Top Senior Python Jobs in San Francisco Bay Area, CA

Reposted 18 Days AgoSaved
Hybrid
San Francisco Bay Area, CA
230K-286K Annually
Senior level
230K-286K Annually
Senior level
Fintech • Machine Learning • Payments • Software • Financial Services
Lead diverse technology projects in distributed microservices and full stack systems, mentoring team members and collaborating with product managers on cloud-based solutions.
Top Skills: AWSCSSDockerGoGCPHTMLJavaJavaScriptKubernetesAzureNosql DatabasesOpen Source RdbmsPythonSQLTypescript
Reposted 3 Days AgoSaved
Remote
San Francisco Bay Area, CA
1M-2M Annually
Senior level
1M-2M Annually
Senior level
Agency • Information Technology • Software • App development
Design, develop, and maintain scalable Python applications and cloud-native solutions. Architect microservices, containerized deployments (Docker/Kubernetes), optimize cloud infrastructure, build CI/CD pipelines, integrate messaging systems, ensure security and high code quality, and mentor junior developers. Generative AI/ML experience is a plus.
Top Skills: AWSAzureAzure PipelinesCi/CdCosmosdbDjangoDockerFastapiFlaskGenerative AiGitlab CiGCPHugging FaceJenkinsKafkaKubernetesPythonPyTorchRabbitMQRdsRest ApisServerlessTensorFlowWebsockets
Reposted 19 Days AgoSaved
Hybrid
San Francisco Bay Area, CA
230K-286K Annually
Senior level
230K-286K Annually
Senior level
Fintech • Machine Learning • Payments • Software • Financial Services
Lead a team to develop distributed systems using Golang and Python on Kubernetes, collaborate on AI/ML solutions, and drive technological innovation.
Top Skills: AWSAzureCSSDockerGCPGoHTMLJavaJavaScriptKubernetesNoSQLPythonRdbmsSQLTypescript
Reposted 7 Days AgoSaved
Remote
San Francisco Bay Area, CA
Senior level
Senior level
Artificial Intelligence • Information Technology • Professional Services • Software
The Senior Full Stack Developer will design, develop, test, and debug software solutions, collaborating with teams and optimizing applications. Responsibilities include user interaction design, back-end functionality, and ensuring software scalability and security.
Top Skills: CSSDjangoDockerFastapiFlaskGitGnu/LinuxHTMLJavaScriptMongoDBMySQLNode.jsOraclePostgresPythonReactSvnVue
Reposted 9 Days AgoSaved
Remote
San Francisco Bay Area, CA
Senior level
Senior level
Logistics • Software • Transportation
The Principal Python Engineer will design, build, and maintain backend services and APIs, focusing on system reliability and engineering quality. The role involves working with databases, applying DevOps practices, and leveraging AI for development efficiency.
Top Skills: DockerFastapiKubernetesPostgresPulumiPythonTemporalVue
Reposted 9 Days AgoSaved
In-Office or Remote
San Francisco Bay Area, CA
Senior level
Senior level
Cloud • Software
The Python Engineer will write maintainable Python software, lead technical initiatives, collaborate globally, and contribute to community engagement at Canonical.
Top Skills: CC++DockerGoKubernetesLinuxNoSQLPythonRustSQL
19 Days AgoSaved
In-Office
San Francisco Bay Area, CA
60K-80K Annually
Senior level
60K-80K Annually
Senior level
Artificial Intelligence • Information Technology • Software • Consulting
Develop and maintain Python applications performing SQL/CRUD operations, file extraction/transformation/generation (CSV, XML, JSON, PDF), and email integration. Collaborate in an onsite/offshore model, communicate clearly, and perform effectively under pressure for contract assignments.
Top Skills: CsvEmail IntegrationJSONPdfPythonSQLXML
Reposted 23 Days AgoSaved
In-Office
San Francisco Bay Area, CA
Senior level
Senior level
Information Technology • Consulting
The Python Developer will manage stakeholder relationships, develop projects using Python and web frameworks, and collaborate on cloud technologies while ensuring standards are met and improved.
