Top Chief of Staff Jobs in San Francisco, CA

Partners with the Chief Product Officer to run operating cadences across Product, Design, and Engineering. Owns roadmap planning, OKRs, scorecards, executive communications, strategic initiatives, cross-functional alignment, and organizational effectiveness. Leads ambiguous initiatives from strategy through execution, drives accountability, supports recruiting and planning, and improves collaboration across distributed teams. Uses data and AI tools to improve decision-making and productivity while freeing the CPO to focus on product development.

Serve as the President’s strategic and operational partner, owning complex cross-functional initiatives across product, engineering, AI, and support. Resolve organizational bottlenecks, synthesize high-stakes insights, drive technical and operational execution, and represent the President when needed. Use AI agents, automation, analytics, and scenario modeling to increase decision velocity and organizational leverage. This high-impact individual contributor role requires strong technical fluency, executive communication, judgment in ambiguity, and close in-person collaboration in Foster City.

Chief of Staff candidates partner with founders and executives on strategic and operational initiatives. Responsibilities include analyzing business questions, building financial models, conducting market and financial analysis, managing cross-functional projects, preparing executive communications, establishing operating processes, and solving ambiguous problems. Candidates must have 2–4 years of experience at a top-tier consulting firm or investment bank, strong analytical and communication skills, and willingness to work in major startup hubs.

Chief of Staff supporting the executive team by managing schedules, high-priority projects, communications, meetings, and internal operations. The role coordinates with senior management and HR, addresses employee and company inquiries, maintains information-handling practices, and escalates security or policy violations. The ideal candidate is highly organized, self-motivated, detail-oriented, adaptable, and experienced in administrative work within a fast-paced startup environment.

Chief of Staff partnering with the CEO and founding team to drive company priorities, cross-functional initiatives, operating rhythms, fundraising support, metrics analysis, process improvement, hiring, and execution. The role operates across product, go-to-market, operations, and strategy in a remote, early-stage AI-native legal services company.

Own the CEO’s strategic execution, cross-functional initiatives, priority tracking, operational monitoring, executive communications, hiring infrastructure, and administrative support. Drive projects across Operations, Sales, and Marketing, identify risks, improve processes, maintain CRM and workflows, coordinate events, and build AI-enabled automations. Translate business needs into technical specifications and BRDs while supporting organizational growth and keeping the CEO’s office effective.

Leads as a strategic partner to the Chief Digital and Product Officer, driving complex digital, product, technology, and organizational initiatives from definition through execution. The role evaluates opportunities, develops business cases and roadmaps, aligns senior stakeholders, resolves obstacles, and ensures measurable outcomes across a decentralized manufacturing organization. It requires strong executive communication, analytical judgment, influence without direct authority, and comfort solving ambiguous problems.

Partners with the CEO and executive leadership to shape company strategy, lead strategic planning and cross-functional initiatives, improve organizational effectiveness, and drive execution. Oversees operating cadences, OKRs, forecasting, reporting, board and investor materials, resource allocation, and performance analytics. Collaborates across operations, R&D, sales, marketing, finance, and HR to align priorities, improve decision-making, and support strategic partnerships and fundraising.

Chief of Staff supporting co-CEOs across strategic projects involving product, engineering, operations, finance, partners, investors, and board activities. The role coordinates US and India teams, manages partner and investor communications, drives project execution, prepares meetings and materials, and applies independent judgment. It requires regular evening work with India, occasional travel to India, and a two-to-three-year commitment.

Chief of Staff to the CEO serving as a strategic thought partner and execution leader. Responsibilities include managing company priorities, driving cross-functional initiatives, improving executive information flow, supporting strategy and commercialization, preparing Board materials, coordinating leadership cadence, tracking decisions, and assisting with fundraising and investor communications. The role is onsite in San Leandro and requires strong strategic judgment, financial acumen, communication skills, and experience managing complex initiatives.

Partner with the founding team to turn strategic priorities into measurable results. Coordinate cross-functional projects, manage risks and blockers, establish goal-setting and performance rhythms, and drive high-visibility initiatives from concept through completion. Build lightweight processes, use AI tools to automate repetitive work, and take ownership of ambiguous business issues before transitioning solutions to growing teams.

Work closely with the CEO and leadership team to drive company priorities, manage operating cadence, coordinate meetings and events, conduct business analyses and market research, improve processes with AI tools, support office operations, and handle confidential and urgent tasks. The role spans engineering, sales, marketing, and operations while helping scale the company.

