Tempus AI Logo

Tempus AI

Senior Manager, Software Engineering (Data Architecture)

Posted 2 Hours Ago
Be an Early Applicant
Hybrid
Chicago, IL
150K-225K Annually
Senior level
Hybrid
Chicago, IL
150K-225K Annually
Senior level
Leads data engineers and architects while owning Tempus’s enterprise data model and data reliability. Integrates clinical, genomic, NGS, and radiology data across relational and NoSQL systems; establishes modeling, observability, quality, and documentation standards; and mentors teams through technical reviews. Partners with product and engineering leaders to prioritize work and uses AI-assisted development tools to improve modeling, testing, and pipeline delivery. Requires strong SQL, Python, modern data stack, healthcare data standards, data observability, and healthcare/genomics domain expertise.
The summary above was generated by AI

Passionate about precision medicine and advancing the healthcare industry?

Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.

About Tempus

Tempus is on a mission to create the world’s largest integrated dataset of clinical and molecular data. We believe that, through data, we can make a lasting contribution to cancer research and treatment. At Tempus, products are owned and developed by small, autonomous teams of developers, designers, data scientists, and product managers who work together to build a platform that is both nimble and innovative.


The Role

As Senior Manager, Software Engineering, you will lead and mentor a small team of data engineers and data architects, and you will own the enterprise data model and the reliability of the data it represents. You will design how clinical records, genomics, next-generation sequencing (NGS) laboratory data, and radiology data are integrated, and you will ensure that the data are accurate, traceable, and suitable for critical applications such as machine learning and clinical decision-making.

You will establish modeling standards, implement quality gates in data pipelines, and develop the team through design review, code review, and ongoing coaching. You will use development tools assisted by artificial intelligence (AI) to accelerate design, testing, and delivery.


What You Will Do
  • Lead and mentor a small team of data engineers and data architects by conducting design and code reviews, providing technical guidance, and fostering a culture of excellence in data architecture and data quality.
  • Own and evolve an enterprise data model with engineers, product managers, scientists, and operators, integrating structured data from clinical records, genomics, the NGS laboratory, and radiology across relational and NoSQL data stores. Author and maintain entity-relationship diagrams, data dictionaries, API specifications, and data-translation documentation at the conceptual, logical, and physical levels.
  • Apply modern data architecture best practices and patterns, and teach modeling standards, including third normal form, dimensional (star schema) design, and established healthcare data model standards such as FHIR, OMOP, and related standards.
  • Evaluate the completeness of source-system models and partner data through profiling, and resolve structural inconsistencies before they reach downstream consumers.
  • Design observability for the data ecosystem with BigQuery, dbt, Elementary, and Grafana, including monitors, alerts, dashboards, lineage, and traceability back to source systems.
  • Partner with product managers and engineering leads to prioritize the backlog, estimate work, and translate complex requirements into actionable technical tasks. Advance the use of AI-assisted development, including Cursor, Claude, and GitHub Copilot, to accelerate modeling, testing, refactoring, and pipeline development.

Why We Are Looking for You
  • You have a record of leading and mentoring a small team of data engineers and data architects, of setting standards, and of guiding design in a fast-paced environment. You can translate gaps in the data model and in data quality into clear recommendations for engineers, scientists, and other stakeholders.
  • You are an expert in the modern data stack, particularly dbt, SQL, and Python, and you have demonstrated exceptional SQL skills in an enterprise data warehouse. You are proficient in the use of AI coding assistants such as Cursor, Claude, and GitHub Copilot.
  • You have applied modern data architecture best practices and patterns, and you can guide a team in their use. You have strong experience with third normal form (3NF) and dimensional (star schema) modeling; with established healthcare data model standards such as FHIR, OMOP, and related standards; and with modeling tools such as Erwin, Vertabelo, or Lucidchart.
  • You understand ETL/ELT and business intelligence (BI) architectures, and you can explain the long-term implications of choosing among relational, massively parallel processing (MPP), and NoSQL technologies. You have architected solutions across more than one of these technologies.
  • You have practical experience with data observability (for example, Elementary and Grafana) and with profiling and correlation analysis to identify data-integrity problems.
  • You have domain experience in healthcare and next-generation sequencing, including clinical and genomic data.