Top Skills: Apache SolrAWSAzureDjangoDockerElasticsearchFlaskGraphQLKubernetesMongoDBMySQLPostgresPythonSqlalchemyTornedo
Reposted YesterdaySaved
In-Office
San Francisco Bay Area, CA
140K-320K Annually
Senior level
140K-320K Annually
Senior level
Artificial Intelligence • Software • Automation
Build and maintain React + TypeScript web applications and interfaces for AI agent control planes. Partner with designers to harden designer-written code, extend Python backend services and APIs, work in a Kubernetes-native distributed system, and explore agent-native interactive workflows across web and CLI.
Top Skills: KubernetesPythonReactTypescript
Reposted 3 Days AgoSaved
In-Office
San Francisco Bay Area, CA
115K-195K Annually
Senior level
115K-195K Annually
Senior level
Information Technology • Software • Database
Maintain and improve the LangChain Python package, enhance documentation, assist users, and build example applications.
Top Skills: Python
Reposted 23 Days AgoSaved
Easy Apply
Remote or Hybrid
San Francisco Bay Area, CA
Easy Apply
126K-248K Annually
Senior level
126K-248K Annually
Senior level
Big Data • Cloud • Software • Database
The Senior Python Engineer will develop and support MongoDB Python drivers, enhance library quality, and collaborate on product features.
Top Skills: Ai/Ml FrameworksMongoDBPypiPython
Reposted 5 Days AgoSaved
In-Office
San Francisco Bay Area, CA
120K-228K Annually
Senior level
120K-228K Annually
Senior level
Artificial Intelligence • Consumer Web • Digital Media • Software
Design, implement, and scale event-driven, distributed backend systems in Python on AWS to process and enrich large-scale document and media datasets. Lead technical projects, mentor engineers, integrate ML/LLM components, optimize performance, maintain observability, and collaborate with Data Science, ML Engineering, and Product to deliver reliable high-throughput content processing services.
Top Skills: AirflowAWSCloudwatchDatabricksDatadogEcsElasticacheLambdaLlmMachine LearningPythonScalaSnsSparkSqsTerraform
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Reposted 7 Days AgoSaved
In-Office or Remote
San Francisco Bay Area, CA
160K-200K Annually
Senior level
160K-200K Annually
Senior level
Artificial Intelligence • Software • Energy
Lead end-to-end engineering initiatives for customer-facing features in a fast-paced startup. Build and maintain backend and frontend systems, design and evolve GraphQL APIs, debug production issues, participate in on-call rotation, and collaborate cross-functionally with product, policy, and commercial teams to deliver high-quality, scalable software for battery asset operations and project simulation.
Top Skills: AWSClaude CodeClojurescriptCursorDbtEchartsFulcroGithub CopilotGraphQLKotlinPostgresPythonPyTorchReactRechartsRedshiftSnowflakeStrawberryTailwind CssWarp Agent Mode
Reposted 9 Days AgoSaved
In-Office
San Francisco Bay Area, CA
Senior level
Senior level
Information Technology • Software • Big Data Analytics
We seek a Sr. Python Developer to work across various tech stacks, focusing on backend services and mobile app development while being adaptable and eager to learn.
Top Skills: Android AppsIos AppsJavaScriptNode.jsPostgresPythonRedis
YesterdaySaved
Remote
San Francisco Bay Area, CA
Senior level
Senior level
Cloud • Information Technology
Lead development of a document-centric web interface integrating Vertex AI Search. Build React frontends and Python backends, implement document processing, vector search/RAG pipelines, optimize performance and scalability, write tests, and collaborate with cloud and architecture teams to deliver an enterprise-grade AI platform.
Top Skills: Agentic AiDjangoElasticsearchFastapiFlaskGoogle Cloud PlatformPineconePythonRagReactReact HooksRestful ApisState ManagementVector SearchVertex Ai Search
Reposted YesterdaySaved
Remote
San Francisco Bay Area, CA
Senior level
Senior level
Automotive
The Senior Software Engineer will build a large-scale data ingestion and classification system using web scraping, data processing, and search technologies, overseeing data extraction from various sources and developing search capabilities.
Top Skills: AirflowAWSElasticsearchKubernetesOcrOpensearchPythonScrapySpark
Reposted YesterdaySaved
Remote
San Francisco Bay Area, CA
Senior level
Senior level
Travel
As a Staff Software Engineer, you’ll lead the design and reliability of Duetto's data lakehouse, evolving data systems using Python and AWS, ensuring data quality, and implementing AI-driven solutions.
