Top Senior Python Jobs in San Francisco Bay Area, CA

23 Days AgoSaved
Easy Apply
Hybrid
San Francisco Bay Area, CA
Easy Apply
187K-280K Annually
Senior level
187K-280K Annually
Senior level
Sales • Software • Travel
Own the specification, design, and implementation of features for FareHarbor’s large-scale web application. Collaborate with product teammates, develop scalable and performant full-stack solutions, improve automated testing, resolve technical issues, and participate in code reviews. The role requires strong Python and JavaScript skills, experience with front-end and back-end frameworks, relational databases, and production scalability challenges.
Top Skills: AngularjsDjangoJavaScriptPythonRelational DatabasesVue
Reposted One Month AgoSaved
Hybrid
San Francisco Bay Area, CA
230K-286K Annually
Senior level
230K-286K Annually
Senior level
Fintech • Machine Learning • Payments • Software • Financial Services
Lead diverse technology projects in distributed microservices and full stack systems, mentoring team members and collaborating with product managers on cloud-based solutions.
Top Skills: AWSCSSDockerGoGCPHTMLJavaJavaScriptKubernetesAzureNosql DatabasesOpen Source RdbmsPythonSQLTypescript
Reposted One Month AgoSaved
Hybrid
San Francisco Bay Area, CA
230K-286K Annually
Senior level
230K-286K Annually
Senior level
Fintech • Machine Learning • Payments • Software • Financial Services
Lead a team to develop distributed systems using Golang and Python on Kubernetes, collaborate on AI/ML solutions, and drive technological innovation.
Top Skills: AWSAzureCSSDockerGCPGoHTMLJavaJavaScriptKubernetesNoSQLPythonRdbmsSQLTypescript
8 Days AgoSaved
Remote
San Francisco Bay Area, CA
145K-150K Annually
Senior level
145K-150K Annually
Senior level
Digital Media • Software
Modernize legacy SAS data-processing systems by translating logic into scalable, high-performance Python solutions. Build and optimize large-scale data pipelines using formats including SAS, Parquet, JSON, and SQL. Integrate PostgreSQL, implement parallel processing, automated testing, data validation, and quality assurance, and maintain well-documented code. Collaborate with IT specialists and stakeholders to validate requirements, troubleshoot issues, and deliver cloud-native modernization solutions.
Top Skills: AWSDaskGitJSONLinuxMultiprocessingParquetPostgresPysparkPythonSASSQL
11 Days AgoSaved
Remote
San Francisco Bay Area, CA
Senior level
Senior level
Software
Lead the design, development, and operation of production-grade automation, agent frameworks, and CI/CD pipelines supporting documentation, localization, and language operations. Integrate platforms through REST APIs and MCPs, apply LLM capabilities responsibly, improve reliability and scalability, establish reusable standards, and mentor engineers. The role is fully remote in the US, with preferred Eastern or Central time zone availability.
Top Skills: Ai AgentsAzure DevopsChatgptCi/CdContainerizationCursorGitGitGithub ActionsGithub CopilotGitlab CiJenkinsJIRALinearLlmsMcpsMicrosoft CopilotObservabilityPythonRest Apis
Reposted 12 Days AgoSaved
Remote or Hybrid
San Francisco Bay Area, CA
Senior level
Senior level
Digital Media • Social Media • Software • Design
Design, develop, and maintain scalable Python applications; collaborate with cross-functional teams to deliver features; ensure performance and quality; identify and fix bugs; maintain code quality and automation; lead and mentor team members using agile practices.
Top Skills: Python
Reposted One Month AgoSaved
Easy Apply
Remote or Hybrid
San Francisco Bay Area, CA
Easy Apply
126K-248K Annually
Senior level
126K-248K Annually
Senior level
Big Data • Cloud • Software • Database
The Senior Python Engineer will develop and support MongoDB Python drivers, enhance library quality, and collaborate on product features.
Top Skills: Ai/Ml FrameworksMongoDBPypiPython
14 Days AgoSaved
Remote
San Francisco Bay Area, CA
100K-130K Annually
Senior level
100K-130K Annually
Senior level
Healthtech • Pharmaceutical • Hospitality
Build and maintain scalable backend applications, serverless functions, microservices, data workflows, ETL pipelines, and cloud-native architectures using Python and AWS. Manage databases, APIs, batch jobs, and real-time integrations while optimizing performance, scalability, security, compliance, and cost. Collaborate with product, engineering, analytics, and data teams; contribute to architecture, CI/CD, infrastructure automation, development standards, and technical mentorship. Healthcare claims data experience is required.
