St. Jude Children's Research Hospital - ALSAC
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Architect - Enterprise AI (Memphis, TN / Coppell TX) or Remote in USA
St. Jude Children's Research Hospital - ALSAC
Architect - Enterprise AI (Memphis, TN / Coppell TX) or Remote in USA
Be an Early Applicant
Defines enterprise architecture standards and reusable patterns for AI, agentic AI, and AI-enabled applications. Guides model selection, agent design, security, governance, observability, evaluation, and cost management. Partners with engineering, data, security, enterprise architecture, and business teams to move AI solutions from concept to production. Develops proof-of-concept implementations, reference architectures, and AI lifecycle guidance while ensuring alignment with enterprise technology strategy.
At ALSAC you do more than make a living; you make a difference.Job Description
We like people who are different…because we’re different, too. As one of the world’s most iconic and respected nonprofits, we know what it’s like to stand out. That’s why we’re looking at you. Your background, perspective, and desire to make an impact set you apart. As we work to help St. Jude cure childhood cancer, we're calling on the game-changers, innovators and visionaries to join our family. Not just for the kids of St. Jude, but also for you. Because at ALSAC, we develop and celebrate our employees. So, bring your whole, authentic self and become part of our shared mission: Finding cures. Saving children.®
The Enterprise AI Architect is responsible for defining and evolving ALSAC's enterprise architecture standards for Artificial Intelligence (AI), Agentic AI, and AI-enabled applications. This role partners with technology and business teams to ensure AI solutions align with enterprise architecture principles and are scalable, secure, reliable, and maintainable.
The Enterprise AI Architect provides architecture guidance, develops reusable patterns and standards, and helps teams successfully move AI solutions from concept through production implementation. This role collaborates across stakeholders to evaluate technologies, establish best practices, and ensure AI investments support ALSAC's long-term technology strategy.
Essential Job Functions- Define enterprise architecture standards, reference architectures, and implementation patterns for AI, Agentic AI, and AI-enabled solutions.
- Partner with Enterprise Architecture, Engineering, Data, Security, and business teams to evaluate AI use cases, establish success criteria, and provide guidance on architectural tradeoffs, including model selection, agent design patterns, cost considerations, and responsible AI practices.
- Design and maintain reusable architecture patterns for AI gateways, Model Context Protocol (MCP) integrations, agent orchestration, enterprise knowledge access, retrieval architectures, and AI platform services.
- Establish architectural guidance for AI security, identity management, authorization, governance, compliance, and policy enforcement.
- Support adoption of AI development lifecycle (AI-DLC) practices through architecture reviews, standards, reference implementations, and implementation guidance.
- Define architectural approaches for AI evaluation, observability, monitoring, operational readiness, and cost management.
- Develop reference implementations and proof-of-concept solutions that accelerate delivery and help teams scale AI capabilities into production environments.
- Ensure AI and technology solutions align with enterprise architecture standards, strategic technology roadmaps, and long-term operational objectives.
- Collaborate with stakeholders to gather, analyze, communicate, and validate requirements impacting ALSAC's enterprise technology environment.
- Bachelor's degree in Computer Science, Information Systems, Engineering, or a related field.
- 10+ years of experience in enterprise architecture, solution architecture, systems integration, software engineering, or related technology disciplines.
- Experience designing and implementing AI, Generative AI, machine learning, or intelligent automation solutions.
- Experience developing architecture standards, reference architectures, and technology governance practices.
- Strong understanding of cloud platforms, application integration, enterprise security, and modern software architecture patterns.
- Ability to communicate technical concepts effectively to both technical and non-technical stakeholders.
- 5+ years of leadership, team lead, or architecture influence experience.
- Enterprise AI architecture expertise with Bedrock, MCP, AI Gateways, LangGraph/LangChain, RAG, and agentic AI platforms.
- Strong architecture and implementation experience across OpenShift/Kubernetes, and scalable AI infrastructure, including deployment, operations, and lifecycle management of long-running agents.
- Knowledge of large language models (LLMs), retrieval-augmented generation (RAG), agent frameworks, vector databases, and AI observability practices.
- Experience with responsible AI, AI governance, security, and compliance frameworks.
- Experience creating reusable frameworks, accelerators, and architecture guidance for enterprise technology teams.
ALSAC is committed to providing flexible work options. This role may be based in a hybrid schedule for candidates located near our Memphis, TN or Coppell, TX offices. For highly qualified candidates in other U.S. locations, remote work arrangements may be available.
Benefits & PerksThe following Benefits & Perks apply to Full-Time Roles Only.We’re dedicated to ensuring children and their families have every opportunity to enjoy life’s special moments. We’re also committed to giving our staff excellent benefits so they can do the same. - Core Medical Coverage: (low cost low deductible Medical, Dental, and Vison Insurance plans)
- 401K Retirement Plan with 7% Employer Contribution
- Exceptional Paid Time Off
- Maternity / Paternity Leave
- Infertility Treatment Program
- Adoption Assistance
- Education Assistance
- Enterprise Learning and Development
- And more
ALSAC is an equal employment opportunity employer.
ALSAC does not discriminate against any individual with regard to race, color, religion, sex, national origin, age, sexual orientation, gender identity, transgender status, disability, veteran status, genetic information or other protected status.
No Search Firms:
ALSAC does not accept unsolicited assistance from search firms for employment opportunities. All resumes submitted by search firms to any ALSAC employee or ALSAC representative via email, the internet or in any form and/or method without being contacted and approved by our Employee Experience team and without a valid written search agreement in place will result in no fee being paid if a referred candidate is hired by ALSAC.
St. Jude Children's Research Hospital - ALSAC San Francisco, California, USA Office
San Francisco, United States, 94104
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