Top Skills: AirflowAWSDatadogDockerGithub ActionsGlueIcebergPysparkPythonSagemakerSentrySumo LogicTerraform
Reposted YesterdaySaved
Remote
San Francisco Bay Area, CA
141K-208K Annually
Senior level
141K-208K Annually
Senior level
Database • Analytics
Own and evolve ClickHouse's Python connector and SDKs; build and maintain integrations with orchestration and transformation tools; design AI/LLM integration patterns (RAG, embeddings, feature stores); engage with open-source community; collaborate with Product and Cloud teams to prioritize and ship production-grade data integrations.
Top Skills: Apache AirflowApache FlinkSparkAsyncClickhouseDagsterDbtFivetranKafka ConnectLangchainLlamaindexMultiprocessingN8NNumpyPandasPrefectPydanticPythonSQLSqlmeshThreading
Reposted 3 Days AgoSaved
Remote
San Francisco Bay Area, CA
139K-203K Annually
Senior level
139K-203K Annually
Senior level
Artificial Intelligence • Information Technology • Machine Learning • Marketing Tech • Software • Biotech • Design
Develop and maintain backend solutions, ensuring performance, security, and regulatory compliance, while collaborating in cross-functional teams.
Top Skills: AWSFastapiPython
Reposted 5 Days AgoSaved
Remote
San Francisco Bay Area, CA
Senior level
Senior level
Information Technology • Consulting
Design and build applications using Python, manage component design, optimize performance, and collaborate with clients on innovative products.
Top Skills: Ai ToolsCi/CdGitGoKubernetesPythonReact
Reposted 7 Days AgoSaved
In-Office or Remote
San Francisco Bay Area, CA
135K-155K Annually
Senior level
135K-155K Annually
Senior level
Machine Learning • Other
The Backend Software Engineer will develop and maintain backend systems for data processing related to coffee farming, utilizing Python and PostgreSQL. Responsibilities include feature development, problem-solving, and adapting systems to regulatory changes while ensuring system resilience.
Top Skills: AWSCi/CdDockerPostgresPostgresql/PostgisPythonTerraform
8 Days AgoSaved
Remote or Hybrid
San Francisco Bay Area, CA
Senior level
Senior level
Aerospace • Artificial Intelligence • Defense • Manufacturing
Develop and maintain flight and ground station software for satellite communications subsystems. Design and validate constrained-hardware platform applications, improve test coverage and documentation, contribute to architecture and peer reviews, and provide expert support to satellite operations.
Top Skills: BashCi/CdDockerGitGitlabGnu/LinuxHTTPKubernetesPythonTcp/Ip
Reposted 9 Days AgoSaved
Remote
San Francisco Bay Area, CA
Senior level
Senior level
Gaming • Software
As a Senior Full Stack Software Engineer, you will design and maintain the core platform for sports betting, developing APIs and frontend features, optimizing performance, and ensuring compliance while mentoring junior engineers.
Top Skills: Next.JsPythonReactTypescript
Reposted 9 Days AgoSaved
Remote
San Francisco Bay Area, CA
Senior level
Senior level
Artificial Intelligence • Information Technology • Machine Learning • Software • Analytics • Consulting • Financial Services
Lead Software Engineer responsible for designing, developing, testing, and maintaining a distributed processing application using Python and Java. Collaborate with product owners, data coaches, analysts, DBAs, and Agile teams to meet backend/frontend requirements, implement cloud and big-data solutions (Spark/Hadoop), and ensure program standards and reliable delivery.
Top Skills: SparkAWSDroolsHadoopIbm OdmJavaLinuxPythonShell ScriptingSnowflakeSQLVisual StudioVs Code
Reposted 9 Days AgoSaved
Remote
San Francisco Bay Area, CA
Senior level
Senior level
Artificial Intelligence • Information Technology • Machine Learning • Software • Analytics • Consulting • Financial Services
Develop, test, and maintain a complex distributed processing application using Python and Java. Collaborate with product owners, data coaches, analysts, DBAs, and Agile teams to meet backend/frontend requirements. Work with distributed workloads (Spark/Hadoop), SQL/Snowflake, AWS, shell scripting, and job scheduling/process automation. Support delivery under Agile/SAFe practices and ensure alignment with program standards.
Top Skills: AWSBash/Shell ScriptingDroolsHadoopJavaLinux (Cli)OdmPythonSnowflakeSparkSQLVs Code
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