Top Skills: Amazon Api GatewayAmazon AuroraAmazon KinesisAmazon RdsAmazon RedshiftAmazon S3AWSAws GlueAws LambdaAws Step FunctionsCi/CdData LakesData WarehousesDevOpsETLHipaaHl7Infrastructure As CodeMicroservicesMySQLPostgresPythonServerless ComputingSQLStored Procedures
Reposted 26 Days AgoSaved
In-Office or Remote
San Francisco Bay Area, CA
160K-200K Annually
Senior level
160K-200K Annually
Senior level
Artificial Intelligence • Software • Energy
Lead end-to-end engineering initiatives for customer-facing features in a fast-paced startup. Build and maintain backend and frontend systems, design and evolve GraphQL APIs, debug production issues, participate in on-call rotation, and collaborate cross-functionally with product, policy, and commercial teams to deliver high-quality, scalable software for battery asset operations and project simulation.
Top Skills: AWSClaude CodeClojurescriptCursorDbtEchartsFulcroGithub CopilotGraphQLKotlinPostgresPythonPyTorchReactRechartsRedshiftSnowflakeStrawberryTailwind CssWarp Agent Mode
Reposted 28 Days AgoSaved
In-Office
San Francisco Bay Area, CA
Senior level
Senior level
Information Technology • Software • Big Data Analytics
We seek a Sr. Python Developer to work across various tech stacks, focusing on backend services and mobile app development while being adaptable and eager to learn.
Top Skills: Android AppsIos AppsJavaScriptNode.jsPostgresPythonRedis
25 Days AgoSaved
Remote
San Francisco Bay Area, CA
200K-225K Annually
Senior level
200K-225K Annually
Senior level
Artificial Intelligence • Computer Vision • Machine Learning • Analytics
Develop open source SDKs, enterprise APIs, UIs, and backend systems supporting large-scale computer vision datasets. Build scalable, maintainable, performant, and well-tested software for unstructured data and AI workflows. Contribute to enterprise deployments across customer clouds and on-premises environments, while improving tooling, automation, engineering practices, and open source community initiatives in a remote-first team.
Top Skills: DocumentdbElasticsearchMongoDBPythonTypescript
Reposted 26 Days AgoSaved
Remote
San Francisco Bay Area, CA
1M-2M Annually
Senior level
1M-2M Annually
Senior level
Agency • Information Technology • Software • App development
Design, develop, and maintain scalable Python applications and cloud-native solutions. Architect microservices, containerized deployments (Docker/Kubernetes), optimize cloud infrastructure, build CI/CD pipelines, integrate messaging systems, ensure security and high code quality, and mentor junior developers. Generative AI/ML experience is a plus.
Top Skills: AWSAzureAzure PipelinesCi/CdCosmosdbDjangoDockerFastapiFlaskGenerative AiGitlab CiGCPHugging FaceJenkinsKafkaKubernetesPythonPyTorchRabbitMQRdsRest ApisServerlessTensorFlowWebsockets
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Reposted 26 Days AgoSaved
In-Office or Remote
San Francisco Bay Area, CA
135K-155K Annually
Senior level
135K-155K Annually
Senior level
Machine Learning • Other
The Backend Software Engineer will develop and maintain backend systems for data processing related to coffee farming, utilizing Python and PostgreSQL. Responsibilities include feature development, problem-solving, and adapting systems to regulatory changes while ensuring system resilience.
Top Skills: AWSCi/CdDockerPostgresPostgresql/PostgisPythonTerraform
Reposted 26 Days AgoSaved
Remote
San Francisco Bay Area, CA
Senior level
Senior level
Artificial Intelligence • Information Technology • Professional Services • Software
The Senior Full Stack Developer will design, develop, test, and debug software solutions, collaborating with teams and optimizing applications. Responsibilities include user interaction design, back-end functionality, and ensuring software scalability and security.
Top Skills: CSSDjangoDockerFastapiFlaskGitGnu/LinuxHTMLJavaScriptMongoDBMySQLNode.jsOraclePostgresPythonReactSvnVue
Reposted 28 Days AgoSaved
Remote
San Francisco Bay Area, CA
Senior level
Senior level
Artificial Intelligence • Information Technology • Machine Learning • Software • Analytics • Consulting • Financial Services
Develop, test, and maintain a complex distributed processing application using Python and Java. Collaborate with product owners, data coaches, analysts, DBAs, and Agile teams to meet backend/frontend requirements. Work with distributed workloads (Spark/Hadoop), SQL/Snowflake, AWS, shell scripting, and job scheduling/process automation. Support delivery under Agile/SAFe practices and ensure alignment with program standards.
Top Skills: AWSBash/Shell ScriptingDroolsHadoopJavaLinux (Cli)OdmPythonSnowflakeSparkSQLVs Code
Reposted 28 Days AgoSaved
Remote
San Francisco Bay Area, CA
4K-5K Hourly
Senior level
4K-5K Hourly
Senior level
Travel
Lead development of Python-based web applications using Django and FastAPI, architect scalable solutions, and establish technical standards while mentoring developers and optimizing infrastructure.