Manage the Enterprise Deployment team’s workflow, staffing, performance tracking, recruiting coordination, onboarding, meetings, OKRs, team gatherings, and cross-functional alignment. The Chief of Staff will optimize team efficiency, thoughtfully allocate people to projects, identify performance or coverage gaps, and serve as a trusted liaison to organizational leaders. This is a fully remote global role, with London preferred.

Serves as the President’s strategic right hand, managing daily priorities, inbox and Slack communications, calendar, meeting follow-ups, executive onboarding, travel logistics, board preparation, and cross-functional coordination. The role requires strong judgment, discretion, organization, project management, data analysis, presentation skills, and the ability to create structure in a fast-growing, ambiguous environment while providing candid executive support.

Serve as the CEO’s operational right hand, managing calendars and inboxes, preparing dashboards and financial summaries, maintaining SOPs, improving processes, coordinating teams, and resolving cross-functional issues. The role has decision-making authority over tools, timelines, request triage, and calendar conflicts while escalating major financial, commercial, and strategic commitments.

Chief of Staff supporting the CEO and leadership team with strategic planning, OKR and KPI tracking, market analysis, cross-functional initiatives, executive communications, investor and board materials, and governance activities. The role requires strong analytical, financial modeling, communication, project management, judgment, and stakeholder-influence skills in a fast-growing health technology startup.

The Chief of Staff partners with the CEO and executive team on corporate strategy, special projects, strategic planning, board and investor communications, and company-wide operating systems. The role drives cross-functional accountability, improves workflows and meeting cadences, prepares executive materials, supports fundraising and hiring initiatives, and manages the CEO’s project load and administrative infrastructure. This is an in-person San Francisco position requiring evening and weekend engagement as needed.

Serve as a strategic partner to Pinterest’s Ads General Manager and leadership team. Own executive operating rhythms, strategic planning, business reviews, decision forums, and organizational planning. Lead ambiguous, cross-functional initiatives across Product, Engineering, Data Science, Finance, Recruiting, and People. Develop executive communications, operating mechanisms, governance, accountability systems, and recommendations that improve execution, prioritization, investment decisions, and organizational effectiveness.

Own cross-business priorities, projects, deadlines, follow-through, stakeholder communications, executive correspondence, project-management systems, dashboards, calendar management, meeting preparation, and domestic and international travel logistics. The role also supports office operations, evaluates tools, creates processes, and serves as a proactive liaison for investors, executives, government officials, and external partners.

Own company, founder, hiring, event, and special-project operations for a rapidly growing startup. Responsibilities include managing the office, vendors, equipment, supplies, onboarding logistics, candidate experiences, travel, scheduling, events, research, and ambiguous cross-functional tasks. The role requires exceptional resourcefulness, organization, judgment, communication, attention to detail, and the ability to act independently without a playbook.

Founding Chief of Staff responsible for building Oath Technologies’ early operational infrastructure. Duties include coordinating with the fiscal sponsor, managing budgets and finances, establishing systems, leading hiring and onboarding, handling people operations, administering vendors and partners, and preparing board and stakeholder materials. The role works closely with the CEO and is expected to grow into Head of Operations or COO-level leadership as the organization expands.

Serve as an extension of the CEO and own company operating cadence, including OKRs, leadership meetings, decision logs, and action-item follow-through. Manage commercial and fundraising follow-up, investor updates, board preparation, hiring operations, vendors, compliance, office needs, and other unowned priorities. The role is in person in San Francisco Monday through Thursday, includes travel, and is designed to develop into a senior operational or executive-operations leadership position.

Volunteer Chief of Staff supporting Co-Executive Directors with strategic planning, OKRs, organizational alignment, stakeholder communications, program evaluation, fundraising, and execution. The role coordinates cross-functional teams, develops action plans for political data initiatives, monitors political strategy and major races, prepares leadership meetings and external engagements, reviews team output, and provides status reporting. Requires 8–12 volunteer hours weekly, primarily during work hours, and is remote within the United States.

Chief of Staff supporting the CEO by running leadership operating cadences, planning, reporting, board and investor communications, and cross-functional special projects. The role also maps internal workflows, builds and deploys AI agents using Claude, HubSpot, APIs, and company data, establishes automation standards, and drives adoption across functions. Candidates need strong analytical, writing, systems-thinking, judgment, and execution skills, with 4–8 years of relevant experience.

Partner with the CEO to drive the company’s highest-priority initiatives from strategy through execution. The Chief of Staff will lead cross-functional projects, support company planning and operating rhythms, analyze business challenges, prepare board and fundraising materials, assist with executive hiring, and temporarily own initiatives until a long-term owner is established.