Top Chief of Staff Jobs in San Francisco, CA

Serve as a strategic partner to the CEO by driving company-wide planning, execution, and alignment. Own high-priority cross-functional initiatives, improve operating cadences, prepare executive communications, identify risks and opportunities, and ensure decisions translate into measurable results across product, go-to-market, engineering, and operations.

The Chief of Staff amplifies the CEO’s impact by managing executive communications, operating rhythms, board and investor materials, annual planning, company goal-setting, and cross-functional strategic initiatives. The role coordinates executive meetings and offsites, develops dashboards and KPI reporting, supports M&A evaluations, and embeds AI into planning and decision-making workflows. It requires exceptional executive writing, analytical ability, project leadership, discretion, and strong relationships with senior leaders and board stakeholders.

Provide high-level administrative support to the CEO office in a Co-CEO model: manage complex calendars, coordinate domestic and international travel (commercial and private aviation), prepare briefing materials, oversee budgets/expenses, track projects and events, and liaise with stakeholders to streamline executive operations.

Partners with the Chief People Officer and People Leadership Team to execute strategic priorities, manage the People portfolio, oversee planning and budgets, prepare executive and Board materials, facilitate leadership offsites, coordinate engagement events, and lead confidential strategic initiatives.

Serves as a strategic partner to the CEO, leading cross-functional initiatives, launching growth opportunities, building management and reporting routines, and removing obstacles for business unit leaders. Requires strong analytical, financial modeling, executive communication, and AI automation skills. The role is based onsite in San Francisco and involves 10–30% travel, with potential progression to business unit leadership.

Lead strategic and operational execution for Databricks’ Marketing organization as advisor to the CMO. Translate company strategy into marketing plans, OKRs, and initiatives; improve AI transformation, ROI, analytics, planning, and organizational efficiency; manage CMO leadership forums, executive presentations, communications, and cross-functional priorities across a 250-person team.

Serve as strategic partner to the Global Head of Sales by preparing executive and board materials, facilitating decisions, aligning cross-functional teams, leading sales planning and reporting, analyzing growth opportunities, and driving the sales organization’s operating rhythm. Lead global sales strategy initiatives, executive communications, meetings, offsites, and projects across GTM, Finance, People, Legal, and product teams.

Two-year executive leadership program partnering with operating leaders, CEOs, and functional teams across vertical software companies. Own cross-functional value-creation initiatives spanning go-to-market, sales, marketing, pricing, customer success, finance, M&A integration, and business operations. Support executive decision-making, implement operating improvements, and help newly acquired companies establish priorities and operating rhythms. High performers may advance into CEO, C-suite, or headquarters leadership roles.

Supports the CEO and Chief of Staff across hiring pipeline management, executive scheduling, investor and partner communications, vendor and manufacturing coordination, contract administration, cap table and board materials, content creation, partnerships, and event logistics. The intern owns fast-moving workstreams, turns incomplete tasks into plans, and helps coordinate operations during the company’s first large-scale robot production run.

Serve as the CEO's strategic and operational right hand at an AI LegalTech startup: prepare executive/board/investor materials, build financial models and decks, contribute litigation expertise to product content, validate LLM-generated analyses, drive cross-functional execution, manage company operations (recruiting, vendor administration, OKRs), represent the CEO, and handle special projects across finance, legal, and partnerships.

Serve as a force multiplier for the founders across go-to-market, operations, and strategy. Build and close sales pipeline through outbound, conferences, referrals, and partnerships; translate customer feedback into product decisions; prepare investor and partner conversations; and own internal administrative initiatives. The role requires startup operating experience, AI fluency, proven 0-to-1 go-to-market execution, strong communication, decisive problem-solving, and a high bias toward action.

The Chief of Staff supports executive leadership by facilitating strategy planning, executive operating rhythms, decision governance, board preparation, communications, and cross-functional initiatives. This role tracks enterprise priorities, coordinates strategic execution, prepares executive materials, facilitates senior-level discussions, and ensures decisions and action items are communicated and completed. The position requires strong influence, judgment, discretion, analytical ability, and insurance business acumen.