Top Skills: Ai Coding AssistantsAWSDjangoFastapiGitPostgresPythonRailway
Reposted 28 Days AgoSaved
In-Office or Remote
San Francisco Bay Area, CA
Senior level
Senior level
Cloud • Software
The Python Engineer will write maintainable Python software, lead technical initiatives, collaborate globally, and contribute to community engagement at Canonical.
Top Skills: CC++DockerGoKubernetesLinuxNoSQLPythonRustSQL
Reposted 28 Days AgoSaved
In-Office or Remote
San Francisco Bay Area, CA
Senior level
Senior level
Digital Media
Develop and enhance features for EnrollWise, contribute to a scalable software architecture, review code, collaborate on design and technical feasibility, and maintain software quality.
Top Skills: ApolloAWSDjangoDjango OrmGraphQLNextjsPythonReact
Reposted One Month AgoSaved
In-Office
San Francisco Bay Area, CA
60K-80K Annually
Senior level
60K-80K Annually
Senior level
Artificial Intelligence • Information Technology • Software • Consulting
Develop and maintain Python applications performing SQL/CRUD operations, file extraction/transformation/generation (CSV, XML, JSON, PDF), and email integration. Collaborate in an onsite/offshore model, communicate clearly, and perform effectively under pressure for contract assignments.
Top Skills: CsvEmail IntegrationJSONPdfPythonSQLXML
One Month AgoSaved
Remote
San Francisco Bay Area, CA
Senior level
Senior level
Information Technology • Software • Consulting
Build and maintain full-stack wealth management platform features using Python and Angular or React. Design service-oriented architectures and REST/SOAP APIs, work with relational databases and ORMs, contribute to AWS or Azure cloud architecture, and deploy using container technologies. Collaborate in Agile/Scrum ceremonies, participate in code reviews and demos, and work independently with distributed teams.
Top Skills: AngularAWSAzureConfluenceDjangoDockerEcsFlaskJavaScriptJIRAJSONKubernetesMySQLOracleOrmPostgresPythonReactRestSoapSQLSQL Server
Reposted One Month AgoSaved
In-Office
San Francisco Bay Area, CA
Senior level
Senior level
Information Technology • Consulting
The Python Developer will manage stakeholder relationships, develop projects using Python and web frameworks, and collaborate on cloud technologies while ensuring standards are met and improved.
Top Skills: Apache SolrAWSAzureDjangoDockerElasticsearchFlaskGraphQLKubernetesMongoDBMySQLPostgresPythonSqlalchemyTornedo
Reposted One Month AgoSaved
Remote
San Francisco Bay Area, CA
Senior level
Senior level
Software
Senior iOS developer responsible for implementing native iOS features, improving user experience, participating in agile squads, conducting code reviews, troubleshooting customer issues, and helping modernize backend services on AWS. Collaborates with product and UI teams and documents technical knowledge while following best practices.
Top Skills: AWSCocoapodsiOSRestfulSwiftUikitXcode
One Month AgoSaved
Remote or Hybrid
San Francisco Bay Area, CA
170K-200K Annually
Senior level
170K-200K Annually
Senior level
eCommerce • Information Technology • Machine Learning • Marketing Tech • Database • Analytics • Big Data Analytics
Design and implement scalable backend and distributed systems for a marketing intelligence platform. Build near-real-time ingestion and processing, scale an incrementality/experimentation product, integrate AI-powered workflows, improve data ingestion/exports and connection-state systems, and contribute frontend components to deliver end-to-end product experiences.
Top Skills: AIAPIsData ProcessingDistributed SystemsMachine LearningMicroservicesPythonRbacReactReal-Time Data IngestionTypescript
Reposted One Month AgoSaved
Remote
San Francisco Bay Area, CA
165K-215K Annually
Senior level
165K-215K Annually
Senior level
Legal Tech • Software
Design and implement durable, fault-tolerant AI orchestration and backend systems using Temporal and agentic ReAct patterns. Deliver features end-to-end with testing, CI/CD, monitoring, and observability; mentor engineers and collaborate with cross-functional teams to translate legal workflows into reliable AI-powered features.
Top Skills: Async/AwaitClaude (Llm)Event-Driven ArchitectureFastapiGitlab Ci/CdMessage QueuesNew Relic ApmOctopus DeployPlaywrightPydantic V2Pydantic-AiPytestPython 3.12+ReactStructlogSyrupyTemporal
Reposted One Month AgoSaved
In-Office
San Francisco Bay Area, CA
115K-195K Annually
Senior level
115K-195K Annually
Senior level
Information Technology • Software • Database
Maintain and improve the LangChain Python package, enhance documentation, assist users, and build example applications.
Top Skills: Python
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