmortems, and on-call processes. The role requires strong software engineering, cloud infrastructure, architectural decision-making, and technical leadership experience.

Designs, develops, deploys, and operates satellite ground station systems for commercial and U.S. Government programs. Responsibilities include RF and antenna architecture, link budget analysis, system requirements, interface definitions, technical documentation, cross-functional integration, customer solution development, proposals, cost estimates, risk assessments, and technical presentations. The role requires expertise in satellite communications, RF systems, ground infrastructure, and systems engineering, with desirable experience in DSP, modem design, waveform development, and FPGA-based signal processing.

Develops and validates safety-critical motor control systems for electric, fly-by-wire aircraft. Responsibilities include PMSM control, inverter PWM, position and velocity estimation, fault management, servo actuation, Simulink modeling, C/C++ implementation, dynamometer and aircraft testing, system tuning, requirements decomposition, and PIL/HIL verification.

Designs, integrates, and deploys electromechanical battery test equipment connected to high-voltage batteries and data acquisition hardware. Develops battery safety lab expansion plans, executes cell and battery testing, builds data pipelines and dashboards, and maintains equipment documentation and compliance for certification. Requires hands-on mechanical and electrical engineering, battery safety, sensing, data processing, CAD, and test equipment experience.

Own the technical infrastructure of Mixpanel’s marketing website and its integrations with Salesforce, marketing automation, CRM, and broader GTM systems. Build and maintain form submission experiences, webhooks, data pipelines, monitoring, alerting, and reliable lead-capture flows. Manage front-end implementation in Framer, technical SEO, accessibility, experimentation tools, and third-party integrations. Set the technical roadmap, reduce technical debt, coordinate concurrent workstreams, and translate marketing requirements into durable production systems.

Provide pre-sales technical leadership, solution design, demonstrations, proofs of concept, and deployment support for enterprise wired and wireless networking solutions. Design secure Wi-Fi, switching, routing, cloud-managed, and Zero Trust environments. Support post-sales escalations, channel partners, and customer success while relaying technical feedback to Product Management. Conduct RF planning, deliver technical training, and maintain expertise in enterprise networking trends and competitive products.

Responsible for full-stack engineering, focusing on responsive UI development, API design, and integration for investment applications while ensuring performance and usability across investment workflows.

Own sustaining engineering for vehicle body and closure systems across production and in-service autonomous vehicle fleets. Lead root-cause investigations, corrective actions, design changes, validation, engineering change requests, retrofits, and rework campaigns. Use fleet and production data to improve safety, durability, reliability, serviceability, manufacturability, and uptime while collaborating with development, manufacturing, service, quality, reliability, and suppliers.

Lead architecture and scaling of finance systems across Oracle Fusion and integrations. Drive AI-assisted development, design data models, build integrations (SQL/PLSQL, REST/SOAP), automate financial workflows, and translate accounting requirements into scalable technical solutions while partnering with business and data teams.

Build and maintain accessible, reusable React Native and web components for Rocket Money’s design system. Collaborate with designers and engineers on UI primitives, tokens, patterns, documentation, tooling, motion, and interaction quality. Improve accessibility, testing, adoption, migration support, and developer experience through reliable shared infrastructure, Storybook examples, technical documentation, and code reviews.

Build core 0-to-1 systems at the intersection of software, hardware, and finance. Responsibilities include designing abstractions for complex legacy systems, owning the full product lifecycle, developing full-stack products, and deploying production-grade LLM systems for loan underwriting, compliance, and document processing. The role emphasizes backend systems, infrastructure, architectural tradeoffs, customer-focused product development, and contributing to engineering culture.

Own end-to-end software architecture for humanoid robot applications, design modular, production-ready platforms integrating robotics frameworks, AI, cloud/edge, and hardware constraints; lead technical decisions, guide POCs to deployments, and mentor a small engineering team.