Top Senior IT Jobs in San Francisco Bay Area, CA

Leads Engine’s distributed IT organization and modernizes its IT function. Responsibilities include managing engineers and support analysts, improving device lifecycle and endpoint security, architecting Okta-based identity and automation, overseeing onboarding and offboarding, establishing support SLAs, partnering with Security and People teams, reducing technical debt, and delivering cross-functional technology programs. The role is hands-on, combining strategic leadership with technical troubleshooting and execution.

Provides Tier 1 IT support for global associates, troubleshooting Windows and macOS endpoints, networks, identity and access, Microsoft 365, and software issues. Manages onboarding, offboarding, endpoint provisioning, and device administration using Intune, Autopilot, and Jamf. Documents resolutions, supports major incidents, escalates complex issues, and improves support processes. Requires up to 10% domestic and international travel and occasional after-hours support.

Provides high-touch, end-to-end IT support for Airbnb executives and Executive Business Partners. Troubleshoots endpoints, mobile devices, identity, connectivity, collaboration tools, AV, and workplace technology; coordinates complex issues across technical teams; prepares technology for leadership meetings, travel, and events; leads improvements, standards, documentation, mentoring, and executive support strategy. Requires after-hours coverage and occasional onsite, travel, event, or residential support.

Provide Tier 1 and Tier 2 IT support, executive assistance, onboarding, SaaS administration, and IT systems management. Configure MDM, SSO, ticketing, and identity systems; automate provisioning and offboarding; support IT security initiatives; manage SaaS spend; and coordinate technology requirements for new office buildouts, including networking, audiovisual, and security equipment.

Leads end-user technology services, supporting workstations, mobile devices, video conferencing, voice systems, and collaboration tools. Troubleshoots complex technical issues, manages incidents and root-cause analysis, automates operational tasks with scripting, creates documentation and training, coordinates vendors and technology projects, and supports hardware lifecycle activities. Provides rotational 24x7 on-call coverage and domestic and international deployment support.

Leads on-site IT service operations for a higher education campus, supervising service desk, classroom technology, and event support staff. Oversees service levels, incident escalation, classroom and examination technology readiness, A/V system lifecycle management, budgets, vendors, installations, and operational planning. Communicates outages and service changes to campus stakeholders and ensures reliable technology support across academic activities and events.

Own employee IT support, device lifecycle management, identity and SaaS administration, office infrastructure, onboarding, and scalable IT processes. The role supports macOS and Windows environments, MDM, SSO, Google Workspace, Slack, networking, AV, conference rooms, access controls, compliance, and asset management. It is a hands-on, on-site position requiring strong troubleshooting, documentation, communication, and customer-service skills.

Own day-to-day IT operations for the San Francisco office and hybrid workforce. Responsibilities include helpdesk support, onboarding and offboarding, Okta administration, MDM fleet management, Google Workspace and SaaS administration, AV and conference room support, office networking, asset management, documentation, and SOC 2/ISO 27001 compliance support. The role also administers enterprise AI tools and supports automation, security, and internal audits.

Leads enterprise IT strategy, operations, cybersecurity, compliance, infrastructure, business applications, and end-user services. Manages internal IT leaders, MSPs, and strategic technology partners while improving service delivery, employee technology experience, business continuity, and disaster recovery. Partners cross-functionally to support clinical and corporate platforms, strengthen security, and enable responsible AI and automation. Owns IT investment planning, vendor performance, operational metrics, and technology roadmaps in a regulated biopharmaceutical environment.

Owns day-to-day IT operations across headquarters and more than twenty software businesses. The role will standardize identity, endpoint, SaaS, device lifecycle, security, onboarding, incident response, vulnerability management, documentation, and acquisition integrations. It will also optimize cloud costs, evaluate vendors and managed services, establish governance, and recommend the long-term IT operating model. This is a hands-on builder role requiring practical judgment, strong communication, and the ability to create reliable, repeatable processes in an ambiguous environment.

Own and automate employee joiner, mover, and leaver processes across HR, identity, collaboration, ticketing, and SaaS platforms. Administer Okta, Jira Service Management, Google Workspace, Atlassian, Slack, and Zoom; build Python, API, orchestration, and AI-assisted workflows with strong security controls. Manage SaaS and non-human identities, licenses, audit evidence, and automation governance while partnering cross-functionally to improve service delivery and reduce manual effort.

Manage IT operations, support-team performance, technical escalations, identity and access management, macOS endpoint administration, collaboration and telephony systems, service workflows, automation, reporting, license utilization, and audit readiness. The role partners with Security and cross-functional teams to maintain compliant systems, improve onboarding and offboarding, establish operational standards, and enhance IT efficiency through automation and AI.