Preferred
  • Deep knowledge of Google Cloud Platform (GCP) and BigQuery architecture.
  • Experience modeling NGS data output.
  • Experience in implementing master data, reference data, or metadata management.

Why Join Tempus

You will work at the intersection of software engineering and cancer research. In this role, you will lead a small team of data engineers and data architects and shape the data model and quality systems that make Tempus data reliable enough for research and clinical use.

$150,000 - $225,000


The expected salary range may vary for other locations. Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.

We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. 

Tempus AI Redwood, California, USA Office

Tempus AI Bay Area - Tempus Office Office

Our Redwood City office is located in a waterfront neighborhood at the heart of Silicon Valley, providing convenient access to tech hubs and boasting a thriving business scene. With excellent transport options and a range of dining choices, it's a dynamic hub for professionals and tech enthusiasts.

Similar Jobs at Tempus AI

2 Hours Ago
Hybrid
Redwood City, CA, USA
150K-235K Annually
Senior level
150K-235K Annually
Senior level
Artificial Intelligence • Big Data • Healthtech • Machine Learning • Analytics • Biotech • Generative AI
Leads strategy, product vision, roadmaps, and execution for custom AI products developed with Life Sciences partners. Manages the full lifecycle from ideation and proof of concept through development, launch, commercialization, and post-market evaluation. Partners with medical, AI, translational research, engineering, quality, regulatory, and commercial teams while translating customer needs into product requirements. Requires healthcare technology product strategy experience, AI product lifecycle expertise, partner management, and strong knowledge of drug development.
Top Skills: Artificial Intelligence (Ai)
2 Hours Ago
Hybrid
55K-70K Annually
Senior level
55K-70K Annually
Senior level
Artificial Intelligence • Big Data • Healthtech • Machine Learning • Analytics • Biotech • Generative AI
Maintains clinical laboratory quality systems and documentation, including Device History Records, SOPs, batch records, training matrices, and audit materials. Performs incoming material acceptance, quality metrics analysis, root cause investigations, corrective and preventive actions, deviation reporting, and document control. Coordinates quality activities with management and testing staff while ensuring compliance with CLIA, CAP, NYS-DOH, and FDA requirements.
Top Skills: Document Control SystemsElectronic Quality Management SystemsGoogle SuiteMS Office
4 Hours Ago
Hybrid
Mid level
Mid level
Artificial Intelligence • Big Data • Healthtech • Machine Learning • Analytics • Biotech • Generative AI
Leads project planning and execution for new assay development and product initiatives. Coordinates cross-functional teams, manages scope, timelines, resources, risks, deliverables, and change requests. Develops project dashboards and status reports, facilitates core team meetings, escalates tradeoffs, ensures regulatory and quality requirements are addressed, and incorporates lessons learned into future planning.
Top Skills: CapCliaCodaFdaGmpJIRAMicrosoft ProjectNysdohSmartsheet

What you need to know about the San Francisco Tech Scene

San Francisco and the surrounding Bay Area attracts more startup funding than any other region in the world. Home to Stanford University and UC Berkeley, leading VC firms and several of the world’s most valuable companies, the Bay Area is the place to go for anyone looking to make it big in the tech industry. That said, San Francisco has a lot to offer beyond technology thanks to a thriving art and music scene, excellent food and a short drive to several of the country’s most beautiful recreational areas.

Key Facts About San Francisco Tech

  • Number of Tech Workers: 365,500; 13.9% of overall workforce (2024 CompTIA survey)
  • Major Tech Employers: Google, Apple, Salesforce, Meta
  • Key Industries: Artificial intelligence, cloud computing, fintech, consumer technology, software
  • Funding Landscape: $50.5 billion in venture capital funding in 2024 (Pitchbook)
  • Notable Investors: Sequoia Capital, Andreessen Horowitz, Bessemer Venture Partners, Greylock Partners, Khosla Ventures, Kleiner Perkins
  • Research Centers and Universities: Stanford University; University of California, Berkeley; University of San Francisco; Santa Clara University; Ames Research Center; Center for AI Safety; California Institute for Regenerative Medicine

Sign up now Access later

Create Free Account

Please log in or sign up to report this job.

Create Free Account