Lead strategic 0-to-1 initiatives supporting Schoolhouse’s 2028 vision, manage high-stakes relationships with partners and donors, and run the organization’s operating rhythm. The Chief of Staff will report to the President, drive cross-functional projects, improve workflows, support HR, legal, and finance activities, oversee hiring processes, and plan team retreats. The role requires strong judgment, communication, ownership, and comfort operating in ambiguity at a fast-growing nonprofit.

The Chief of Staff partners with the VP of Finance and Operations to run leadership meetings, prepare executive materials, track decisions, and drive follow-through. The role owns strategic and ad-hoc projects, manages cross-functional programs, develops business narratives, supports finance and operations leaders, conducts analysis, and makes recommendations. It requires strong financial modeling, communication, presentation, program management, and SaaS business knowledge.

Serve as the CEO’s strategic partner, owning company priorities, OKR planning, cross-functional special projects, board and investor communications, senior and clinical hiring, onboarding, and internal operating cadence. Lead ambiguous initiatives from analysis through launch, support fundraising and stakeholder engagement, and represent the company with partners and at industry events.

Works directly with the founder to translate company priorities into execution across hiring, operations, go-to-market, finance, and team systems. Brings structure to fast-moving workstreams, drives follow-through on critical decisions, and helps build scalable operating processes that support company growth and clarity.

Work directly with both founders to execute strategic initiatives across go-to-market, product, recruiting, and operations. Build and scale outbound and GTM systems, translate founder and customer insights into action, lead cross-functional special projects, create repeatable processes, and use AI tools and automation to increase team leverage.

The Chief of Staff will work directly with founders to drive strategic and operational priorities across customer communications, contracts, compliance, sales, partnerships, market research, recruiting, finance, and company operations. Responsibilities include coordinating SOC 2 compliance, managing vendors and legal work, supporting business development, representing the company externally, identifying bottlenecks, and converting ambiguous priorities into organized projects with measurable progress.

Serve as a strategic surrogate to the Chief Strategy Officer: represent the CSO in meetings, craft executive communications and presentations, drive cross-functional strategy initiatives, monitor progress and alignment, collaborate with engineering/product/sales, and articulate the Strategy org's impact internally and externally. Requires technical fluency, strong analytics, and executive presence to accelerate high-impact projects and customer engagements.

Serve as strategic partner to the SVP of Product to scale product leadership: run leadership rhythms, own headcount and budget planning, drive AI enablement, curate external product narrative, manage org-health metrics, and resolve cross-functional structural issues to increase decision speed and org effectiveness.

Serve as Chief of Staff to the CHRO, managing the People leadership operating cadence, leading cross-functional initiatives end-to-end, crafting executive communications, resolving issues proactively, and representing CHRO priorities across the organization.

Partners with the CEO and executive team to shape corporate strategy and operationalize priorities across the organization. Leads market and competitive analysis, annual strategy, KPI monitoring, executive meeting cadence, board and investor preparation, and cross-functional initiatives. Acts as connective tissue across Product, Sales, Engineering, Operations, Government Affairs, and Finance while managing ambiguous, sensitive projects and ensuring leadership alignment and follow-through.

Chief of Staff partnering with the CEO and CCO to drive high-priority commercial initiatives and accelerate U.S. growth. Responsibilities include market strategy, enterprise sales, strategic accounts, partnerships, pricing, product marketing, customer expansion, founder leverage, cross-functional problem solving, and building commercial operating cadences, metrics, feedback loops, and repeatable processes.

Serves as strategic partner to the President of Seramount, leading executive preparation, strategic prioritization, cross-functional initiatives, leadership operating rhythms, decision support, communications, organizational change, AI adoption, and employee engagement. The role translates strategy into coordinated execution, facilitates leadership decisions, and ensures commitments are completed across the organization.

Serves as a strategic partner to founders and executives by managing priorities, filtering decisions, translating vision into organizational action, preparing high-stakes meetings, synthesizing business reporting, coordinating stakeholders, identifying risks, supporting planning and resource allocation, drafting executive communications, managing confidential information, and leading special projects. The role also owns client satisfaction and evaluates whether engagements continue to meet evolving executive needs.