Administer EDI activities involving Medicare claims, COBRA crossover, Section 111, and data-sharing agreements. Monitor file processing, troubleshoot transmission and transaction errors, manage workflow queues, maintain documentation and business rules, conduct audits, and support stakeholders through an EDI hotline. Coordinate with technical teams, CMS, insurers, employers, vendors, and business partners; assist with testing, customer training, system transitions, and process improvements. This is a fully remote role.

Provides Level 1–3 technical support to attorneys and staff, diagnosing hardware, software, operating system, connectivity, and user-support issues. Supports system administration, cloud services, security protocols, infrastructure maintenance, employee technology setup and training, and firm-wide IT projects such as upgrades and software deployments.

Manages Pulmovant’s enterprise application portfolio, including validated GxP and clinical systems and core IT platforms. Oversees system performance, configuration, compliance, access, documentation, integrations, upgrades, and validation. Partners with Clinical, Regulatory, Quality, Finance, and HR stakeholders, manages vendors and an applications team, and leads continuous improvement, root-cause analysis, and application initiatives. The role also supports AI and machine learning governance, model validation, and responsible data practices.

Own end-to-end IT support and administration across identity, collaboration, AI, endpoint, and email platforms. Build AI-assisted triage, self-service, and agentic workflows; manage Claude Enterprise and MCP connectors; administer Jamf and Intune fleets; support onboarding and offboarding automation; oversee access reviews, MFA, phishing reports, and basic incident triage. The role requires strong judgment about automation versus human support, cross-functional ownership, and clear, personal communication.

Lead and manage all property IT operations including PMS, POS, network, servers, Active Directory, backups and security. Provide 24/7 system availability, end-user and guest support, vendor/contracts management, budgeting, and implementation of corporate technology standards and projects.

Own IT operations for a 60-person hybrid company, including end-user support, Mac fleet and device management, identity and access administration, SaaS and vendor management, office networking and AV, onboarding and offboarding, security configurations, and process documentation. Administer AI tools, support adoption and training, evaluate technology, manage licenses and costs, and establish scalable IT workflows as the company grows.

Provide second-level technical support to employees and executives, troubleshoot and maintain hardware, software, networks, conferencing, and audiovisual systems, and manage IT assets. Lead training, documentation, knowledge-base development, process improvements, security policy implementation, vendor coordination, system monitoring, and project initiatives. The role requires five days per week in the office, hands-on technical work, lifting up to 50 pounds, and travel to OpenGov facilities as needed.

Lead and execute remote technical implementations for dental practices from signing through go-live. Configure PMS integrations, set up remote access and network configurations, manage AWS-hosted Windows VMs/ETL, handle support volume, liaise with MSPs, and improve onboarding processes and automation while partnering with cross-functional teams.

Supports laboratory computing environments, scientific instruments, laboratory software, connected workstations, and IT infrastructure in a regulated biotech or pharmaceutical setting. Responsibilities include deployments, upgrades, troubleshooting, network connectivity, security patching, compliance, CMDB and inventory maintenance, vendor coordination, laboratory expansions, technical documentation, and IT project leadership.

Leads and develops the internal IT helpdesk and systems administration team, shifting operations from reactive support to proactive service delivery. Owns IT roadmaps, cross-functional projects, vendor relationships, authentication and access standards, disaster recovery, security improvements, and process automation. Establishes measurable KPIs and audit-ready onboarding and offboarding workflows while improving documentation, service levels, workload visibility, and operational accountability.

Build and run a white-glove executive support function: own intake, SLAs, runbooks, and escalations for executives, ABPs, and board. Provide AV support for board meetings and exec rooms, handle urgent tech incidents, work shared ticket queue, participate in on-call rotation, maintain San Francisco on-site presence, and document processes and KB content.

Leads Docker’s global Information Technology organization, overseeing help desk services, application management, device lifecycle logistics, internal productivity tools, service metrics, SLAs, and continual improvement. Develops multi-year IT strategy and technology roadmaps, architects and optimizes the SaaS and cloud application ecosystem, manages technical debt, and partners with executives and technical leaders to support business growth. Builds a metrics-driven, customer-focused team and advances AI- and automation-first practices.

Provides senior technical leadership for IT support and operations in a remote healthcare technology environment. Owns complex escalations, incident resolution, root cause analysis, endpoint and identity administration, onboarding and offboarding, vendor escalations, documentation, automation, and reliability improvements. Coaches support staff, develops scalable processes, partners with Security, Compliance, Engineering, Product, and clinical teams, and communicates clearly during high-impact incidents affecting clinical workflows.